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The map label for this gene is ppaX [H]

Identifier: 57651448

GI number: 57651448

Start: 651644

End: 652300

Strand: Direct

Name: ppaX [H]

Synonym: SACOL0619

Alternate gene names: 57651448

Gene position: 651644-652300 (Clockwise)

Preceding gene: 57651447

Following gene: 57651449

Centisome position: 23.19

GC content: 34.7

Gene sequence:

>657_bases
GTGTTAATATTGAAGTTTGACAATTATATTTTTGATTTTGATGGTACGTTGGCAGACACGAAAAAATGTGGTGAAGTAGC
AACACAAAGTGCATTTAAAGCATGTGGCTTAACGGAACCATCATCTAAAGAAATAACGCATTATATGGGAATACCTATTG
AAGAATCATTTTTAAAATTAGCAGACCGACCATTAGATGAAGCAGCATTAGCAAAGTTAATCGATACATTTAGACATACA
TATCAATCTATTGAAAAGGACTATATTTATGAATTTGCGGGTATAACTGAAGCCATTACAAGTTTGTATAACCAAGGGAA
AAAACTTTTCGTGGTGTCTAGTAAGAAGAGTGATGTATTAGAAAGAAATTTATCGGCTATTGGATTAAATCACTTGATTA
CCGAAGCTGTTGGATCCGATCAAGTAAGTGCATATAAACCAAATCCTGAAGGCATACACACAATTGTGCAACGCTACAAT
TTAAATAGCCAACAAACGGTGTATATTGGTGATTCAACGTTTGATGTTGAGATGGCACAACGTGCTGGTATGCAATCTGC
AGCTGTCACTTGGGGTGCACATGATGCAAGGTCATTACTTCATTCAAATCCGGATTTTATTATTAATGATCCATCAGAAA
TTAATACCGTATTATAA

Upstream 100 bases:

>100_bases
AAAGATAGTCGATAATATGATGCCTAGGCAGAAATATTATCGATTATTTTTTTATTTAAATAATAAATTATAGTATAATA
TCAATAATAAACGAATAGGG

Downstream 100 bases:

>100_bases
AACTTGTTAAAACAGAGAATACCATGGTTAAAATGCATATTCATAAATATTAGATTATACTTAGAAATATTTCGCTTTAG
ATTAGGAATTTAAAATAAAT

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLILKFDNYIFDFDGTLADTKKCGEVATQSAFKACGLTEPSSKEITHYMGIPIEESFLKLADRPLDEAALAKLIDTFRHT
YQSIEKDYIYEFAGITEAITSLYNQGKKLFVVSSKKSDVLERNLSAIGLNHLITEAVGSDQVSAYKPNPEGIHTIVQRYN
LNSQQTVYIGDSTFDVEMAQRAGMQSAAVTWGAHDARSLLHSNPDFIINDPSEINTVL

Sequences:

>Translated_218_residues
MLILKFDNYIFDFDGTLADTKKCGEVATQSAFKACGLTEPSSKEITHYMGIPIEESFLKLADRPLDEAALAKLIDTFRHT
YQSIEKDYIYEFAGITEAITSLYNQGKKLFVVSSKKSDVLERNLSAIGLNHLITEAVGSDQVSAYKPNPEGIHTIVQRYN
LNSQQTVYIGDSTFDVEMAQRAGMQSAAVTWGAHDARSLLHSNPDFIINDPSEINTVL
>Mature_218_residues
MLILKFDNYIFDFDGTLADTKKCGEVATQSAFKACGLTEPSSKEITHYMGIPIEESFLKLADRPLDEAALAKLIDTFRHT
YQSIEKDYIYEFAGITEAITSLYNQGKKLFVVSSKKSDVLERNLSAIGLNHLITEAVGSDQVSAYKPNPEGIHTIVQRYN
LNSQQTVYIGDSTFDVEMAQRAGMQSAAVTWGAHDARSLLHSNPDFIINDPSEINTVL

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=223, Percent_Identity=23.7668161434978, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 24207; Mature: 24207

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILKFDNYIFDFDGTLADTKKCGEVATQSAFKACGLTEPSSKEITHYMGIPIEESFLKL
CEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHH
ADRPLDEAALAKLIDTFRHTYQSIEKDYIYEFAGITEAITSLYNQGKKLFVVSSKKSDVL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHH
ERNLSAIGLNHLITEAVGSDQVSAYKPNPEGIHTIVQRYNLNSQQTVYIGDSTFDVEMAQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHH
RAGMQSAAVTWGAHDARSLLHSNPDFIINDPSEINTVL
HCCCCHHHEECCCHHHHHHHHCCCCEEECCHHHHHCCC
>Mature Secondary Structure
MLILKFDNYIFDFDGTLADTKKCGEVATQSAFKACGLTEPSSKEITHYMGIPIEESFLKL
CEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHH
ADRPLDEAALAKLIDTFRHTYQSIEKDYIYEFAGITEAITSLYNQGKKLFVVSSKKSDVL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHH
ERNLSAIGLNHLITEAVGSDQVSAYKPNPEGIHTIVQRYNLNSQQTVYIGDSTFDVEMAQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHH
RAGMQSAAVTWGAHDARSLLHSNPDFIINDPSEINTVL
HCCCCHHHEECCCHHHHHHHHCCCCEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]