| Definition | Staphylococcus aureus subsp. aureus COL chromosome, complete genome. |
|---|---|
| Accession | NC_002951 |
| Length | 2,809,422 |
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The map label for this gene is mtlR [H]
Identifier: 57652175
GI number: 57652175
Start: 2210386
End: 2212518
Strand: Direct
Name: mtlR [H]
Synonym: SACOL2147
Alternate gene names: 57652175
Gene position: 2210386-2212518 (Clockwise)
Preceding gene: 57652174
Following gene: 57652176
Centisome position: 78.68
GC content: 33.38
Gene sequence:
>2133_bases ATGTTATTGAGTACACGTGAAAAAGAAATGATAGCCCTATTGATTAAGTACCACGGTCAATATATCACTATACACGACAT TGCTCAGCAACTTGCGGTGTCCTCTCGTACTATTCACCGTGAATTAAAAGGTGTTGAAGCATATTTAACTTCATTTTCAT TAACTTTAGAACGCGCAAACAAAAAAGGGCTACGCATTGCTGGCACAGATTCTGATTTAAACGATTTGAAGCAATCGATT GCACAACATCAAACCATTGACTTATCTGTTGAAGAGCAGAAAGTAATTATTATATACGCTTTGATACAAGCCAAGGAGCC AGTTAAACAATATAGTTTAGCGCAAGAAATTGGCGTTTCTGTCCAGACTTTAGCAAAGATGTTAGATGATTTAGAGCTTG ATTTAAATAAGTACCAACTATCTTTATCTCGAAAGCGTGGCGAAGGCATTTACTTGGTAGGTACTGAATCAAAGAAACGT GAATTTTTAAGTCAATTAATGGTGAATAACTTAAATAGTACTAGCGTTTATTCAGTAATTGAAAATCATTTTGTCTTTCA TTCATTAAATCAAATCCACAAAGACTTTGTTGACTTAGAGCGCATTTTTAATGTTGAAAGACTATTAATGGACTACCTAA GTGCCTTACCCTACCAACTTACCGAATCAAGTTATTTAACTTTAACTGTCCATATCGTGCTCTCCATTTCACGTATAAAA AATGGAGAGTATGTCGCATTAAACGATGATATTTATGATTCTGTACAAAACACATTTGAACACAAAGTAGCAAGCGAACT TGCTGATAAACTTGGTCAAATATATGACGTCACGTTTAATCAGGCAGAAATTGCTTTCATTACTATCCATTTACGTGGAG CTAAACGAAAAAATCTTAATGATACATCATTAAATAATCGTTGTGAAGAAAACAAAATTAAAGCGTTTGTTAACAAAGTA GAAATGATTTCCGGTATGACATTTGCAGATTTGGATACTTTAGTAGATGGACTGACGCTACACCTTAATCCTGCAATCAA TCGTTTGCAAGCTAATATCGAGACCTATAATCCGTTAACAGACATGATTAAGTTCAAATATCCAAGACTATTTGAAAATG TAAGATTAGCTTTAAATGATTGTTGGCCTGATTTGATTTTTCCAGAGAGTGAAATTGCTTTTATAGTTTTACACTTTGGT GGCTCGATTAAAAACCAAGGTAATCGATTTTTAAACATATTAGTCGTTTGCAGCAGTGGTATGGGAACTAGTCGTCTATT ATCAACTCGTCTAGAGCAAGTTTTTAGTGAGATTGAGCGTATTACACAAGCATCAGTCAGCGATTTGAAGTCACTAGATT TAAGTCAATATGATGGCATTATTTCTACTGTGAATTTAGACATCGACTCCCCCTATTTAACGGTAAACCCATTATTACCA GATAGTGATATCAGTTATGTCGCACAGTTTTTAAATACAAAGTCTACGTTCCAAGAGACGCATGATAAATCATCAAACAT GATTGATAAGGATGATGTTCATGTTGAAACGAAAGATGTTGATGGCAACACATCTTTTGAAAATGAACAAACTTCATACT TAACTTCAGTTTTCGAAAAACATTTAAGTGACGAAAAATCAGAACAATTATTGCATCATATGCGTTCGGGTTTAACTTTG CTTGATTCAGTGAAAATAGTTAGTACCGAAGTTAAACAGTGGCAAACATATATCGCAGATTATCTATATCAATGCGATGT AATAAACGATCCAACGTCATTCGCTGAACTACTAGAGCAACGATTGATTGACAATCCAGGATGGATATTAAGTCCATATC CTGTTGCAATACCACACCTAAGAGACAATATGATTAAACACCCTATGATTCTAATCACAGTTTTAGAAGAACCGTTAACA TTGCCTAGTATTCAAAATGACAATCAAACAATTAAATATATGATTTCCATGTTTATTTCTGACAATGATTTTATGGCATC ACTGGTAAGTGACTTGTCCGAATTTTTAAGTTTGAAATTAGAATCTATTGATACTTTTATGGAAAATCCACAGGAACTTG AAACATTATTAAGAAACAAATTTTTAGAACGAATTAAAAAACAATTTATTTAG
Upstream 100 bases:
>100_bases AATTTCCTTAATTCACCAAGATATGAAGAACTTTTAAATAATCTAAAAAAAGATGATCAAGCATAATAATTAAATAAATT AAAAAATGGAGGATACCGCC
Downstream 100 bases:
>100_bases GAGTGTACAAAATGAGCGAATTATTTAGTAATGACAATATCTTTTTAAATGTAAATGTTAACAGCCAAAATGAAGCAATT GAAAAAGCAGGTAAAGCCTT
Product: BglG family transcriptional antiterminator
Products: NA
Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 710; Mature: 710
Protein sequence:
>710_residues MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSI AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKR EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKV EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTL LDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLT LPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
Sequences:
>Translated_710_residues MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSI AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKR EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKV EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTL LDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLT LPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI >Mature_710_residues MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSI AQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKR EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKV EMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFG GSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTL LDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLT LPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 81147; Mature: 81147
Theoretical pI: Translated: 4.89; Mature: 4.89
Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERAN CCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC KKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVS CCCCEEECCCCCHHHHHHHHHHCCEEEEEECCCEEEEEEEEHHCCCHHHHHHHHHHHCCC VQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVI HHHHHHHHHHHHCCHHHHHEEEHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHH ENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEHEEHHHHHHCC NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLN CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEEEECCCCCCCC DTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLT CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECHHHHHHHHCCHHCCCHH DMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSG HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEECCC MGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCEEEECCCCC DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEK CCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHH HLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQ HHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH RLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIS HHCCCCCEEECCCCCCCCHHHHHHHCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHC DNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERAN CCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC KKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVS CCCCEEECCCCCHHHHHHHHHHCCEEEEEECCCEEEEEEEEHHCCCHHHHHHHHHHHCCC VQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVI HHHHHHHHHHHHCCHHHHHEEEHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHH ENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEHEEHHHHHHCC NGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLN CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEEEECCCCCCCC DTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLT CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECHHHHHHHHCCHHCCCHH DMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSG HHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEECCC MGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLP CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCEEEECCCCC DSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEK CCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHH HLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQ HHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH RLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIS HHCCCCCEEECCCCCCCCHHHHHHHCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHC DNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]