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The map label for this gene is chvG

Identifier: 15887391

GI number: 15887391

Start: 34679

End: 36469

Strand: Reverse

Name: chvG

Synonym: Atu0033

Alternate gene names: 15887391

Gene position: 36469-34679 (Counterclockwise)

Preceding gene: 159184131

Following gene: 15887390

Centisome position: 1.28

GC content: 60.64

Gene sequence:

>1791_bases
GTGTTGAAGAAAACGCCGGAAACCGTCTCGGACAGTGACGATGCCGAAGAACGCGGCAGCGAACGCCGCCATCGTATCCA
TCCGCTGACGATCATCCGGCGCATTTTCGGCAATGCGGTGTTTTCCAGCCTCACGCGCCGTATCCTCTTCTTCAATGTCG
CCGCGACCGTGGTTCTGGTCGGCGGCATTCTCTACCTCAACCAGTTCCGTGAAGGGCTGATCGACGCGCGCGTGGAAAGC
CTGTTGACGCAGGGCGAAATCATCGCCGGCGCGGTCTCCGCTTCCGCATCGGTCGATACCAACTCGATCACCATCAATCC
GGAAAAACTGCTCGAATTGCAGGCGGGGCAGAGCATCACCCCTGCCCCCAACGACGAGGATCTGAGTTTCCCGATCAACC
CGGAGCGAGTGGCGCCTGTGCTGCGGCGTCTGATTTCGCCGACACGCACGCGCGCGCGGCTGTTCGATGCCGATGCCAAT
CTGTTGCTCGATTCCCGCCACCTTTATTCACGCGGACAGGTTCTGCGCTTCGATCTGCCGCCGGTGACGCCGGAAACCCA
GACTTGGGGTGACTGGTTCACCAGCATGTTCAACCGCATGCTGCAGCCGAGCAGCCTGCCGCAATACAAGGAAGCGCCGG
GTGGCGATGGCTCGATCTATCCAGAAGTGATGAATGCGCTGACGGGGGTTCGCGGCGCGGTCGTGCGCGTGACCGAAAAG
GGTGAGCTGATCGTTTCGGTCGCCGTGCCGGTTCAGCGCTTCCGGGCCGTACTAGGCGTATTGCTTTTGTCCACCCAGGC
GGGAGATATCGACAAGATCGTGCATGCCGAGCGCCTTGCCATCATGCGCGTCTTCGGCATCGCCACGCTGGTCAATATCG
TGTTGTCACTGCTTTTATCCTCCACCATCGCCACGCCGCTAAGACGCCTTTCGGCGGCCGCGATCCGCGTGCGCCGCGGG
GCGAGAACGCGTGAGGAAATACCGGATTTCTCAGCGCGTCAGGACGAGATCGGAAACCTCTCCATAGCGTTGCGTGAAAT
GACGACGGCGCTCTACGACCGTATCGACGCCATCGAAAGTTTCGCCGCCGACGTCAGCCATGAACTCAAGAACCCGCTGA
CCTCGCTGCGCAGCGCCGTGGAAACCCTGCCACGCGCCAAGACCGAAGAGTCCAAACAGCGGCTGACCGAAATCATCTTC
CATGACGTTCGGCGCCTCGATCGCCTGATCAGCGATATTTCGGACGCGTCGCGCCTCGATGCCGAGCTGGCGCGCGCCGA
TGCTTCGCCACTCGACCTCGATGTGCTGATGAAGGGTCTGGTGGACATATCCCGCCAGATCAGCACCAAGAAAAAGAGCG
TGGCGATCGATTATGTCGCCGACCGGAAGGCCGGAGCCAAAACCTCTTTCGTAGTCAACGGCCACGATCTTCGTATCGGG
CAGATTGTCACCAACCTTATCGAGAATGCACGTTCTTTCGTTTCGGAGGAAAGCGGCCGCATCACCGTGCGCCTTTCCCG
CCACAAGGACCGCTGCATCGTGCAGGTGGAAGACAACGGCCCCGGCATTCAGGCAGAAGATATCGACCGAATTTTCGAGC
GGTTTTATACAGACCGGCCGGCCAGCGAAGGTTTCGGCCAGAATTCCGGCCTTGGCCTTTCCATCAGCCGCCAGATCGCG
GAAGCCCATGGCGGCAGCCTCCGGGCGGAAAACGTGGTCGACAAATACGGCGTTATATCAGGCGCGCGCTTCACCCTGTC
GCTGCCGGCGGCCGAAACCCATGAACGCTGA

Upstream 100 bases:

>100_bases
GAAACGCTTTATGGCGTAGGATATCGCTTCCGCGAAGCGGCTTAAAGAAGCCGACTCAAGCAGAAGGGACCGCCCGAACC
GGGCGTGAGGACTTTAATAC

Downstream 100 bases:

>100_bases
ACGCTTCAACCTGCATGCGACCGCCATCGTCGTCGACGGCACCGGCATCCTCTTCACGGGTCCGTCGGGAAGCGGCAAGA
GCGAGCTCGCCTTCAGCTTT

Product: two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MLKKTPETVSDSDDAEERGSERRHRIHPLTIIRRIFGNAVFSSLTRRILFFNVAATVVLVGGILYLNQFREGLIDARVES
LLTQGEIIAGAVSASASVDTNSITINPEKLLELQAGQSITPAPNDEDLSFPINPERVAPVLRRLISPTRTRARLFDADAN
LLLDSRHLYSRGQVLRFDLPPVTPETQTWGDWFTSMFNRMLQPSSLPQYKEAPGGDGSIYPEVMNALTGVRGAVVRVTEK
GELIVSVAVPVQRFRAVLGVLLLSTQAGDIDKIVHAERLAIMRVFGIATLVNIVLSLLLSSTIATPLRRLSAAAIRVRRG
ARTREEIPDFSARQDEIGNLSIALREMTTALYDRIDAIESFAADVSHELKNPLTSLRSAVETLPRAKTEESKQRLTEIIF
HDVRRLDRLISDISDASRLDAELARADASPLDLDVLMKGLVDISRQISTKKKSVAIDYVADRKAGAKTSFVVNGHDLRIG
QIVTNLIENARSFVSEESGRITVRLSRHKDRCIVQVEDNGPGIQAEDIDRIFERFYTDRPASEGFGQNSGLGLSISRQIA
EAHGGSLRAENVVDKYGVISGARFTLSLPAAETHER

Sequences:

>Translated_596_residues
MLKKTPETVSDSDDAEERGSERRHRIHPLTIIRRIFGNAVFSSLTRRILFFNVAATVVLVGGILYLNQFREGLIDARVES
LLTQGEIIAGAVSASASVDTNSITINPEKLLELQAGQSITPAPNDEDLSFPINPERVAPVLRRLISPTRTRARLFDADAN
LLLDSRHLYSRGQVLRFDLPPVTPETQTWGDWFTSMFNRMLQPSSLPQYKEAPGGDGSIYPEVMNALTGVRGAVVRVTEK
GELIVSVAVPVQRFRAVLGVLLLSTQAGDIDKIVHAERLAIMRVFGIATLVNIVLSLLLSSTIATPLRRLSAAAIRVRRG
ARTREEIPDFSARQDEIGNLSIALREMTTALYDRIDAIESFAADVSHELKNPLTSLRSAVETLPRAKTEESKQRLTEIIF
HDVRRLDRLISDISDASRLDAELARADASPLDLDVLMKGLVDISRQISTKKKSVAIDYVADRKAGAKTSFVVNGHDLRIG
QIVTNLIENARSFVSEESGRITVRLSRHKDRCIVQVEDNGPGIQAEDIDRIFERFYTDRPASEGFGQNSGLGLSISRQIA
EAHGGSLRAENVVDKYGVISGARFTLSLPAAETHER
>Mature_596_residues
MLKKTPETVSDSDDAEERGSERRHRIHPLTIIRRIFGNAVFSSLTRRILFFNVAATVVLVGGILYLNQFREGLIDARVES
LLTQGEIIAGAVSASASVDTNSITINPEKLLELQAGQSITPAPNDEDLSFPINPERVAPVLRRLISPTRTRARLFDADAN
LLLDSRHLYSRGQVLRFDLPPVTPETQTWGDWFTSMFNRMLQPSSLPQYKEAPGGDGSIYPEVMNALTGVRGAVVRVTEK
GELIVSVAVPVQRFRAVLGVLLLSTQAGDIDKIVHAERLAIMRVFGIATLVNIVLSLLLSSTIATPLRRLSAAAIRVRRG
ARTREEIPDFSARQDEIGNLSIALREMTTALYDRIDAIESFAADVSHELKNPLTSLRSAVETLPRAKTEESKQRLTEIIF
HDVRRLDRLISDISDASRLDAELARADASPLDLDVLMKGLVDISRQISTKKKSVAIDYVADRKAGAKTSFVVNGHDLRIG
QIVTNLIENARSFVSEESGRITVRLSRHKDRCIVQVEDNGPGIQAEDIDRIFERFYTDRPASEGFGQNSGLGLSISRQIA
EAHGGSLRAENVVDKYGVISGARFTLSLPAAETHER

Specific function: Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=27.9835390946502, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=256, Percent_Identity=27.734375, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790346, Length=284, Percent_Identity=26.056338028169, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=378, Percent_Identity=24.8677248677249, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=290, Percent_Identity=24.4827586206897, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787894, Length=319, Percent_Identity=27.8996865203762, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=26.0504201680672, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=26.890756302521, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=23.8866396761134, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=262, Percent_Identity=23.6641221374046, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=270, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788279, Length=320, Percent_Identity=23.75, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=314, Percent_Identity=28.0254777070064, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789403, Length=294, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=274, Percent_Identity=27.7372262773723, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=27.5, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790551, Length=258, Percent_Identity=26.3565891472868, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790300, Length=218, Percent_Identity=27.9816513761468, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHVG_AGRT5 (Q07737)

Other databases:

- EMBL:   L18860
- EMBL:   AE007869
- PIR:   A49902
- PIR:   AB2581
- PIR:   H97362
- RefSeq:   NP_353072.1
- ProteinModelPortal:   Q07737
- STRING:   Q07737
- GeneID:   1132071
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0033
- eggNOG:   COG0642
- HOGENOM:   HBG294236
- OMA:   ILYLNQF
- ProtClustDB:   CLSK864189
- BioCyc:   ATUM176299-1:ATU0033-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00304
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 65723; Mature: 65723

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0xb3c0ff0)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKTPETVSDSDDAEERGSERRHRIHPLTIIRRIFGNAVFSSLTRRILFFNVAATVVLV
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGILYLNQFREGLIDARVESLLTQGEIIAGAVSASASVDTNSITINPEKLLELQAGQSIT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHCCCCCC
PAPNDEDLSFPINPERVAPVLRRLISPTRTRARLFDADANLLLDSRHLYSRGQVLRFDLP
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCEECCHHHHCCCCEEEEECC
PVTPETQTWGDWFTSMFNRMLQPSSLPQYKEAPGGDGSIYPEVMNALTGVRGAVVRVTEK
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
GELIVSVAVPVQRFRAVLGVLLLSTQAGDIDKIVHAERLAIMRVFGIATLVNIVLSLLLS
CCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STIATPLRRLSAAAIRVRRGARTREEIPDFSARQDEIGNLSIALREMTTALYDRIDAIES
HHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHH
FAADVSHELKNPLTSLRSAVETLPRAKTEESKQRLTEIIFHDVRRLDRLISDISDASRLD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELARADASPLDLDVLMKGLVDISRQISTKKKSVAIDYVADRKAGAKTSFVVNGHDLRIG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCCCEEEECCCCCHHH
QIVTNLIENARSFVSEESGRITVRLSRHKDRCIVQVEDNGPGIQAEDIDRIFERFYTDRP
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCC
ASEGFGQNSGLGLSISRQIAEAHGGSLRAENVVDKYGVISGARFTLSLPAAETHER
CCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCHHCCCH
>Mature Secondary Structure
MLKKTPETVSDSDDAEERGSERRHRIHPLTIIRRIFGNAVFSSLTRRILFFNVAATVVLV
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGILYLNQFREGLIDARVESLLTQGEIIAGAVSASASVDTNSITINPEKLLELQAGQSIT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHCCCCCC
PAPNDEDLSFPINPERVAPVLRRLISPTRTRARLFDADANLLLDSRHLYSRGQVLRFDLP
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCEECCHHHHCCCCEEEEECC
PVTPETQTWGDWFTSMFNRMLQPSSLPQYKEAPGGDGSIYPEVMNALTGVRGAVVRVTEK
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
GELIVSVAVPVQRFRAVLGVLLLSTQAGDIDKIVHAERLAIMRVFGIATLVNIVLSLLLS
CCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STIATPLRRLSAAAIRVRRGARTREEIPDFSARQDEIGNLSIALREMTTALYDRIDAIES
HHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHH
FAADVSHELKNPLTSLRSAVETLPRAKTEESKQRLTEIIFHDVRRLDRLISDISDASRLD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELARADASPLDLDVLMKGLVDISRQISTKKKSVAIDYVADRKAGAKTSFVVNGHDLRIG
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCCCEEEECCCCCHHH
QIVTNLIENARSFVSEESGRITVRLSRHKDRCIVQVEDNGPGIQAEDIDRIFERFYTDRP
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCC
ASEGFGQNSGLGLSISRQIAEAHGGSLRAENVVDKYGVISGARFTLSLPAAETHER
CCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8407839; 11743193; 11743194