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The map label for this gene is asd [H]

Identifier: 57651894

GI number: 57651894

Start: 1441870

End: 1442859

Strand: Direct

Name: asd [H]

Synonym: SACOL1429

Alternate gene names: 57651894

Gene position: 1441870-1442859 (Clockwise)

Preceding gene: 57651893

Following gene: 57651895

Centisome position: 51.32

GC content: 35.66

Gene sequence:

>990_bases
ATGACAAAGTTAGCAGTTGTGGGTGCAACAGGATTAGTAGGTACAAAAATGTTGGAGACATTAAATCGTAAAAATATTCC
TTTCGATGAATTAGTATTATTTTCATCAGCACGTTCTGCAGGGCAAGAAGTTGAATTTCAAGGAAAAACATATACAGTTC
AAGAATTAACTGATGCTCGTGCAAGTGAACATTTCGATTATGTATTAATGAGTGCTGGTGGCGGTACAAGCGAACACTTT
GCCCCACTTTTTGAAAAAGCTGGTGCAATCGTTATAGACAATTCAAGTCAATGGCGTATGGCAGAAGATATTGATTTAAT
CGTTCCGGAAGTCAATGAACCTACATTTACAAGAGGTATCATTGCCAATCCAAACTGCTCTACGATTCAATCTGTTGTAC
CTCTAAAAGTATTGCAAGATGCTTATGGTTTAAAACGAGTGGCATATACAACATATCAAGCTGTATCAGGTTCAGGGATG
AAAGGTAAGAAAGATTTAGCTGAAGGTGTAAATGGTAAAGCACCAGAAGCATATCCACATCCAATTTATAATAATGTGTT
ACCGCATATTGATGTGTTTTTAGAAAACGGATATACAAAAGAAGAACAAAAAATGATTGATGAGACGAGAAAAATTTTAA
ATGCGCCAGACTTAAAAGTAACAGCAACATGCGCACGTGTGCCTGTTCAAGATAGTCATAGTGTTGAAATTGATGTAACG
CTTGACAAAGAAACAACAGCAGAAGATATTAAAGCGTTATTTGATCAAGATGACCGCGTTGTTTTAGTAGACAATCCAGA
GAACAATGAATATCCAATGGCAATCAATTCTACTAATAAAGATGAAGTGTTTGTTGGCCGTATACGTAGAGATGATTCAT
TAGAAAATACTTTCCATGTATGGTGTACATCAGACAATTTATTAAAAGGTGCTGCATTAAATGCTGTACAAGTATTGGAA
CAAGTTATGCGTTTAAAAGGAGCGAATTAA

Upstream 100 bases:

>100_bases
AGCGGTAGAAAAACTATATGACGCATTTAACATTTAATGGTAAAATGATTGTTAAAATATTCTAAAAATTGGAAATTATT
ATAAAATGGAGTGACAAGTT

Downstream 100 bases:

>100_bases
AATGACACATTTATTTGAGGGTGTTGGCGTTGCACTTACAACCCCTTTTACAAATAACAAAGTTAATATTGAAGCTTTGA
AAACACACGTTAATTTTTTA

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTKLAVVGATGLVGTKMLETLNRKNIPFDELVLFSSARSAGQEVEFQGKTYTVQELTDARASEHFDYVLMSAGGGTSEHF
APLFEKAGAIVIDNSSQWRMAEDIDLIVPEVNEPTFTRGIIANPNCSTIQSVVPLKVLQDAYGLKRVAYTTYQAVSGSGM
KGKKDLAEGVNGKAPEAYPHPIYNNVLPHIDVFLENGYTKEEQKMIDETRKILNAPDLKVTATCARVPVQDSHSVEIDVT
LDKETTAEDIKALFDQDDRVVLVDNPENNEYPMAINSTNKDEVFVGRIRRDDSLENTFHVWCTSDNLLKGAALNAVQVLE
QVMRLKGAN

Sequences:

>Translated_329_residues
MTKLAVVGATGLVGTKMLETLNRKNIPFDELVLFSSARSAGQEVEFQGKTYTVQELTDARASEHFDYVLMSAGGGTSEHF
APLFEKAGAIVIDNSSQWRMAEDIDLIVPEVNEPTFTRGIIANPNCSTIQSVVPLKVLQDAYGLKRVAYTTYQAVSGSGM
KGKKDLAEGVNGKAPEAYPHPIYNNVLPHIDVFLENGYTKEEQKMIDETRKILNAPDLKVTATCARVPVQDSHSVEIDVT
LDKETTAEDIKALFDQDDRVVLVDNPENNEYPMAINSTNKDEVFVGRIRRDDSLENTFHVWCTSDNLLKGAALNAVQVLE
QVMRLKGAN
>Mature_328_residues
TKLAVVGATGLVGTKMLETLNRKNIPFDELVLFSSARSAGQEVEFQGKTYTVQELTDARASEHFDYVLMSAGGGTSEHFA
PLFEKAGAIVIDNSSQWRMAEDIDLIVPEVNEPTFTRGIIANPNCSTIQSVVPLKVLQDAYGLKRVAYTTYQAVSGSGMK
GKKDLAEGVNGKAPEAYPHPIYNNVLPHIDVFLENGYTKEEQKMIDETRKILNAPDLKVTATCARVPVQDSHSVEIDVTL
DKETTAEDIKALFDQDDRVVLVDNPENNEYPMAINSTNKDEVFVGRIRRDDSLENTFHVWCTSDNLLKGAALNAVQVLEQ
VMRLKGAN

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=29.8816568047337, Blast_Score=144, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6320362, Length=382, Percent_Identity=28.0104712041885, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36283; Mature: 36152

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLAVVGATGLVGTKMLETLNRKNIPFDELVLFSSARSAGQEVEFQGKTYTVQELTDAR
CCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCEEEHHHHHHHH
ASEHFDYVLMSAGGGTSEHFAPLFEKAGAIVIDNSSQWRMAEDIDLIVPEVNEPTFTRGI
HHCCCCEEEEECCCCCCHHHHHHHHHCCEEEEECCCCCEECCCCEEEECCCCCCCCCCCE
IANPNCSTIQSVVPLKVLQDAYGLKRVAYTTYQAVSGSGMKGKKDLAEGVNGKAPEAYPH
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
PIYNNVLPHIDVFLENGYTKEEQKMIDETRKILNAPDLKVTATCARVPVQDSHSVEIDVT
CHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEE
LDKETTAEDIKALFDQDDRVVLVDNPENNEYPMAINSTNKDEVFVGRIRRDDSLENTFHV
ECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCCCEEEEEECCCCCCCCEEEE
WCTSDNLLKGAALNAVQVLEQVMRLKGAN
EECCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKLAVVGATGLVGTKMLETLNRKNIPFDELVLFSSARSAGQEVEFQGKTYTVQELTDAR
CEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCEEEHHHHHHHH
ASEHFDYVLMSAGGGTSEHFAPLFEKAGAIVIDNSSQWRMAEDIDLIVPEVNEPTFTRGI
HHCCCCEEEEECCCCCCHHHHHHHHHCCEEEEECCCCCEECCCCEEEECCCCCCCCCCCE
IANPNCSTIQSVVPLKVLQDAYGLKRVAYTTYQAVSGSGMKGKKDLAEGVNGKAPEAYPH
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
PIYNNVLPHIDVFLENGYTKEEQKMIDETRKILNAPDLKVTATCARVPVQDSHSVEIDVT
CHHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEEE
LDKETTAEDIKALFDQDDRVVLVDNPENNEYPMAINSTNKDEVFVGRIRRDDSLENTFHV
ECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCCCEEEEEECCCCCCCCEEEE
WCTSDNLLKGAALNAVQVLEQVMRLKGAN
EECCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]