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The map label for this gene is infC [H]

Identifier: 15887604

GI number: 15887604

Start: 252141

End: 252563

Strand: Direct

Name: infC [H]

Synonym: Atu0254

Alternate gene names: 15887604

Gene position: 252141-252563 (Clockwise)

Preceding gene: 15887601

Following gene: 15887605

Centisome position: 8.87

GC content: 53.43

Gene sequence:

>423_bases
ATGCCGACGGATCAGGCTTTGAAAATGGCGGAAGAGGCCGGTCTCGATCTCGTCGAGATTTCGCCTAACGCTGAACCGCC
GGTATGCAAGATCCTCGATCTCGGCAAGCTTAAGTACTCGACCCAGAAAAAGGCCGCTGAAGCGCGCAAGAAACAGAAGA
TCGTCGAAGTCAAAGAAATCAAGATGCGCCCAAACATCGACACGCATGACTATGACGTGAAGATGAAGGCGATGAACCGG
TTCTTTGACGAGGGTGACAAGGTGAAGGTGACCCTGAAGTTCCGTGGCCGTGAAATGGCCCACCAGGAACTCGGCATGAA
GCTTCTCCTTCAGGTTAAGGAAGATACCCAGGCAATTGCCAAGGTGGAAGCCGAGCCGAAGCTGGAAGGCCGTCAGATGA
TGATGGTTCTCGCCCCGAGATAA

Upstream 100 bases:

>100_bases
CAAAGCCGATGCCCCCGTTAAGGAGGGCCCGCGCTCCAACCGGGAAATTCGGGTTCCCAGAGTTCAGCTTATTGATGAAG
AGGGCCAGAACCTCGGTAGC

Downstream 100 bases:

>100_bases
TTTGCGCCAGTTCTGAAAGCTGCGTAAATCACCGCCGCAAGGGGAAATTTTCATTCCCCGTTGCGCTTTTAGCCGACTGC
GGTTATAAGCGCGCGTCCGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MPTDQALKMAEEAGLDLVEISPNAEPPVCKILDLGKLKYSTQKKAAEARKKQKIVEVKEIKMRPNIDTHDYDVKMKAMNR
FFDEGDKVKVTLKFRGREMAHQELGMKLLLQVKEDTQAIAKVEAEPKLEGRQMMMVLAPR

Sequences:

>Translated_140_residues
MPTDQALKMAEEAGLDLVEISPNAEPPVCKILDLGKLKYSTQKKAAEARKKQKIVEVKEIKMRPNIDTHDYDVKMKAMNR
FFDEGDKVKVTLKFRGREMAHQELGMKLLLQVKEDTQAIAKVEAEPKLEGRQMMMVLAPR
>Mature_139_residues
PTDQALKMAEEAGLDLVEISPNAEPPVCKILDLGKLKYSTQKKAAEARKKQKIVEVKEIKMRPNIDTHDYDVKMKAMNRF
FDEGDKVKVTLKFRGREMAHQELGMKLLLQVKEDTQAIAKVEAEPKLEGRQMMMVLAPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=137, Percent_Identity=61.3138686131387, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 15982; Mature: 15851

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDQALKMAEEAGLDLVEISPNAEPPVCKILDLGKLKYSTQKKAAEARKKQKIVEVKEI
CCCHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHE
KMRPNIDTHDYDVKMKAMNRFFDEGDKVKVTLKFRGREMAHQELGMKLLLQVKEDTQAIA
EECCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHCHHHEEHHHHHHHHHH
KVEAEPKLEGRQMMMVLAPR
HCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
PTDQALKMAEEAGLDLVEISPNAEPPVCKILDLGKLKYSTQKKAAEARKKQKIVEVKEI
CCHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHE
KMRPNIDTHDYDVKMKAMNRFFDEGDKVKVTLKFRGREMAHQELGMKLLLQVKEDTQAIA
EECCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHCHHHEEHHHHHHHHHH
KVEAEPKLEGRQMMMVLAPR
HCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]