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The map label for this gene is yciC [H]

Identifier: 57651528

GI number: 57651528

Start: 768539

End: 769465

Strand: Direct

Name: yciC [H]

Synonym: SACOL0747

Alternate gene names: 57651528

Gene position: 768539-769465 (Clockwise)

Preceding gene: 57651526

Following gene: 57651529

Centisome position: 27.36

GC content: 31.07

Gene sequence:

>927_bases
ATGAAAAATAATAAAGATGAAAAAATAAGAATATCCATAATTAACGGATTTTTGGGTAGTGGTAAAACCACGTTACTGAC
ACATTATATTAGTGAATTATTAAAAAATGATGAGAAAATTAAAATCATCATGAATGAATTCGGTACTTTTGATATTGATA
GCAATAGTATTTCAAATGAAATTGAAGTCCATTCATTGATTAATGGTTGTGTTTGTTGCGATCTTAAACAAGAACTTGTC
TATGAACTAAAAGCCATTGCTTTAAAAGGGGACGTTAATCATGTCATCATAGAAGCGACAGGCATTGCGCATCCTTTGGA
ATTACTAGTTGCATGTCAAGATCCGCAAATCGTTAATTTCTTTGAAAAGCCGATTATTTATGGTGTATTAGATGCGACTC
GATTTTTAGAACGTCATCAATATACCGAAAATACAGTTTCGCTGATGGAAGATCAGTTGAAACTAAGTGACATGATTATT
ATTAATAAAATTGATCTTATAACTGATGACAGTCTTGAGAAAATTGATAAGCAATTAGGTATGATTTGTGCAAGTATTCC
AACTTATAAAACAACCTATGGAAAAGTTTCGTTGGAAGAATTGGACTTAACTGTTAAAGACAGAGAGATATCGTCTCATC
ATCACCATCATCATGGGATTAAAAGTATGACTTACACGTTTACAGGTCCGATTGATCGTCATTTGTTTTATCAATTTATA
ATGAAATTACCGGAATCTGTTCTACGTTTGAAAGGTTATGTGTCATTTAGAGATCAACCAAATGCAATTTATGAATTTCA
ATATGCATATGGTTTACCAGACTATGGAATAATTGGCATGCAATTACCATTAACGATTGTTATTATTGGTGAAACTTTAG
ATACAAATCACATACGTAATCAATTGGATATGCTACAATTTACGTAA

Upstream 100 bases:

>100_bases
TAAAGTTTAGAAGATATTTTTGATTAAATCAAGCAAAAAGATAATTTAATATATATGTTATCATTTTTAAAAATAACTGT
AATAGAAAAGAGAATATAAA

Downstream 100 bases:

>100_bases
ATCAGAAAATGTGTTGTTTCAATTTAACGGAAATAGCACATTAATTTCTTAATACTTTTATTGTGAATATTTTGTGACAT
TGAGGGATGGAGTGGATGAG

Product: cobalamin synthesis protein/P47K family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKNNKDEKIRISIINGFLGSGKTTLLTHYISELLKNDEKIKIIMNEFGTFDIDSNSISNEIEVHSLINGCVCCDLKQELV
YELKAIALKGDVNHVIIEATGIAHPLELLVACQDPQIVNFFEKPIIYGVLDATRFLERHQYTENTVSLMEDQLKLSDMII
INKIDLITDDSLEKIDKQLGMICASIPTYKTTYGKVSLEELDLTVKDREISSHHHHHHGIKSMTYTFTGPIDRHLFYQFI
MKLPESVLRLKGYVSFRDQPNAIYEFQYAYGLPDYGIIGMQLPLTIVIIGETLDTNHIRNQLDMLQFT

Sequences:

>Translated_308_residues
MKNNKDEKIRISIINGFLGSGKTTLLTHYISELLKNDEKIKIIMNEFGTFDIDSNSISNEIEVHSLINGCVCCDLKQELV
YELKAIALKGDVNHVIIEATGIAHPLELLVACQDPQIVNFFEKPIIYGVLDATRFLERHQYTENTVSLMEDQLKLSDMII
INKIDLITDDSLEKIDKQLGMICASIPTYKTTYGKVSLEELDLTVKDREISSHHHHHHGIKSMTYTFTGPIDRHLFYQFI
MKLPESVLRLKGYVSFRDQPNAIYEFQYAYGLPDYGIIGMQLPLTIVIIGETLDTNHIRNQLDMLQFT
>Mature_308_residues
MKNNKDEKIRISIINGFLGSGKTTLLTHYISELLKNDEKIKIIMNEFGTFDIDSNSISNEIEVHSLINGCVCCDLKQELV
YELKAIALKGDVNHVIIEATGIAHPLELLVACQDPQIVNFFEKPIIYGVLDATRFLERHQYTENTVSLMEDQLKLSDMII
INKIDLITDDSLEKIDKQLGMICASIPTYKTTYGKVSLEELDLTVKDREISSHHHHHHGIKSMTYTFTGPIDRHLFYQFI
MKLPESVLRLKGYVSFRDQPNAIYEFQYAYGLPDYGIIGMQLPLTIVIIGETLDTNHIRNQLDMLQFT

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=298, Percent_Identity=25.503355704698, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI126722884, Length=298, Percent_Identity=25.503355704698, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI223941779, Length=289, Percent_Identity=24.9134948096886, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI146231952, Length=292, Percent_Identity=25.6849315068493, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI148727351, Length=292, Percent_Identity=25.3424657534247, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI223941776, Length=281, Percent_Identity=24.5551601423488, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87082430, Length=284, Percent_Identity=26.056338028169, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788499, Length=226, Percent_Identity=27.8761061946903, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=223, Percent_Identity=28.2511210762332, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 35225; Mature: 35225

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNKDEKIRISIINGFLGSGKTTLLTHYISELLKNDEKIKIIMNEFGTFDIDSNSISNE
CCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEECCCCCCCCH
IEVHSLINGCVCCDLKQELVYELKAIALKGDVNHVIIEATGIAHPLELLVACQDPQIVNF
HHHHHHHCCCEEECCHHHHHHHHHHHEEECCCCEEEEEECCCCCHHHHEEECCCCHHHHH
FEKPIIYGVLDATRFLERHQYTENTVSLMEDQLKLSDMIIINKIDLITDDSLEKIDKQLG
HHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEEEEECCCCHHHHHHHHHH
MICASIPTYKTTYGKVSLEELDLTVKDREISSHHHHHHGIKSMTYTFTGPIDRHLFYQFI
HHHHCCCCCCCCCCEEEHHHCCEEEECCHHHHCCHHHCCCCEEEEEECCCHHHHHHHHHH
MKLPESVLRLKGYVSFRDQPNAIYEFQYAYGLPDYGIIGMQLPLTIVIIGETLDTNHIRN
HHHHHHHHHHHCEEEECCCCCEEEEEEEECCCCCCCEEEEECCEEEEEEECCCCHHHHHH
QLDMLQFT
HHHHHCCC
>Mature Secondary Structure
MKNNKDEKIRISIINGFLGSGKTTLLTHYISELLKNDEKIKIIMNEFGTFDIDSNSISNE
CCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEECCCCCCCCH
IEVHSLINGCVCCDLKQELVYELKAIALKGDVNHVIIEATGIAHPLELLVACQDPQIVNF
HHHHHHHCCCEEECCHHHHHHHHHHHEEECCCCEEEEEECCCCCHHHHEEECCCCHHHHH
FEKPIIYGVLDATRFLERHQYTENTVSLMEDQLKLSDMIIINKIDLITDDSLEKIDKQLG
HHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEEEEECCCCHHHHHHHHHH
MICASIPTYKTTYGKVSLEELDLTVKDREISSHHHHHHGIKSMTYTFTGPIDRHLFYQFI
HHHHCCCCCCCCCCEEEHHHCCEEEECCHHHHCCHHHCCCCEEEEEECCCHHHHHHHHHH
MKLPESVLRLKGYVSFRDQPNAIYEFQYAYGLPDYGIIGMQLPLTIVIIGETLDTNHIRN
HHHHHHHHHHHCEEEECCCCCEEEEEEEECCCCCCCEEEEECCEEEEEEECCCCHHHHHH
QLDMLQFT
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]