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The map label for this gene is ahpC [C]

Identifier: 15888804

GI number: 15888804

Start: 1472110

End: 1472766

Strand: Reverse

Name: ahpC [C]

Synonym: Atu1480

Alternate gene names: 15888804

Gene position: 1472766-1472110 (Counterclockwise)

Preceding gene: 159184773

Following gene: 159184772

Centisome position: 51.83

GC content: 59.67

Gene sequence:

>657_bases
ATGAGCCTGCGTATCAACGATATCGCCCCCGACTTCACCGCCGAGACCACCCAGGGTCCGGTGCGTTTTCACGACTGGAT
CGGCGATGGCTGGGCAGTCCTGTTTTCCCATCCGAAAAACTTCACGCCCGTGTGCACGACGGAACTCGGCGCCATGGGCG
GCCTGCAGCCGGAATTCGAAAAACGCGGCGTCAAGATCATCGGCATTTCGGTCGATCCGGTCGAAAGCCATGAAAAATGG
AAAGCCGATATTCGCACCGCGACCGGCTTCAATGTCGATTATCCGCTGATCGGCGACAAGGACCTGAAGGTGGCGAAGCT
CTATGACATGCTGCCGGCGGGTGCCGGCGACAGCTCCGAAGGCCGCACGCCTGCCGATAACGCCACCGTGCGCTCCGTCT
TCGTCATCGGCCCCGACAAGAAGATCAAACTGGTCCTCACCTACCCGATGACCACCGGCCGCAATTTCGATGAAATTCTC
CGCGCCATCGATTCCATCCAGCTCACCTCCAAACACCAGGTGGCGACGCCCGCCAACTGGAAGCAGGGAGAGGATGTCAT
CATCACCGCCGCCGTCTCCAATGAAGATGCGATTGCCCGTTTCGGCTCCTACGACACGGTTCTTCCGTATCTGCGCAAGA
CGAAGCAGCCCGGCTAA

Upstream 100 bases:

>100_bases
CTCTGGCCATTTCAGGCAAAAACCTTAAGCTCCTGCGCCGGACACAAATTGCAGAGAACCACCAGATTTTCAGTTCAAAT
CATCAGGGAGAAAGCACACT

Downstream 100 bases:

>100_bases
GCTGCTAACGAAAAACGGGGGCGGTGAACTATCATCGCCCCAGTCATCGCACTTCTCATGGCTTTATGATCCCGCCATGA
TAGTCAAGCCGGTACGTCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSLRINDIAPDFTAETTQGPVRFHDWIGDGWAVLFSHPKNFTPVCTTELGAMGGLQPEFEKRGVKIIGISVDPVESHEKW
KADIRTATGFNVDYPLIGDKDLKVAKLYDMLPAGAGDSSEGRTPADNATVRSVFVIGPDKKIKLVLTYPMTTGRNFDEIL
RAIDSIQLTSKHQVATPANWKQGEDVIITAAVSNEDAIARFGSYDTVLPYLRKTKQPG

Sequences:

>Translated_218_residues
MSLRINDIAPDFTAETTQGPVRFHDWIGDGWAVLFSHPKNFTPVCTTELGAMGGLQPEFEKRGVKIIGISVDPVESHEKW
KADIRTATGFNVDYPLIGDKDLKVAKLYDMLPAGAGDSSEGRTPADNATVRSVFVIGPDKKIKLVLTYPMTTGRNFDEIL
RAIDSIQLTSKHQVATPANWKQGEDVIITAAVSNEDAIARFGSYDTVLPYLRKTKQPG
>Mature_217_residues
SLRINDIAPDFTAETTQGPVRFHDWIGDGWAVLFSHPKNFTPVCTTELGAMGGLQPEFEKRGVKIIGISVDPVESHEKWK
ADIRTATGFNVDYPLIGDKDLKVAKLYDMLPAGAGDSSEGRTPADNATVRSVFVIGPDKKIKLVLTYPMTTGRNFDEILR
AIDSIQLTSKHQVATPANWKQGEDVIITAAVSNEDAIARFGSYDTVLPYLRKTKQPG

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=228, Percent_Identity=46.9298245614035, Blast_Score=204, Evalue=6e-53,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=30.1587301587302, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4505591, Length=189, Percent_Identity=30.6878306878307, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32455266, Length=189, Percent_Identity=30.6878306878307, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32455264, Length=189, Percent_Identity=30.6878306878307, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5453549, Length=159, Percent_Identity=29.559748427673, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483377, Length=151, Percent_Identity=29.1390728476821, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5802974, Length=151, Percent_Identity=29.1390728476821, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786822, Length=155, Percent_Identity=30.9677419354839, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=209, Percent_Identity=40.1913875598086, Blast_Score=160, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17554494, Length=158, Percent_Identity=30.379746835443, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204376, Length=168, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32565831, Length=168, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319407, Length=215, Percent_Identity=55.3488372093023, Blast_Score=234, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6323613, Length=158, Percent_Identity=28.4810126582279, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=158, Percent_Identity=28.4810126582279, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581278, Length=223, Percent_Identity=48.4304932735426, Blast_Score=200, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17975518, Length=205, Percent_Identity=45.8536585365854, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24652434, Length=203, Percent_Identity=45.8128078817734, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24652436, Length=203, Percent_Identity=45.320197044335, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21357347, Length=199, Percent_Identity=29.1457286432161, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17157991, Length=169, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641739, Length=169, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17738015, Length=184, Percent_Identity=30.9782608695652, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24656348, Length=159, Percent_Identity=29.559748427673, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17864676, Length=159, Percent_Identity=29.559748427673, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23919; Mature: 23788

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRINDIAPDFTAETTQGPVRFHDWIGDGWAVLFSHPKNFTPVCTTELGAMGGLQPEFE
CCEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEECHHHHCCCCCCCHHH
KRGVKIIGISVDPVESHEKWKADIRTATGFNVDYPLIGDKDLKVAKLYDMLPAGAGDSSE
HCCEEEEEEECCCCCCCHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
GRTPADNATVRSVFVIGPDKKIKLVLTYPMTTGRNFDEILRAIDSIQLTSKHQVATPANW
CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEECCCCCCCCCCCCC
KQGEDVIITAAVSNEDAIARFGSYDTVLPYLRKTKQPG
CCCCCEEEEEEECCCCHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLRINDIAPDFTAETTQGPVRFHDWIGDGWAVLFSHPKNFTPVCTTELGAMGGLQPEFE
CEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEECHHHHCCCCCCCHHH
KRGVKIIGISVDPVESHEKWKADIRTATGFNVDYPLIGDKDLKVAKLYDMLPAGAGDSSE
HCCEEEEEEECCCCCCCHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCC
GRTPADNATVRSVFVIGPDKKIKLVLTYPMTTGRNFDEILRAIDSIQLTSKHQVATPANW
CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEECCCCCCCCCCCCC
KQGEDVIITAAVSNEDAIARFGSYDTVLPYLRKTKQPG
CCCCCEEEEEEECCCCHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]