Definition | Staphylococcus aureus subsp. aureus COL chromosome, complete genome. |
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Accession | NC_002951 |
Length | 2,809,422 |
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The map label for this gene is aroA [H]
Identifier: 57652035
GI number: 57652035
Start: 1831834
End: 1832925
Strand: Reverse
Name: aroA [H]
Synonym: SACOL1787
Alternate gene names: 57652035
Gene position: 1832925-1831834 (Counterclockwise)
Preceding gene: 57652036
Following gene: 57652034
Centisome position: 65.24
GC content: 33.7
Gene sequence:
>1092_bases ATGAGTAATAAATTAGAATCATACAGAAGTGAGATTGTATCACTGAATCATCAAATTTTAGACTTATTATCTAAACGTGG TGAACTAGCACAAAAAATTGGGGAAGAAAAATTAAAACAAGGTACACGTATTTATGATCCACAACGTGAAAAAGAAATGC TTAACGACTTAATCGATAGTAACAAAGGACCATTCAACGATAATACTATTAAGCAATTATTTAAAGAAATTTTCAAAGCC TCTACAGATTTACAAAAATCTGAAAATGAAAAACATTTATATGTATCACGTAAGTTGAAACCTGAAGATACGATTGTAAC ATTTGATAATGGGGGCATTATTGGAGACGGCAATAAATCATTTGTATTTGGGCCATGTTCAGTTGAATCATTTGAACAAG TTGAAGCTGTTGCTAAAAACTTACATGCTAAAGGTGAAAAATTTATTCGTGGCGGTGCATTTAAACCACGTACATCACCA TATGATTTCCAAGGCCTAGGTGTTGAAGGACTTAAAATACTTAAACAGATTAAAGATAAATATGATTTAAATGTTGTCAG CGAAATCGTAAATCCAAATGATTTTGAAGTGGCTGATGAGTATTTAGACGTATTCCAAATTGGTGCACGTAATATGCAAA ACTTCGAGTTATTAAAAGAAGCTGGCCGTACGAAAAAGCCTATTCTATTAAAACGTGGTTTATCTGCTACAATCGAAGAG TTTGTTTATGCAGCTGAATACATTGCTTCACAAGGTAATCAAAACATTATTTTATGTGAACGTGGAATCCGAACTTATGA AAAGGCGACACGTAACACTTTAGATATTTCAGCAGTACCAATTTTAAAACAAGGTACACACTTACCAGTCATGGTAGATG TTACGCATAGTACAGGTCGTAAAGATATCATGTTACCAACTGCGAAAGCAGCATTAGCAGTTGGTGCTGATGGAGTTATG GCTGAGGTGCATCCAGATCCATCTGTTGCACTTAGTGATGCGGGTCAACAAATGGATTTAGATGAATTCCAAGCATTTTA TGATGAATTAAAGCCTTTAGCTGATTTATATAACGCTAAAAAGTTAAAATAA
Upstream 100 bases:
>100_bases GTTGAACTATACATATGATATTGTTAGAATATTTTTTAACATTATATTTTATTGCTTTAAAGTGGAATATACTTGAAATA ATTAGTAGAGGTGAGTAAGG
Downstream 100 bases:
>100_bases TATTCCAAGGAAACTATAGACTACTTAACTAATATGTCATGTTGAAGTAGAATATTATCTTTGAATCGACAATTTTAAAC TTACAGCCATTCTAAGAGTA
Product: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase
Products: NA
Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase [H]
Number of amino acids: Translated: 363; Mature: 362
Protein sequence:
>363_residues MSNKLESYRSEIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDSNKGPFNDNTIKQLFKEIFKA STDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKSFVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSP YDFQGLGVEGLKILKQIKDKYDLNVVSEIVNPNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEE FVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGRKDIMLPTAKAALAVGADGVM AEVHPDPSVALSDAGQQMDLDEFQAFYDELKPLADLYNAKKLK
Sequences:
>Translated_363_residues MSNKLESYRSEIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDSNKGPFNDNTIKQLFKEIFKA STDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKSFVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSP YDFQGLGVEGLKILKQIKDKYDLNVVSEIVNPNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEE FVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGRKDIMLPTAKAALAVGADGVM AEVHPDPSVALSDAGQQMDLDEFQAFYDELKPLADLYNAKKLK >Mature_362_residues SNKLESYRSEIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDSNKGPFNDNTIKQLFKEIFKAS TDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKSFVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSPY DFQGLGVEGLKILKQIKDKYDLNVVSEIVNPNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEEF VYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGRKDIMLPTAKAALAVGADGVMA EVHPDPSVALSDAGQQMDLDEFQAFYDELKPLADLYNAKKLK
Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]
COG id: COG2876
COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 chorismate mutase domain [H]
Homologues:
Organism=Escherichia coli, GI1787466, Length=213, Percent_Identity=26.2910798122066, Blast_Score=83, Evalue=3e-17,
Paralogues:
None
Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013785 - InterPro: IPR002701 - InterPro: IPR010954 - InterPro: IPR020822 - InterPro: IPR006218 - InterPro: IPR006268 [H]
Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1 [H]
EC number: =2.5.1.54; =5.4.99.5 [H]
Molecular weight: Translated: 40619; Mature: 40488
Theoretical pI: Translated: 6.03; Mature: 6.03
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNKLESYRSEIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDS CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC NKGPFNDNTIKQLFKEIFKASTDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKS CCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCCCEEEECCCCEEECCCCC FVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSPYDFQGLGVEGLKILKQIKDK EEECCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH YDLNVVSEIVNPNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEE HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCHHHHHH FVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGR HHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEECCHHHCCCCCCEEEEECCCCCC KDIMLPTAKAALAVGADGVMAEVHPDPSVALSDAGQQMDLDEFQAFYDELKPLADLYNAK CCEECCCHHHHHHCCCCCCEEEECCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC KLK CCC >Mature Secondary Structure SNKLESYRSEIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDS CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC NKGPFNDNTIKQLFKEIFKASTDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKS CCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCCCEEEECCCCEEECCCCC FVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSPYDFQGLGVEGLKILKQIKDK EEECCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH YDLNVVSEIVNPNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEE HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCHHHHHH FVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGR HHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEECCHHHCCCCCCEEEEECCCCCC KDIMLPTAKAALAVGADGVMAEVHPDPSVALSDAGQQMDLDEFQAFYDELKPLADLYNAK CCEECCCHHHHHHCCCCCCEEEECCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC KLK CCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7496534; 9387221; 9384377 [H]