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The map label for this gene is ycsN [H]

Identifier: 57651529

GI number: 57651529

Start: 769568

End: 770476

Strand: Direct

Name: ycsN [H]

Synonym: SACOL0748

Alternate gene names: 57651529

Gene position: 769568-770476 (Clockwise)

Preceding gene: 57651528

Following gene: 57651530

Centisome position: 27.39

GC content: 33.77

Gene sequence:

>909_bases
ATGGAACAAATAATGATTAATCACTATGTTCATTTTTCTAGGCTTGTACAAGGTTTTTGGCGTGCAAATGAATGGAAGAT
GACTGCGAAAGAGTTAAATTATTTTATAAATGAATTAGTTGAACGTGGAATTACAACGATGGATCATGCTGATATTTATG
GAGATTATCAATGTGAATCACTGTTTGGTAATGCTTTGGATTTATCACCCGAATTAAGAAATAAAATTCAAATTGTTACG
AAATGTGGTATCATTTTGCCTTCTAAGCAATTTGATTTTACAAATGGACATCGTTATGATTTGAGTAGTAAGCACATCGT
GAAATCTGTTGAACAGTCATTAATCAATTTGAATGTAGATTATTTAGATAGTCTACTCATTCATCGTCCTTCACCATTGA
TGGATCCAGAACAAGTTGCTGATGCATTAACTAAACTTGTTAAACAAGGTAAGTTGAAGTCATTCGGGGTGTCGAATTTT
AATCATTCACAATACCAATTGTTAAATCAATATATTATGAAAGAAAGACTACATATTAGCATCAATCAATTAGAATTATC
GCCATATCACGTTGATAGTTTACAAGATGGAACAATGGATTCAATGTATCAAAACCATGTTCAAATCATGGCTTGGAGTC
CTTTTGCAGGCGGTAAAATTTTCGACAAGGAAGATATTAAAGCGCAACGTATTATGAAAGTTGTTCAATCAATAGCTGAC
AAATATGGTGTGAGTGACACAGCTGTGATGATAGCGTGGTTAGTAAAAATACCGCATCGTATCATGCCGATACTTGGAAC
AAGTCAGTTAAAGCGTATTGATCAAGCAATCGAAGGGCTACAACTTAATTTAGATGATCAGTCGTGGTTTGACATTTACA
CCGCTATTATCGGACAAGATATTCCGTAA

Upstream 100 bases:

>100_bases
CAGAAAATGTGTTGTTTCAATTTAACGGAAATAGCACATTAATTTCTTAATACTTTTATTGTGAATATTTTGTGACATTG
AGGGATGGAGTGGATGAGAT

Downstream 100 bases:

>100_bases
ACTTATTTACTTTTAAATCATAAAGGAGCATATCATGACAAACGAAGATAAACGTTTCGAACAATTAAGATTTGAACGCA
AATTTATAGTTATTCCGTAT

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MEQIMINHYVHFSRLVQGFWRANEWKMTAKELNYFINELVERGITTMDHADIYGDYQCESLFGNALDLSPELRNKIQIVT
KCGIILPSKQFDFTNGHRYDLSSKHIVKSVEQSLINLNVDYLDSLLIHRPSPLMDPEQVADALTKLVKQGKLKSFGVSNF
NHSQYQLLNQYIMKERLHISINQLELSPYHVDSLQDGTMDSMYQNHVQIMAWSPFAGGKIFDKEDIKAQRIMKVVQSIAD
KYGVSDTAVMIAWLVKIPHRIMPILGTSQLKRIDQAIEGLQLNLDDQSWFDIYTAIIGQDIP

Sequences:

>Translated_302_residues
MEQIMINHYVHFSRLVQGFWRANEWKMTAKELNYFINELVERGITTMDHADIYGDYQCESLFGNALDLSPELRNKIQIVT
KCGIILPSKQFDFTNGHRYDLSSKHIVKSVEQSLINLNVDYLDSLLIHRPSPLMDPEQVADALTKLVKQGKLKSFGVSNF
NHSQYQLLNQYIMKERLHISINQLELSPYHVDSLQDGTMDSMYQNHVQIMAWSPFAGGKIFDKEDIKAQRIMKVVQSIAD
KYGVSDTAVMIAWLVKIPHRIMPILGTSQLKRIDQAIEGLQLNLDDQSWFDIYTAIIGQDIP
>Mature_302_residues
MEQIMINHYVHFSRLVQGFWRANEWKMTAKELNYFINELVERGITTMDHADIYGDYQCESLFGNALDLSPELRNKIQIVT
KCGIILPSKQFDFTNGHRYDLSSKHIVKSVEQSLINLNVDYLDSLLIHRPSPLMDPEQVADALTKLVKQGKLKSFGVSNF
NHSQYQLLNQYIMKERLHISINQLELSPYHVDSLQDGTMDSMYQNHVQIMAWSPFAGGKIFDKEDIKAQRIMKVVQSIAD
KYGVSDTAVMIAWLVKIPHRIMPILGTSQLKRIDQAIEGLQLNLDDQSWFDIYTAIIGQDIP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=302, Percent_Identity=22.5165562913907, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4504825, Length=302, Percent_Identity=22.5165562913907, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27436962, Length=271, Percent_Identity=21.0332103321033, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI27436964, Length=271, Percent_Identity=21.0332103321033, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI27436966, Length=271, Percent_Identity=21.0332103321033, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI48994888, Length=291, Percent_Identity=43.9862542955326, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87081735, Length=293, Percent_Identity=22.5255972696246, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788081, Length=291, Percent_Identity=27.4914089347079, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082198, Length=248, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786400, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788070, Length=272, Percent_Identity=23.8970588235294, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789375, Length=268, Percent_Identity=22.7611940298507, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17538386, Length=267, Percent_Identity=26.5917602996255, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320079, Length=255, Percent_Identity=25.0980392156863, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34777; Mature: 34777

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQIMINHYVHFSRLVQGFWRANEWKMTAKELNYFINELVERGITTMDHADIYGDYQCES
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCHHH
LFGNALDLSPELRNKIQIVTKCGIILPSKQFDFTNGHRYDLSSKHIVKSVEQSLINLNVD
HCCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
YLDSLLIHRPSPLMDPEQVADALTKLVKQGKLKSFGVSNFNHSQYQLLNQYIMKERLHIS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEE
INQLELSPYHVDSLQDGTMDSMYQNHVQIMAWSPFAGGKIFDKEDIKAQRIMKVVQSIAD
EEEEEECCEECCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KYGVSDTAVMIAWLVKIPHRIMPILGTSQLKRIDQAIEGLQLNLDDQSWFDIYTAIIGQD
HHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCC
IP
CC
>Mature Secondary Structure
MEQIMINHYVHFSRLVQGFWRANEWKMTAKELNYFINELVERGITTMDHADIYGDYQCES
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCHHH
LFGNALDLSPELRNKIQIVTKCGIILPSKQFDFTNGHRYDLSSKHIVKSVEQSLINLNVD
HCCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
YLDSLLIHRPSPLMDPEQVADALTKLVKQGKLKSFGVSNFNHSQYQLLNQYIMKERLHIS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEE
INQLELSPYHVDSLQDGTMDSMYQNHVQIMAWSPFAGGKIFDKEDIKAQRIMKVVQSIAD
EEEEEECCEECCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KYGVSDTAVMIAWLVKIPHRIMPILGTSQLKRIDQAIEGLQLNLDDQSWFDIYTAIIGQD
HHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCC
IP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]