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The map label for this gene is dapA [H]

Identifier: 57651895

GI number: 57651895

Start: 1442861

End: 1443748

Strand: Direct

Name: dapA [H]

Synonym: SACOL1430

Alternate gene names: 57651895

Gene position: 1442861-1443748 (Clockwise)

Preceding gene: 57651894

Following gene: 57651896

Centisome position: 51.36

GC content: 35.7

Gene sequence:

>888_bases
ATGACACATTTATTTGAGGGTGTTGGCGTTGCACTTACAACCCCTTTTACAAATAACAAAGTTAATATTGAAGCTTTGAA
AACACACGTTAATTTTTTACTAGAAAATAATGCCCAAGCAATCATCGTTAATGGAACTACTGCTGAGAGCCCTACTTTAA
CAACAGATGAAAAAGAACGCATTCTAAAAACAGTTATTGATCTTGTAGATAAACGTGTTCCTGTCATAGCAGGAACTGGC
ACTAATGATACTGAAAAGTCAATCCAAGCTTCAATCCAAGCTAAAGCCTTAGGGGCTGATGCAATTATGTTAATTACGCC
CTACTACAACAAAACGAACCAACGTGGTTTAGTCAAACACTTTGAAGCGATTGCAGATGCTGTGAAATTACCAGTCGTGC
TGTACAATGTTCCTTCAAGAACGAACATGACAATTGAACCAGAAACTGTAGAAATATTAAGTCAACATCCTTATATAGTT
GCTTTAAAAGATGCTACGAATGATTTTGAGTATTTAGAAGAAGTGAAAAAGCGCATTGATACAAATTCATTTGCATTATA
TAGTGGCAATGATGACAACGTCGTCGAATACTATCAACGTGGCGGTCAAGGGGTTATCTCTGTTATTGCCAATGTCATTC
CTAAAGAATTTCAAGCGTTATACGATGCTCAACAAAGTGGATTAGATATTCAAGATCAATTTAAACCAATCGGCACACTG
TTATCAGCTTTATCAGTTGATATTAACCCAATTCCTATTAAAGCTCTAACAAGTTATTTAGGATTTGGAAATTATGAATT
ACGTCTACCATTGGTTAGCCTAGAAGATACAGATACTAAAGTGCTTCGTGAAACATATGACACATTTAAAGCGGGTGAAA
ATGAGTGA

Upstream 100 bases:

>100_bases
TTCCATGTATGGTGTACATCAGACAATTTATTAAAAGGTGCTGCATTAAATGCTGTACAAGTATTGGAACAAGTTATGCG
TTTAAAAGGAGCGAATTAAA

Downstream 100 bases:

>100_bases
AAATATTACTAATTGGCTATGGCGCAATGAATCAACGCGTTGCTAGATTAGCAGAAGAAAAAGGACATGAAATCGTTGGG
GTCATTGAAAATACACCGAA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTHLFEGVGVALTTPFTNNKVNIEALKTHVNFLLENNAQAIIVNGTTAESPTLTTDEKERILKTVIDLVDKRVPVIAGTG
TNDTEKSIQASIQAKALGADAIMLITPYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIV
ALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTL
LSALSVDINPIPIKALTSYLGFGNYELRLPLVSLEDTDTKVLRETYDTFKAGENE

Sequences:

>Translated_295_residues
MTHLFEGVGVALTTPFTNNKVNIEALKTHVNFLLENNAQAIIVNGTTAESPTLTTDEKERILKTVIDLVDKRVPVIAGTG
TNDTEKSIQASIQAKALGADAIMLITPYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIV
ALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTL
LSALSVDINPIPIKALTSYLGFGNYELRLPLVSLEDTDTKVLRETYDTFKAGENE
>Mature_294_residues
THLFEGVGVALTTPFTNNKVNIEALKTHVNFLLENNAQAIIVNGTTAESPTLTTDEKERILKTVIDLVDKRVPVIAGTGT
NDTEKSIQASIQAKALGADAIMLITPYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIVA
LKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTLL
SALSVDINPIPIKALTSYLGFGNYELRLPLVSLEDTDTKVLRETYDTFKAGENE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=283, Percent_Identity=26.1484098939929, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI13540533, Length=228, Percent_Identity=27.6315789473684, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1788823, Length=290, Percent_Identity=36.2068965517241, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI87082415, Length=227, Percent_Identity=30.3964757709251, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786463, Length=228, Percent_Identity=30.7017543859649, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789620, Length=229, Percent_Identity=27.5109170305677, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32584; Mature: 32453

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLFEGVGVALTTPFTNNKVNIEALKTHVNFLLENNAQAIIVNGTTAESPTLTTDEKER
CCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHEEECCCCEEEEECCCCCCCCCCCCHHHH
ILKTVIDLVDKRVPVIAGTGTNDTEKSIQASIQAKALGADAIMLITPYYNKTNQRGLVKH
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHH
FEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIVALKDATNDFEYLEEVKKRID
HHHHHHHHHCCEEEEECCCCCCEEECCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCC
TNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTL
CCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LSALSVDINPIPIKALTSYLGFGNYELRLPLVSLEDTDTKVLRETYDTFKAGENE
HHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
THLFEGVGVALTTPFTNNKVNIEALKTHVNFLLENNAQAIIVNGTTAESPTLTTDEKER
CCCCCCCCEEEECCCCCCEEEHHHHHHHHHHEEECCCCEEEEECCCCCCCCCCCCHHHH
ILKTVIDLVDKRVPVIAGTGTNDTEKSIQASIQAKALGADAIMLITPYYNKTNQRGLVKH
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHH
FEAIADAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIVALKDATNDFEYLEEVKKRID
HHHHHHHHHCCEEEEECCCCCCEEECCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCC
TNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTL
CCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LSALSVDINPIPIKALTSYLGFGNYELRLPLVSLEDTDTKVLRETYDTFKAGENE
HHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA