| Definition | Staphylococcus aureus subsp. aureus COL chromosome, complete genome. |
|---|---|
| Accession | NC_002951 |
| Length | 2,809,422 |
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The map label for this gene is polC [H]
Identifier: 57652115
GI number: 57652115
Start: 2014487
End: 2015041
Strand: Direct
Name: polC [H]
Synonym: SACOL1954
Alternate gene names: 57652115
Gene position: 2014487-2015041 (Clockwise)
Preceding gene: 57652113
Following gene: 57652123
Centisome position: 71.7
GC content: 31.71
Gene sequence:
>555_bases ATGATACAAGATGCGTTTGTTGCACTTGATTTTGAAACAGCAAATGGTAAACGTACAAGTATTTGTTCTGTCGGAATGGT TAAAGTCATTGATAGTCAAATAACAGAAACATTTCATACTCTTGTGAATCCGCAAGACTATTTTTCACAACAAAATATTA AAATTCATGGCATACAACCAGAAGATGTTGAAAATGCACCTACGTTTGACTACGTATTTCCATATATGATGCAATTTATT GCAGATTTACCTGTTGTCGCACATAACGCGGCATTTGATATGAACGTCTTACATCAAAGCATTCAAAATATTGGTTTACC AACTCCAAATTTAACTTACTTTTGTAGTTATCAACTTGCTAAAAGAACCGTTGATTCGTATCGATACGGTTTAAAACATA TGATGGAGTTTTATCAATTAGATTTTCATGGTCATCATGATGCATTGAATGATGCCAAAGCATGCGCAATGATTACTTTT AGGCTACTGAAAAATTATGAAAATTTAACATATGTAACTAATATTTATGGTAAAAATCTAAAAGATAAAGGCTAG
Upstream 100 bases:
>100_bases TTCACGTTATACCTTCACGTATAATATTATGTATCGTTTGTAAGCAAATGACTAAAAGTCTATTAATATATACATTTAAT TAATTGAAAGGATTGACTAC
Downstream 100 bases:
>100_bases GACTAAATAAAATACTCCCTTCAAAAGTAAGCATTGTAAAAATGTAAACTTTGCAGGGAGCTTTATTTTATATAAAGTCA TATATCGTCATATTTTTATA
Product: exonuclease
Products: NA
Alternate protein names: PolIII [H]
Number of amino acids: Translated: 184; Mature: 184
Protein sequence:
>184_residues MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFI ADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITF RLLKNYENLTYVTNIYGKNLKDKG
Sequences:
>Translated_184_residues MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFI ADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITF RLLKNYENLTYVTNIYGKNLKDKG >Mature_184_residues MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFI ADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITF RLLKNYENLTYVTNIYGKNLKDKG
Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]
COG id: COG0847
COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 exonuclease domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011708 - InterPro: IPR006054 - InterPro: IPR006055 - InterPro: IPR013520 - InterPro: IPR023223 - InterPro: IPR016027 - InterPro: IPR004013 - InterPro: IPR003141 - InterPro: IPR006308 - InterPro: IPR012337 [H]
Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 21120; Mature: 21120
Theoretical pI: Translated: 6.29; Mature: 6.29
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 6.0 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 4.3 %Met (Mature Protein) 6.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQP CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECCCC EDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLA CCCCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHHH KRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNL HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCC KDKG CCCC >Mature Secondary Structure MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQP CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECCCC EDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLA CCCCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHHH KRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNL HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCC KDKG CCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11997336 [H]