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The map label for this gene is yaeL [C]

Identifier: 57651832

GI number: 57651832

Start: 1290026

End: 1291312

Strand: Direct

Name: yaeL [C]

Synonym: SACOL1281

Alternate gene names: 57651832

Gene position: 1290026-1291312 (Clockwise)

Preceding gene: 57651831

Following gene: 57651833

Centisome position: 45.92

GC content: 33.26

Gene sequence:

>1287_bases
GTGAGCTATTTAGTTACAATAATTGCATTTATTATTGTTTTTGGTGTACTAGTAACTGTTCATGAATATGGCCATATGTT
TTTTGCGAAAAGAGCAGGCATTATGTGTCCAGAATTTGCGATCGGTATGGGGCCAAAAATTTTTAGTTTTAGAAAAAATG
AAACACTTTACACTATTAGGTTATTGCCTGTTGGTGGATATGTTCGTATGGCAGGAGATGGCTTAGAAGAGCCACCAGTC
GAGCCCGGTATGAACGTTAAAATTAAACTTAATGAAGAAAATGAAATAACACATATCATATTAGATGATCATCATAAGTT
TCAACAAATTGAAGCGATCGAAGTTAAAAAATGTGATTTTAAGGATGACTTATTCATAGAAGGTATCACTGCTTATGATA
ATGAAAGACATCATTTTAAAATTGCTAGAAAGTCTTTCTTTGTTGAAAATGGTAGCTTAGTTCAAATTGCTCCGAGAGAC
AGACAATTTGCACATAAAAAGCCATGGCCGAAATTTTTAACATTATTTGCGGGACCGTTATTTAACTTTATATTAGCTTT
AGTCCTATTTATTGGTCTTGCATATTATCAAGGCACGCCTACGTCTACTGTAGAACAAGTCGCAGATAAGTATCCAGCTC
AACAAGCAGGATTACAAAAAGGTGATAAGATCGTCCAAATTGGCAAATATAAAATATCTGAATTTGATGATGTTGATAAG
GCGTTAGATAAAGTTAAAGATAATAAGACGACTGTTAAATTTGAACGTGATGGTAAAACAAAGTCAGTTGAATTAACACC
TAAAAAGACTGAAAAAAAACTGACTAAAGTAAGTTCAGAGACGAAGTATGTTCTCGGATTCCAACCAGCGAGTGAACATA
CACTTTTTAAACCAATTGTATTCGGATTTAAAAGCTTTTTAATCGGTAGTACTTATATTTTTACAGCTGTAGTAGGTATG
TTGGCTAGTATATTTACGGGCGGATTCTCATTTGATATGTTAAATGGTCCGGTTGGTATTTATCATAACGTCGACTCAGT
TGTTAAAGCGGGTATCATTAGCTTAATTGGTTACACTGCGTTATTAAGTGTAAACTTAGGTATTATGAATTTAATTCCTA
TTCCTGCACTAGACGGTGGTCGTATTTTATTTGTTATATATGAAGCGATTTTCAGAAAACCAGTTAATAAAAAAGCGGAA
ACAACGATTATTGCTATTGGTGCCATTTTCATGGTCGTTATAATGATATTAGTAACGTGGAATGATATTCGACGATATTT
CTTATAA

Upstream 100 bases:

>100_bases
ATTTTGTGATTTGTCAGTATCATATTATAATGACTTATGTTACGTATACAGCAATCATTTTTAAAATAAAAGAAATTTAT
AAACAATCGAGGTGTAGCGA

Downstream 100 bases:

>100_bases
TTTAGGAGGATAAATAATTATGAAGCAATCCAAAGTTTTTATACCAACGATGCGTGACGTGCCATCAGAAGCAGAAGCAC
AAAGTCATCGTTTATTATTG

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPV
EPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRD
RQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDK
ALDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIVFGFKSFLIGSTYIFTAVVGM
LASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAE
TTIIAIGAIFMVVIMILVTWNDIRRYFL

Sequences:

>Translated_428_residues
MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPV
EPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRD
RQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDK
ALDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIVFGFKSFLIGSTYIFTAVVGM
LASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAE
TTIIAIGAIFMVVIMILVTWNDIRRYFL
>Mature_427_residues
SYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVE
PGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDR
QFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDKA
LDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIVFGFKSFLIGSTYIFTAVVGML
ASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAET
TIIAIGAIFMVVIMILVTWNDIRRYFL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=234, Percent_Identity=28.6324786324786, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48107; Mature: 47976

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHEEEECCCEEEEEE
LLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDF
EEECCCEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHEEEEECCCC
KDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPL
CCCEEEEEEECCCCCCHHEEEEHHHEEEECCCEEEECCCCCHHCCCCCCHHHHHHHHHHH
FNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCCCCEEEECCEECCCHHHHHH
ALDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIV
HHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHH
FGFKSFLIGSTYIFTAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHH
LLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTW
HHHHCCCHHEEECCCCCCCCEEHHHHHHHHHCCCCCCCHHHHEEHHHHHHHHHHHHHHHH
NDIRRYFL
HHHHHHCC
>Mature Secondary Structure 
SYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHEEEECCCEEEEEE
LLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDF
EEECCCEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHEEEEECCCC
KDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPL
CCCEEEEEEECCCCCCHHEEEEHHHEEEECCCEEEECCCCCHHCCCCCCHHHHHHHHHHH
FNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCCCCEEEECCEECCCHHHHHH
ALDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIV
HHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHH
FGFKSFLIGSTYIFTAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHH
LLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTW
HHHHCCCHHEEECCCCCCCCEEHHHHHHHHHCCCCCCCHHHHEEHHHHHHHHHHHHHHHH
NDIRRYFL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]