Click here to switch to the map view.

The map label for this gene is icaB

Identifier: 57651061

GI number: 57651061

Start: 2764824

End: 2765702

Strand: Direct

Name: icaB

Synonym: SACOL2691

Alternate gene names: 57651061

Gene position: 2764824-2765702 (Clockwise)

Preceding gene: 57651060

Following gene: 57651079

Centisome position: 98.41

GC content: 29.24

Gene sequence:

>879_bases
GTGAAGTATAGAAAATTTATAATTTTAGTGTTGAGTATCTTGATCATATTGCCTGTAAGCACACTGGATGGTCATCATAT
TGCAAATGCAGATGACGATTCACCTAAAAAACTGAAATATAAAGAAAATAGTGCTCTGGCATTAAATTATCACCGTGTAA
GAAAAGCGAATTTTCTGAATAATTTTATTTACTTCTTTTCTAGTAGTAAAGAAATTAAAAATTATAGTGTTAGTCAATCA
CAATTTGAATCTCAAATAAAATGGCTAAAATCACATGATGCTAAATTTTTAACCTTGAAAGAATTTTTATATTACAAGAA
AAAAGGTAAGTTTCCAAAACGAAGTGTATGGATTAACTTTGATGATATGGATGAAACTATTTATGAAAATGCTTATCCAA
TCTTAAAAAAATATAAAATACCGGCAACTGGGTTTATTATCACAGGTCATGTTGGGGAAGAAAACTTTCACAACCTCGAT
ATGATTAGTAAAAAAGAACTAAAAGAAATGTATAAAACTGGGTTATGGGAATTTGAAACACATACCCACGATTTGCATAA
CTTATCTAAAAATAATAAGTCAAAATTAATGAAAGCTTCTGAAGCTACAATCATAAAAGATTTAAACAAAAGTGAAAAAT
ATCTAACTAAAAACTTTAAAAAGTCGCAGAAAACTATAGCCTATCCTTATGGCTTGATGAATGACGATAAATTACCGGTA
ATCAAAAAAGCTGGGTTAAAATACGGTTTTTCATTAGAGGAAAAAGCAGTCACTCCGAACTCCAATGATTATTACATCCC
TAGAATATTAATTAGTGATGATGCTTTTGAGCATTTAATTAAGAGATGGGACGGATTCCATGAAAAAGATGAGACTTGA

Upstream 100 bases:

>100_bases
TTTTAGATATATTTGAAACTATGGGCATTTTCGCGATTATCATTTTTGTATTTTTTACAATTAGCATATTGATTCAAAAA
TGGCAGAGAGGAAGAGAATC

Downstream 100 bases:

>100_bases
ACTCGTATATTTACGTGCTATTATATGTGCAATTATTATTATCACACATTTACTTACACAAATTACTTTAAAACATGAAA
ATATGGAGGGTGGATCCTTA

Product: intercellular adhesion protein B

Products: NA

Alternate protein names: PNAG N-deacetylase; Poly-beta-1,6-GlcNAc N-deacetylase; Biofilm polysaccharide intercellular adhesin deacetylase; Biofilm PIA deacetylase; Intercellular adhesion protein B

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKYRKFIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQS
QFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLD
MISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKDET

Sequences:

>Translated_292_residues
MKYRKFIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQS
QFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLD
MISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKDET
>Mature_292_residues
MKYRKFIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQS
QFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLD
MISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKDET

Specific function: Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl- D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introd

COG id: COG0726

COG function: function code G; Predicted xylanase/chitin deacetylase

Gene ontology:

Cell location: Secreted, cell wall. Note=Attached to the cell surface

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide deacetylase family

Homologues:

Organism=Escherichia coli, GI1786322, Length=210, Percent_Identity=29.0476190476191, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ICAB_STAAC (Q5HCM9)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_187478.1
- ProteinModelPortal:   Q5HCM9
- STRING:   Q5HCM9
- EnsemblBacteria:   EBSTAT00000010302
- GeneID:   3238687
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL2691
- TIGR:   SACOL2691
- eggNOG:   COG0726
- GeneTree:   EBGT00050000024997
- HOGENOM:   HBG535609
- OMA:   WDELRIM
- ProtClustDB:   CLSK876769
- BioCyc:   SAUR93062:SACOL2691-MONOMER
- InterPro:   IPR011330
- InterPro:   IPR002509
- Gene3D:   G3DSA:3.20.20.370

Pfam domain/function: PF01522 Polysacc_deac_1; SSF88713 Glyco_hydro/deAcase_b/a-brl

EC number: NA

Molecular weight: Translated: 34336; Mature: 34336

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRKFIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLN
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHHHH
NFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINF
HHHEEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEEEE
DDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFET
CCHHHHHHHCCCHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEECC
HTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
CHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCH
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKDET
HHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKYRKFIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLN
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHHHH
NFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINF
HHHEEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEEEE
DDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFET
CCHHHHHHHCCCHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEECC
HTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
CHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCH
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKDET
HHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA