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The map label for this gene is glpT [H]

Identifier: 57652596

GI number: 57652596

Start: 413356

End: 414714

Strand: Reverse

Name: glpT [H]

Synonym: SACOL0407

Alternate gene names: 57652596

Gene position: 414714-413356 (Counterclockwise)

Preceding gene: 57652600

Following gene: 57652592

Centisome position: 14.76

GC content: 37.09

Gene sequence:

>1359_bases
ATGAATTTTCTTAAACCTGCAAAGCATATTAAGCCTTTGCCAGAAAATCAGATAGATGATACCTATAAACGATTACGTCT
CCAAGTATTTCTTGGTATTTTCATCGGTTACGCTGGGTACTATTTATTACGTAAAAACTTTTCGTTAGCGATGCCGGCAT
TGCAAGAGCAAGGTTTTACAAAAGCGGAACTAGGTTTTGCACTTTCTGCTGTTTCCATCGCATATGGATTTAGTAAGTTC
TTTATGGGTACTGTAAGTGATCGGAGCAATGCTCGGATATTCTTAGTTCTTGGATTAGCACTCACTGCTATCGTCAATTT
GTTAATGGGATTTGTACCGTTCTTTACATCAGGTATCGGTATTATGTTTGTCCTATTATTCTTAAATGGATGGTTTCAAG
GTATGGGCTGGCCACCTTCAGGCCGTGTTCTCGTTCACTGGTTTAGTGTAAGTGAACGCGGAAGTAAGACTGCCCTTTGG
AACGTTGCGCATAATGTTGGTGGAGGTATTATGGCACCTATTGCTGCTTGGGGTATTACAACAACTGCATTTATCAACTT
TGGTTATTTAAAAGGTTTCGAAGGTGTATTCATTTACCCTGCACTCTTAGCACTTATCATTGCCGCAATTTCATACGTAT
TGATTAGAGACACACCTCAATCTCAAGGTTTACCTCCAATCGAAATTTATAAAAATGACTTTGCTACAAGCGATAAGAAA
ACATTAGAAACAGAATTAACTACAAAAGAAATTTTATTTAAATATGTACTGAACAATAAATGGGTATGGGCAATTGCCTT
TGCAAATATATTTGTTTATTTCGTGCGTTATGGTGTACTTGATTGGGCGCCAGTCTACTTAAGTGAAGAAAAACATTTCG
ACTTAAAAGCATCAGGTTGGGCATACTTCTTATACGAATGGGCTGGAATTCCTGGTACATTATTATGTGGTTACATTTCT
GATAAATTATTCAAAGGTCGTCGTGGACCTGCAGGTTTCTTCTTTATGTTAGGTGTCACAGTATTTGTATTAATTTATTG
GTTAAATCCTCCAGGCAATGCTTGGTTAGACAATGTCTCATTAATTGCCATTGGTTTCTTAATATATGGACCAGTTATGT
TAATTGGTTTACAAGCATTAGATTATGTACCTAAAAAAGCAGCTGGCACAGCAGCTGGATTAACAGGATTATTTGGTTAT
CTGTTTGGTGCTGTAATGGCCAACATCGTCTTAGGTGCTGTAGTTGATAAATTCGGATGGGATGTCGGTTTTATTTTATT
AACAGCAATTAGTGTGTTTGCAATGTTGAGCTTTATCCTCACTTGGAATAAAGTAGGACAAGAAACCGTTCATCATTAA

Upstream 100 bases:

>100_bases
TATGCAAGATTTCACAAAAGCATATTGACAACGCTTTCATACATGTCTAATATAAGTTTATCGCACAAAATGCATATAAA
TACATATTAAGGAGGATTTT

Downstream 100 bases:

>100_bases
ATGATAAAAAATAAAGTCATATGGTTATCTTATCGAAAGATGATATATTCATCTCTTATAAGTTCAACCATATGACTTTT
TATTAGTATTCAAAAAAATA

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF
FMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW
NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS
DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY
LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH

Sequences:

>Translated_452_residues
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF
FMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW
NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS
DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY
LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH
>Mature_452_residues
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKF
FMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW
NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYIS
DKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGY
LFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETVHH

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=435, Percent_Identity=27.816091954023, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4503847, Length=435, Percent_Identity=27.816091954023, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI256219483, Length=435, Percent_Identity=27.816091954023, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI256219543, Length=456, Percent_Identity=26.7543859649123, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI256219564, Length=366, Percent_Identity=25.1366120218579, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI223717983, Length=472, Percent_Identity=23.3050847457627, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI38093649, Length=472, Percent_Identity=23.3050847457627, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI46361976, Length=470, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI49619231, Length=335, Percent_Identity=23.2835820895522, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788573, Length=452, Percent_Identity=56.858407079646, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI87082310, Length=442, Percent_Identity=37.10407239819, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI2367259, Length=395, Percent_Identity=33.6708860759494, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI2367379, Length=324, Percent_Identity=25.9259259259259, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789515, Length=445, Percent_Identity=23.3707865168539, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082320, Length=434, Percent_Identity=23.2718894009217, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789152, Length=439, Percent_Identity=23.0068337129841, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17542316, Length=466, Percent_Identity=24.2489270386266, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564202, Length=446, Percent_Identity=23.9910313901345, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI133901854, Length=474, Percent_Identity=23.4177215189873, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI133901856, Length=474, Percent_Identity=23.4177215189873, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564204, Length=378, Percent_Identity=24.6031746031746, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI133930953, Length=466, Percent_Identity=22.3175965665236, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656866, Length=481, Percent_Identity=22.8690228690229, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550478, Length=481, Percent_Identity=22.8690228690229, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24656861, Length=481, Percent_Identity=22.8690228690229, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50169; Mature: 50169

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFT
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHCCCC
KAELGFALSAVSIAYGFSKFFMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALWNVAHNVGGGIMAPIAAWGIT
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
TTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
HHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHEECCCCCCCCHH
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGW
HHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCHHEECCCCCCCEECCCE
AYFLYEWAGIPGTLLCGYISDKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVS
EEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCCHHCCHH
LIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGYLFGAVMANIVLGAVVDKFGW
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DVGFILLTAISVFAMLSFILTWNKVGQETVHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLRKNFSLAMPALQEQGFT
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHCCCC
KAELGFALSAVSIAYGFSKFFMGTVSDRSNARIFLVLGLALTAIVNLLMGFVPFFTSGIG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
IMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALWNVAHNVGGGIMAPIAAWGIT
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
TTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDTPQSQGLPPIEIYKNDFATSDKK
HHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHEECCCCCCCCHH
TLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVRYGVLDWAPVYLSEEKHFDLKASGW
HHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCHHEECCCCCCCEECCCE
AYFLYEWAGIPGTLLCGYISDKLFKGRRGPAGFFFMLGVTVFVLIYWLNPPGNAWLDNVS
EEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCCHHCCHH
LIAIGFLIYGPVMLIGLQALDYVPKKAAGTAAGLTGLFGYLFGAVMANIVLGAVVDKFGW
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DVGFILLTAISVFAMLSFILTWNKVGQETVHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]