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The map label for this gene is alr2

Identifier: 57651899

GI number: 57651899

Start: 1446512

End: 1447597

Strand: Direct

Name: alr2

Synonym: SACOL1434

Alternate gene names: 57651899

Gene position: 1446512-1447597 (Clockwise)

Preceding gene: 57651898

Following gene: 57651900

Centisome position: 51.49

GC content: 33.7

Gene sequence:

>1086_bases
TTGACAGCAACATGGTCTGTAAATAAGAAAATATTTTTACAAAATGCAATCACAGTCAAAAACAATCAGCCATTAATGGC
AGTTGTTAAAAATAATGCATATCACTATGACCTAGAATTTGCTGTAACTCAGTTTATCCATGCAGGTATAGATACATTTA
GCACAACATCACTACGAGAAGCAATTCAAATTAGACAACTTGCTCCAGATGCAACAATCTTTTTAATGAATGCAGTTTAC
GAGTTTGATTTAGTCCGTGAACATCAAATACACATGACTTTGCCGTCGTTGACATATTACTATAACCATAAAAATGATTT
AGCTGGTATTCATGTTCACTTAGAATTTGAAAATTTATTACATCGGTCTGGATTTAAAGATTTAAACGAAATTAAAGAAG
TATTGAAAGATCACCATCATAATCAAAATGCAAAAATGATTATTAGTGGTTTATGGACCCATTTTGGATATGCTGATGAA
TTCGATGTGTCAGATTATAATGTTGAACGTTCACAATGGATGGAAATTGTTGAAGCACTTTTATCTGAAGGTTATCAGTT
CGACCTAATCCATGCTCAAAATAGTGCGAGTTTTTATCGGGAAGGACAAATATTACTACCCCACCATACACATGCGCGTG
TAGGTATTGCGTTATACGGTTCAAGACCATATAGTTCACTGAATCAACATGATATAGTTCAGTCATTAACTTTAAAAGCA
CATGTTATTCAAGTGCGCGAAGTACAAGCTGGTGATTATTGCGGTTATAGCTTTGCCTTTGAAGTGACTAAAAACAATAC
AAAATTAGCTGTAGTTGATATCGGTTATGGCGATGGAATTTTAAGAACTCGTGCTAAACATGAAGCACTTATCAATGGTA
AACGCTACCCGATACGTGCATTAATGATGAGCCATATGTTTGTTGAAGTAGATGGCAATGTACATGCACAAGATGAAGTT
ATTCTTTATAATAATGATATCCGCATCGATGAATATACCTTTAAAGGTGTTGGTGCAAATTCTGAACAATTAAGTGCTAT
GAATCATGATTCTTTAAAAAAGGAGTACATTTCAAATGACTGTTAA

Upstream 100 bases:

>100_bases
GGTTTGCACACATCACATTTAAATTTTGATGAAAAAGTGTTAATAAACGTGATTAATTTTTACGAAAATTTATTAAATAA
TTACAAAGAGGTGTAATACA

Downstream 100 bases:

>100_bases
ATATAATCAAAATGGCGAATTAACAATGGATGGTATTAGTTTAAAAACGATTGCACAAAGCTTTGGTACACCTACCATTG
TTTATGATGAACTACAAATT

Product: alanine racemase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTATWSVNKKIFLQNAITVKNNQPLMAVVKNNAYHYDLEFAVTQFIHAGIDTFSTTSLREAIQIRQLAPDATIFLMNAVY
EFDLVREHQIHMTLPSLTYYYNHKNDLAGIHVHLEFENLLHRSGFKDLNEIKEVLKDHHHNQNAKMIISGLWTHFGYADE
FDVSDYNVERSQWMEIVEALLSEGYQFDLIHAQNSASFYREGQILLPHHTHARVGIALYGSRPYSSLNQHDIVQSLTLKA
HVIQVREVQAGDYCGYSFAFEVTKNNTKLAVVDIGYGDGILRTRAKHEALINGKRYPIRALMMSHMFVEVDGNVHAQDEV
ILYNNDIRIDEYTFKGVGANSEQLSAMNHDSLKKEYISNDC

Sequences:

>Translated_361_residues
MTATWSVNKKIFLQNAITVKNNQPLMAVVKNNAYHYDLEFAVTQFIHAGIDTFSTTSLREAIQIRQLAPDATIFLMNAVY
EFDLVREHQIHMTLPSLTYYYNHKNDLAGIHVHLEFENLLHRSGFKDLNEIKEVLKDHHHNQNAKMIISGLWTHFGYADE
FDVSDYNVERSQWMEIVEALLSEGYQFDLIHAQNSASFYREGQILLPHHTHARVGIALYGSRPYSSLNQHDIVQSLTLKA
HVIQVREVQAGDYCGYSFAFEVTKNNTKLAVVDIGYGDGILRTRAKHEALINGKRYPIRALMMSHMFVEVDGNVHAQDEV
ILYNNDIRIDEYTFKGVGANSEQLSAMNHDSLKKEYISNDC
>Mature_360_residues
TATWSVNKKIFLQNAITVKNNQPLMAVVKNNAYHYDLEFAVTQFIHAGIDTFSTTSLREAIQIRQLAPDATIFLMNAVYE
FDLVREHQIHMTLPSLTYYYNHKNDLAGIHVHLEFENLLHRSGFKDLNEIKEVLKDHHHNQNAKMIISGLWTHFGYADEF
DVSDYNVERSQWMEIVEALLSEGYQFDLIHAQNSASFYREGQILLPHHTHARVGIALYGSRPYSSLNQHDIVQSLTLKAH
VIQVREVQAGDYCGYSFAFEVTKNNTKLAVVDIGYGDGILRTRAKHEALINGKRYPIRALMMSHMFVEVDGNVHAQDEVI
LYNNDIRIDEYTFKGVGANSEQLSAMNHDSLKKEYISNDC

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR2_STAA8 (Q9EZ08)

Other databases:

- EMBL:   AF306669
- EMBL:   CP000253
- RefSeq:   YP_499927.1
- ProteinModelPortal:   Q9EZ08
- SMR:   Q9EZ08
- STRING:   Q9EZ08
- EnsemblBacteria:   EBSTAT00000029769
- GeneID:   3920690
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_01400
- eggNOG:   COG0787
- GeneTree:   EBGT00050000023673
- HOGENOM:   HBG712172
- OMA:   AYHYGLE
- ProtClustDB:   CLSK885326
- BioCyc:   SAUR93061:SAOUHSC_01400-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 41410; Mature: 41279

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 30-30 ACT_SITE 256-256

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATWSVNKKIFLQNAITVKNNQPLMAVVKNNAYHYDLEFAVTQFIHAGIDTFSTTSLRE
CCCEEECCCEEEEEEEEEEECCCCEEEEEECCCEEEEHHHHHHHHHHHCCCCCCHHHHHH
AIQIRQLAPDATIFLMNAVYEFDLVREHQIHMTLPSLTYYYNHKNDLAGIHVHLEFENLL
HHHHHHCCCCCEEEEEHHHHHHHHEEEEEEEEEECCEEEEECCCCCEEEEEEEEEHHHHH
HRSGFKDLNEIKEVLKDHHHNQNAKMIISGLWTHFGYADEFDVSDYNVERSQWMEIVEAL
HHCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LSEGYQFDLIHAQNSASFYREGQILLPHHTHARVGIALYGSRPYSSLNQHDIVQSLTLKA
HHCCCEEEEEEECCCCCHHHCCCEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHEE
HVIQVREVQAGDYCGYSFAFEVTKNNTKLAVVDIGYGDGILRTRAKHEALINGKRYPIRA
EEEEEEEECCCCCCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHH
LMMSHMFVEVDGNVHAQDEVILYNNDIRIDEYTFKGVGANSEQLSAMNHDSLKKEYISND
HHHHEEEEEECCCEECCCEEEEEECCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHCCC
C
C
>Mature Secondary Structure 
TATWSVNKKIFLQNAITVKNNQPLMAVVKNNAYHYDLEFAVTQFIHAGIDTFSTTSLRE
CCEEECCCEEEEEEEEEEECCCCEEEEEECCCEEEEHHHHHHHHHHHCCCCCCHHHHHH
AIQIRQLAPDATIFLMNAVYEFDLVREHQIHMTLPSLTYYYNHKNDLAGIHVHLEFENLL
HHHHHHCCCCCEEEEEHHHHHHHHEEEEEEEEEECCEEEEECCCCCEEEEEEEEEHHHHH
HRSGFKDLNEIKEVLKDHHHNQNAKMIISGLWTHFGYADEFDVSDYNVERSQWMEIVEAL
HHCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
LSEGYQFDLIHAQNSASFYREGQILLPHHTHARVGIALYGSRPYSSLNQHDIVQSLTLKA
HHCCCEEEEEEECCCCCHHHCCCEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHEE
HVIQVREVQAGDYCGYSFAFEVTKNNTKLAVVDIGYGDGILRTRAKHEALINGKRYPIRA
EEEEEEEECCCCCCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHH
LMMSHMFVEVDGNVHAQDEVILYNNDIRIDEYTFKGVGANSEQLSAMNHDSLKKEYISND
HHHHEEEEEECCCEECCCEEEEEECCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHCCC
C
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11447207