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The map label for this gene is kipI [H]

Identifier: 57652000

GI number: 57652000

Start: 1692825

End: 1693559

Strand: Reverse

Name: kipI [H]

Synonym: SACOL1664

Alternate gene names: 57652000

Gene position: 1693559-1692825 (Counterclockwise)

Preceding gene: 57652001

Following gene: 57651999

Centisome position: 60.28

GC content: 32.93

Gene sequence:

>735_bases
GTGGATGTAAGATTTATTAACGAGCAGACAATTATGATTTATTTTGAAAATAAAATATCCGAAGAGACATATCGTAATGT
CACAGCAATGGTACGGTGGATACGAGAAAAAGAAATATTAGAAATTCAAGATATTGTCCCTTCGTATCGAGCAGTTCTAA
TATATTTTGATGAACAAGCTATAACATCTTCTAAATTAATTGAAAATTTAGAACTTAACAAATTTAATGAAAAAAATGTT
CATGCTGTGAATCAAACCAATCGTATTATTAAAATACCTGTTCAATATGGTGGTACATATGGACCAGATATTGAAGAAGT
AGCAAAGCATAATCGAATAACTGTTGAGCAAGTTATTGAAAAACATACAAGTAAACCTTATTTAATATATATGCTAGGAT
TTATGCCAGGATTTCCATACTTAGGCGGACTTGATGAACAACTACATACACCTAGACGTAATCAGCCAAGGTTAAAAATT
CATGCAGGTTCTGTAGGTATTGCGAATAATCAAACAGGACTATATCCATCAGATTCTCCTGGCGGATGGCAAATTATTGG
ACGCACACCGTTAAAAGTATTTAGCAGCGAGCGTGAACCAATGTCAATGTACGAAGCAGGAGAATGGATACAATTTTATG
CAATAGATGAACAGAAATTTATACAAATCGAAAGAGATATATCAGATGGCAACTTTAATGTTGATGACTGGGTGGTGATT
GAAAATGTCAATTAA

Upstream 100 bases:

>100_bases
GTATGCGATTTGAATTACTTATTAAACAACTTGTGCTTCTCAATGATACAATGAAAAGGTATTCAATACTGGTTTATTGC
AATACAAAGGGGGATTTAAA

Downstream 100 bases:

>100_bases
GATTTTACAACCAGGTCTCTTTTCAACGGTACAAGATCTAGGAAGAATAGGTTATGAACATATTGGATTTTCAGGCGCAG
GTGCCATGGATCAATTTAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAVLIYFDEQAITSSKLIENLELNKFNEKNV
HAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNRITVEQVIEKHTSKPYLIYMLGFMPGFPYLGGLDEQLHTPRRNQPRLKI
HAGSVGIANNQTGLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQKFIQIERDISDGNFNVDDWVVI
ENVN

Sequences:

>Translated_244_residues
MDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAVLIYFDEQAITSSKLIENLELNKFNEKNV
HAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNRITVEQVIEKHTSKPYLIYMLGFMPGFPYLGGLDEQLHTPRRNQPRLKI
HAGSVGIANNQTGLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQKFIQIERDISDGNFNVDDWVVI
ENVN
>Mature_244_residues
MDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAVLIYFDEQAITSSKLIENLELNKFNEKNV
HAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNRITVEQVIEKHTSKPYLIYMLGFMPGFPYLGGLDEQLHTPRRNQPRLKI
HAGSVGIANNQTGLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQKFIQIERDISDGNFNVDDWVVI
ENVN

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786929, Length=208, Percent_Identity=36.5384615384615, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 28350; Mature: 28350

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAVLIYFDEQA
CCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHH
ITSSKLIENLELNKFNEKNVHAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNRITVEQVIE
HHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCEEHHHHHH
KHTSKPYLIYMLGFMPGFPYLGGLDEQLHTPRRNQPRLKIHAGSVGIANNQTGLYPSDSP
HHCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCCEEEEEECCEEECCCCCCCCCCCCC
GGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQKFIQIERDISDGNFNVDDWVVI
CCEEEEECCCHHHHCCCCCCHHHHHCCCEEEEEEECCCEEEEEEECCCCCCCCCCCEEEE
ENVN
EECC
>Mature Secondary Structure
MDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAVLIYFDEQA
CCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHH
ITSSKLIENLELNKFNEKNVHAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNRITVEQVIE
HHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHCCCEEHHHHHH
KHTSKPYLIYMLGFMPGFPYLGGLDEQLHTPRRNQPRLKIHAGSVGIANNQTGLYPSDSP
HHCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCCEEEEEECCEEECCCCCCCCCCCCC
GGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQKFIQIERDISDGNFNVDDWVVI
CCEEEEECCCHHHHCCCCCCHHHHHCCCEEEEEEECCCEEEEEEECCCCCCCCCCCEEEE
ENVN
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]