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The map label for this gene is icaD

Identifier: 57651060

GI number: 57651060

Start: 2764522

End: 2764827

Strand: Direct

Name: icaD

Synonym: SACOL2690

Alternate gene names: 57651060

Gene position: 2764522-2764827 (Clockwise)

Preceding gene: 57652406

Following gene: 57651061

Centisome position: 98.4

GC content: 31.37

Gene sequence:

>306_bases
ATGGTCAAGCCCAGACAGAGGGAATACCCAACGCTAAAATCATCGCTAAATATTGTAAGAGAAACAGCACTTATCGCTAT
ATCTTGTGTCTTTTGGATATATTGTTTAGTTGTTCTACTCGTTTATATTGGTACTATATTTGAAATTCATGACGAAAGTA
TCAATACAATACGTGTTGCTTTAAACATTGAAAATACTGAAATTTTAGATATATTTGAAACTATGGGCATTTTCGCGATT
ATCATTTTTGTATTTTTTACAATTAGCATATTGATTCAAAAATGGCAGAGAGGAAGAGAATCGTGA

Upstream 100 bases:

>100_bases
TTGTAAGTTGGTATCCGACAGTATACTGGATTATTAACGCAGCAGTAGTTCTTGTCGCATTTCCAAAAGCATTAAAACGT
AAGAAAGGTGGTTACGCAAC

Downstream 100 bases:

>100_bases
AGTATAGAAAATTTATAATTTTAGTGTTGAGTATCTTGATCATATTGCCTGTAAGCACACTGGATGGTCATCATATTGCA
AATGCAGATGACGATTCACC

Product: intercellular adhesion protein D

Products: NA

Alternate protein names: PGA synthesis protein IcaD; Poly-beta-1,6-GlcNAc synthesis protein IcaD; Biofilm polysaccharide intercellular adhesin synthesis protein IcaD; Biofilm PIA synthesis protein IcaD; Intercellular adhesion protein D

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAI
IIFVFFTISILIQKWQRGRES

Sequences:

>Translated_101_residues
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAI
IIFVFFTISILIQKWQRGRES
>Mature_101_residues
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAI
IIFVFFTISILIQKWQRGRES

Specific function: Necessary for the synthesis of poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Is required for full IcaA N- acetylglucosaminyltransferase activity

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IcaD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ICAD_STAA8 (Q9RQP8)

Other databases:

- EMBL:   AF086783
- EMBL:   CP000253
- PIR:   C90075
- RefSeq:   YP_501452.1
- STRING:   Q9RQP8
- EnsemblBacteria:   EBSTAT00000029299
- GeneID:   3921485
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_03003
- eggNOG:   NOG67708
- GeneTree:   EBGT00050000025402
- HOGENOM:   HBG693481
- OMA:   MESVITI
- ProtClustDB:   CLSK886142
- InterPro:   IPR020510
- ProDom:   PD068114

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 11783; Mature: 11783

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10d60e10)-; HASH(0xfe359f0)-;

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10496925