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The map label for this gene is dhaR [H]

Identifier: 15888336

GI number: 15888336

Start: 988649

End: 989275

Strand: Direct

Name: dhaR [H]

Synonym: Atu0993

Alternate gene names: 15888336

Gene position: 988649-989275 (Clockwise)

Preceding gene: 15888334

Following gene: 15888337

Centisome position: 34.79

GC content: 54.86

Gene sequence:

>627_bases
ATGAATGGTCAATCTGCGACGCGCACGCGTCTCATTTCGGAGGGAATGCGCCAGCTGCTCGCTCACGGGTATGAGGGCGT
GGGGATCGGCCCGATCCTGAAGGAAGTGGATGTCCCAAAAGGGTCGTTCTATTACTTCTTTGCGAGCAAGGACGACTTCG
TGGTGGCGGTCATCGAGGCCTACGAGCAAAAGTATGCGCATATCAGGGAGCGACTTTTTTCGGATACATCGTTGCGCGCG
TTGCAGCGCCTATCGGTATATTTTGAAACGCTGGAACTGGAGCTTAAGCAAGACGGGCCTTATGCAGGCTGCCTTTACGG
CGTCATTGCGCAGACTTCCGCAGGCCGTAGCGCTCTGGTTCGGGACGCGCTTGCTATTTCATTCGGGCGATGGGAGACGA
GTATTCGCGAACTGCTCACCCAAGCCCAATATGAAGACGATATTGCCGGCGATGAGGATGTATCGGATCTTTGCGCTTGT
ATCATCGAGGCTTACGAGGGTGCGCTTATTCGCGTGAAAGCCACGGGCGATATAGCCGCTTTCACCCGGTTTCGAATCAA
AGGCTTACAAAGGCTGATGGCGAACATGCATCACAATGGCCGCGTGGTTTCTGAAGACGGCCGTTAG

Upstream 100 bases:

>100_bases
AAGATATATGCCACTAGAACGTTCATGTGCTAGACTCATATAGGCATCGCTCCAAGGAGAGAAGTATGTATAATCAGCAA
TGTAGACGATCGGTCTAGTT

Downstream 100 bases:

>100_bases
GCTGACATTATTCAAGATGGTGCATAACTCCAGGATCGAAAACATGCTTTTGCGTTCTCTCGTTTCGAGACGTTAAACCA
ATCATACTTGACGGCCGAAA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNGQSATRTRLISEGMRQLLAHGYEGVGIGPILKEVDVPKGSFYYFFASKDDFVVAVIEAYEQKYAHIRERLFSDTSLRA
LQRLSVYFETLELELKQDGPYAGCLYGVIAQTSAGRSALVRDALAISFGRWETSIRELLTQAQYEDDIAGDEDVSDLCAC
IIEAYEGALIRVKATGDIAAFTRFRIKGLQRLMANMHHNGRVVSEDGR

Sequences:

>Translated_208_residues
MNGQSATRTRLISEGMRQLLAHGYEGVGIGPILKEVDVPKGSFYYFFASKDDFVVAVIEAYEQKYAHIRERLFSDTSLRA
LQRLSVYFETLELELKQDGPYAGCLYGVIAQTSAGRSALVRDALAISFGRWETSIRELLTQAQYEDDIAGDEDVSDLCAC
IIEAYEGALIRVKATGDIAAFTRFRIKGLQRLMANMHHNGRVVSEDGR
>Mature_208_residues
MNGQSATRTRLISEGMRQLLAHGYEGVGIGPILKEVDVPKGSFYYFFASKDDFVVAVIEAYEQKYAHIRERLFSDTSLRA
LQRLSVYFETLELELKQDGPYAGCLYGVIAQTSAGRSALVRDALAISFGRWETSIRELLTQAQYEDDIAGDEDVSDLCAC
IIEAYEGALIRVKATGDIAAFTRFRIKGLQRLMANMHHNGRVVSEDGR

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=99, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23214; Mature: 23214

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGQSATRTRLISEGMRQLLAHGYEGVGIGPILKEVDVPKGSFYYFFASKDDFVVAVIEA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHH
YEQKYAHIRERLFSDTSLRALQRLSVYFETLELELKQDGPYAGCLYGVIAQTSAGRSALV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCHHHHH
RDALAISFGRWETSIRELLTQAQYEDDIAGDEDVSDLCACIIEAYEGALIRVKATGDIAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHH
FTRFRIKGLQRLMANMHHNGRVVSEDGR
HHHHHHHHHHHHHHHHCCCCEEECCCCC
>Mature Secondary Structure
MNGQSATRTRLISEGMRQLLAHGYEGVGIGPILKEVDVPKGSFYYFFASKDDFVVAVIEA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHH
YEQKYAHIRERLFSDTSLRALQRLSVYFETLELELKQDGPYAGCLYGVIAQTSAGRSALV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCHHHHH
RDALAISFGRWETSIRELLTQAQYEDDIAGDEDVSDLCACIIEAYEGALIRVKATGDIAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHH
FTRFRIKGLQRLMANMHHNGRVVSEDGR
HHHHHHHHHHHHHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]