Click here to switch to the map view.

The map label for this gene is fadN [H]

Identifier: 57652490

GI number: 57652490

Start: 249372

End: 251633

Strand: Reverse

Name: fadN [H]

Synonym: SACOL0212

Alternate gene names: 57652490

Gene position: 251633-249372 (Counterclockwise)

Preceding gene: 57652491

Following gene: 57652489

Centisome position: 8.96

GC content: 37.36

Gene sequence:

>2262_bases
ATGACAATTAATAAAGTAACCGTTCTTGGCGCAGGCACAATGGGCGCTCAACTGGCAGCACTTTTTGTGAATGCTGGACT
TAAAGTAAAACTATTAGATATTGTAGTGGACAAAAACGATCCAAATCTCATTGCGAAAAAATCTTACGATAAAATTACAG
ATAAGAAACGGCCGCTACTATTCGACTTAAATCTAGCGAGTCATTTAACATATGGTAATTTTGATGATGACTTGGTAAAT
GATGATGCTGATTTATATATCGAAGCAGTCAAAGAAGATATTGAAATTAAGCATGCTGTTTGGCAACAAGTTCTACAACA
TGCTAAAGAAGATGCTTTATTCGCTACAAATACATCAGGTATTCCAATTAATGCGATTGCTCAAGCATTTAACGAGAAGG
ATCAAGAACGATTCTTTGGTCTACATTTCTTTAACCCACCACGTATTATGAAATTAGTGGAGTTAATACCTACGTCACAC
ACGAAGGAATCTATTATATTAGATGTAAAAAATTTCGCGCAAAATGTGTTAGGTAAAGGTGTCATTGTCGTCAATGATGT
GCCTGGCTTTGTCGCAAATAGAGTCGGCACGCAAACAATGAATGATATTATGTATCGCGCCGAGCAACACAAGATAAGCA
TTGTAGATGTGGATGCTTTAACTGGGCAAGCGATTGGTCGTCCTAAAACAGGTACATATGCGCTATCTGACCTAGTCGGT
TTAGATATTGCAGTGTCTGTAATTAAAGGCATGCAACAAGTACCTGAAGAAACACCTTATTTTCATGATGTCAAAATTGT
AAATACGTTGTTTGACAATGGCGCACTCGGACGTAAAACGAAACAAGGATTTTACAAAAAGGATAAAGAAACTAAAGCTC
GACTTGTTTACGATGTTGAAAAACAAGATTATGTACCTGTATCGCAACCACAATTACCAATTTTAAATGAATTTAATAAA
GACTTAGTGCATAACCTTGATACCATATTCAATGCGCAAGACGAAGCGGGACTATTTTTATGGGAGACATTACGTAATAA
TTTCTATTACTCTGCTATCAATGTACCTAAAGCTACCGATGATTTCCGAGACATAGACCGTGCGCTTGTCTGGGGGTTCA
ACTGGAAACTTGGTCCATTCCAATTATGGGATGCAATGGGATACGAACGTGTTAAAACACGTATGGAAGACGAACTTGGA
GACTTACCACAATGGATTAGTGATTTAGATGGTGGCTTTTATAAACAAGATGAGACCATTGAATATGCAACACCTATTTC
TCACTTCGTAAAAGATGAACTTTGGGATAAAGGTGATGCCAAACTTTCCGTAACTCATGATGATCAACTGTTACTGAAAT
TACAAAGTAAAAATAATGTCATTACCGATGAATTCAACGATGCGTTAGTTGATGCGATTGATTTACTGGAAAATGACCAT
TACACAAGTATGGTTATTTATGCAGATGGTAACAATTTCAGTGTGGGTGCTAACCTTTTCTTAATGAAAAAGGCGCATGA
AGACGGTCTTGTAGATGATGTCGTTGCACAATCAATTGATAAATTACATTATAGCTTTAATCGTTTGAAGTATAGTTTGA
AACCAGTAGTCACAGCTGTTCAAGGTCGTGCCTTAGGCGGTGGCTGTGAGCTTGTACTTTACTCACCTATTGTTGTCGCT
GCAAGTGAAACATATATCGGTCTTGTTGAAGCAGGTGTTGGCTTATTACCGAGTGGCGGTGGCCTTGCAGAAATGGCTGA
TCGCATATTACGCACATCGCATAAGTTTGATGACAAACAAGCTTCCATGACAAAAGTACTGACGAATATCGCATTTGCGA
AAGTCTCTACAAATGCCTTTGAGGCACGTCGTTATGGTTATTTACGTGATACAGATACGATTATTTTCAATACAGCACAA
CGTGTCGAAGTTGCGCTCAAACGTGCGAAATATGAAGCAGAAACAAACTATATTCCGAATCCTAGACATCAATATATCGC
TTTAGGTGAAGACTTCAAAGCATTGATCCAAGGACAATTAGATGCGCAAAGACGGGGTCATTTTATTAGCGACCATGATT
ATCATATTGCCTTAAATATCGCCACAATTTTAGCGGGTGGTGATTTACCAAGAAATACATTTATCAATCAACGTTACATT
CAATCGTTGGAGAAAATTGGCTTTATTGACTTACTAAAATCTAAAAAATCATATGAAAGAATTGCACATATGTTAAAAAC
TGGTAAGCCATTACGTAATTAA

Upstream 100 bases:

>100_bases
AGATGACTGTCAAAGATACTTAATTAATTTTATAAAATAGCAACGTTATTCCAATTATCTTAATGGTTATCTTATCCTCA
ACTAAATTGGAGGAATCACT

Downstream 100 bases:

>100_bases
AAGATAGTCATTAAGAGAGGATGATAACCATGCAAGAAGCATACATTGTAGCTTATGGGCGTTCAGCCGCAGCGAAAGCA
AAGCAAGGCGCATTATTCCA

Product: 3-hydroxyacyl-CoA dehydrogenase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 752

Protein sequence:

>753_residues
MTINKVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAKKSYDKITDKKRPLLFDLNLASHLTYGNFDDDLVN
DDADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSGIPINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSH
TKESIILDVKNFAQNVLGKGVIVVNDVPGFVANRVGTQTMNDIMYRAEQHKISIVDVDALTGQAIGRPKTGTYALSDLVG
LDIAVSVIKGMQQVPEETPYFHDVKIVNTLFDNGALGRKTKQGFYKKDKETKARLVYDVEKQDYVPVSQPQLPILNEFNK
DLVHNLDTIFNAQDEAGLFLWETLRNNFYYSAINVPKATDDFRDIDRALVWGFNWKLGPFQLWDAMGYERVKTRMEDELG
DLPQWISDLDGGFYKQDETIEYATPISHFVKDELWDKGDAKLSVTHDDQLLLKLQSKNNVITDEFNDALVDAIDLLENDH
YTSMVIYADGNNFSVGANLFLMKKAHEDGLVDDVVAQSIDKLHYSFNRLKYSLKPVVTAVQGRALGGGCELVLYSPIVVA
ASETYIGLVEAGVGLLPSGGGLAEMADRILRTSHKFDDKQASMTKVLTNIAFAKVSTNAFEARRYGYLRDTDTIIFNTAQ
RVEVALKRAKYEAETNYIPNPRHQYIALGEDFKALIQGQLDAQRRGHFISDHDYHIALNIATILAGGDLPRNTFINQRYI
QSLEKIGFIDLLKSKKSYERIAHMLKTGKPLRN

Sequences:

>Translated_753_residues
MTINKVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAKKSYDKITDKKRPLLFDLNLASHLTYGNFDDDLVN
DDADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSGIPINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSH
TKESIILDVKNFAQNVLGKGVIVVNDVPGFVANRVGTQTMNDIMYRAEQHKISIVDVDALTGQAIGRPKTGTYALSDLVG
LDIAVSVIKGMQQVPEETPYFHDVKIVNTLFDNGALGRKTKQGFYKKDKETKARLVYDVEKQDYVPVSQPQLPILNEFNK
DLVHNLDTIFNAQDEAGLFLWETLRNNFYYSAINVPKATDDFRDIDRALVWGFNWKLGPFQLWDAMGYERVKTRMEDELG
DLPQWISDLDGGFYKQDETIEYATPISHFVKDELWDKGDAKLSVTHDDQLLLKLQSKNNVITDEFNDALVDAIDLLENDH
YTSMVIYADGNNFSVGANLFLMKKAHEDGLVDDVVAQSIDKLHYSFNRLKYSLKPVVTAVQGRALGGGCELVLYSPIVVA
ASETYIGLVEAGVGLLPSGGGLAEMADRILRTSHKFDDKQASMTKVLTNIAFAKVSTNAFEARRYGYLRDTDTIIFNTAQ
RVEVALKRAKYEAETNYIPNPRHQYIALGEDFKALIQGQLDAQRRGHFISDHDYHIALNIATILAGGDLPRNTFINQRYI
QSLEKIGFIDLLKSKKSYERIAHMLKTGKPLRN
>Mature_752_residues
TINKVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAKKSYDKITDKKRPLLFDLNLASHLTYGNFDDDLVND
DADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSGIPINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSHT
KESIILDVKNFAQNVLGKGVIVVNDVPGFVANRVGTQTMNDIMYRAEQHKISIVDVDALTGQAIGRPKTGTYALSDLVGL
DIAVSVIKGMQQVPEETPYFHDVKIVNTLFDNGALGRKTKQGFYKKDKETKARLVYDVEKQDYVPVSQPQLPILNEFNKD
LVHNLDTIFNAQDEAGLFLWETLRNNFYYSAINVPKATDDFRDIDRALVWGFNWKLGPFQLWDAMGYERVKTRMEDELGD
LPQWISDLDGGFYKQDETIEYATPISHFVKDELWDKGDAKLSVTHDDQLLLKLQSKNNVITDEFNDALVDAIDLLENDHY
TSMVIYADGNNFSVGANLFLMKKAHEDGLVDDVVAQSIDKLHYSFNRLKYSLKPVVTAVQGRALGGGCELVLYSPIVVAA
SETYIGLVEAGVGLLPSGGGLAEMADRILRTSHKFDDKQASMTKVLTNIAFAKVSTNAFEARRYGYLRDTDTIIFNTAQR
VEVALKRAKYEAETNYIPNPRHQYIALGEDFKALIQGQLDAQRRGHFISDHDYHIALNIATILAGGDLPRNTFINQRYIQ
SLEKIGFIDLLKSKKSYERIAHMLKTGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=297, Percent_Identity=31.986531986532, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI20127408, Length=407, Percent_Identity=29.2383292383292, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI296179427, Length=314, Percent_Identity=30.2547770700637, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI261878539, Length=302, Percent_Identity=28.8079470198675, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI68989263, Length=302, Percent_Identity=28.8079470198675, Blast_Score=94, Evalue=5e-19,
Organism=Escherichia coli, GI1787661, Length=323, Percent_Identity=27.8637770897833, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790281, Length=245, Percent_Identity=34.2857142857143, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788682, Length=395, Percent_Identity=26.3291139240506, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787659, Length=233, Percent_Identity=28.3261802575107, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17549919, Length=298, Percent_Identity=34.8993288590604, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17553560, Length=297, Percent_Identity=31.3131313131313, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17563036, Length=290, Percent_Identity=29.3103448275862, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17558304, Length=414, Percent_Identity=28.0193236714976, Blast_Score=113, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17508953, Length=288, Percent_Identity=30.5555555555556, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17508951, Length=413, Percent_Identity=27.6029055690073, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144276, Length=288, Percent_Identity=30.5555555555556, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985930, Length=405, Percent_Identity=25.4320987654321, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985923, Length=415, Percent_Identity=24.0963855421687, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19921000, Length=446, Percent_Identity=28.47533632287, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583077, Length=446, Percent_Identity=28.47533632287, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583079, Length=446, Percent_Identity=28.47533632287, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45549573, Length=226, Percent_Identity=22.5663716814159, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 84609; Mature: 84478

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINKVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAKKSYDKITDKKRPLL
CCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEECCCHHHHCCCCCCEE
FDLNLASHLTYGNFDDDLVNDDADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSG
EEECHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
IPINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSHTKESIILDVKNFAQNVLGKG
CCHHHHHHHHCCCCHHHEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCC
VIVVNDVPGFVANRVGTQTMNDIMYRAEQHKISIVDVDALTGQAIGRPKTGTYALSDLVG
EEEEECCCCHHHHHHCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
LDIAVSVIKGMQQVPEETPYFHDVKIVNTLFDNGALGRKTKQGFYKKDKETKARLVYDVE
HHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCHHHHCCHHCCCCCCEEEEEEEC
KQDYVPVSQPQLPILNEFNKDLVHNLDTIFNAQDEAGLFLWETLRNNFYYSAINVPKATD
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEEECCCCCCH
DFRDIDRALVWGFNWKLGPFQLWDAMGYERVKTRMEDELGDLPQWISDLDGGFYKQDETI
HHHHHHHHHEECCCCCCCHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCE
EYATPISHFVKDELWDKGDAKLSVTHDDQLLLKLQSKNNVITDEFNDALVDAIDLLENDH
EHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCCEECCCHHHHHHHHHHHHCCCC
YTSMVIYADGNNFSVGANLFLMKKAHEDGLVDDVVAQSIDKLHYSFNRLKYSLKPVVTAV
CEEEEEEECCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGRALGGGCELVLYSPIVVAASETYIGLVEAGVGLLPSGGGLAEMADRILRTSHKFDDKQ
CCCCCCCCEEEEEECCEEEEECCHHEEHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHH
ASMTKVLTNIAFAKVSTNAFEARRYGYLRDTDTIIFNTAQRVEVALKRAKYEAETNYIPN
HHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCC
PRHQYIALGEDFKALIQGQLDAQRRGHFISDHDYHIALNIATILAGGDLPRNTFINQRYI
CCCCEEEECHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHH
QSLEKIGFIDLLKSKKSYERIAHMLKTGKPLRN
HHHHHCCHHHHHHCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TINKVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLIAKKSYDKITDKKRPLL
CCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEECCCHHHHCCCCCCEE
FDLNLASHLTYGNFDDDLVNDDADLYIEAVKEDIEIKHAVWQQVLQHAKEDALFATNTSG
EEECHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
IPINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSHTKESIILDVKNFAQNVLGKG
CCHHHHHHHHCCCCHHHEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCC
VIVVNDVPGFVANRVGTQTMNDIMYRAEQHKISIVDVDALTGQAIGRPKTGTYALSDLVG
EEEEECCCCHHHHHHCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
LDIAVSVIKGMQQVPEETPYFHDVKIVNTLFDNGALGRKTKQGFYKKDKETKARLVYDVE
HHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCHHHHCCHHCCCCCCEEEEEEEC
KQDYVPVSQPQLPILNEFNKDLVHNLDTIFNAQDEAGLFLWETLRNNFYYSAINVPKATD
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEEECCCCCCH
DFRDIDRALVWGFNWKLGPFQLWDAMGYERVKTRMEDELGDLPQWISDLDGGFYKQDETI
HHHHHHHHHEECCCCCCCHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCE
EYATPISHFVKDELWDKGDAKLSVTHDDQLLLKLQSKNNVITDEFNDALVDAIDLLENDH
EHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEECCCCEECCCHHHHHHHHHHHHCCCC
YTSMVIYADGNNFSVGANLFLMKKAHEDGLVDDVVAQSIDKLHYSFNRLKYSLKPVVTAV
CEEEEEEECCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGRALGGGCELVLYSPIVVAASETYIGLVEAGVGLLPSGGGLAEMADRILRTSHKFDDKQ
CCCCCCCCEEEEEECCEEEEECCHHEEHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHH
ASMTKVLTNIAFAKVSTNAFEARRYGYLRDTDTIIFNTAQRVEVALKRAKYEAETNYIPN
HHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCC
PRHQYIALGEDFKALIQGQLDAQRRGHFISDHDYHIALNIATILAGGDLPRNTFINQRYI
CCCCEEEECHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHH
QSLEKIGFIDLLKSKKSYERIAHMLKTGKPLRN
HHHHHCCHHHHHHCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]