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The map label for this gene is sarT

Identifier: 57651005

GI number: 57651005

Start: 2563256

End: 2563612

Strand: Reverse

Name: sarT

Synonym: SACOL2506

Alternate gene names: 57651005

Gene position: 2563612-2563256 (Counterclockwise)

Preceding gene: 57651007

Following gene: 57651004

Centisome position: 91.25

GC content: 22.69

Gene sequence:

>357_bases
ATGAATGATTTGAAAAGCAAGAGCAATATTAAATTAATGAAAAGAGTATTAACTACATATGAGCTGCGTAAATATTTAAA
AAAATATTTTTGTCTTACATTAGATAATTATTTAGTATTAGCATATTTAGATGTATTTAAAAATGATGAAGGTAAATATT
TTATGAGAGACATTATAAGTTATATCGGTATAGACCAATCTAGAATTGTTAAAAGCGTAAAAGATTTATCAAAAAAGGGT
TACTTGAATAAATGTAGAGACCCACATGATAGTAGAAATGTAATCATTGTTGTTTCTGTAAAACAACACAATTATATTAA
AAATCTTTTGAGTGAAATAAATATTAATGAAACATAA

Upstream 100 bases:

>100_bases
GTTTATAGCTAGCACCACAAACTAAATATATTTGGAGTTATTACTAGTTAAAGACAAATATTATTTGACGTGACAATTAA
AAGTAAGGGATGAAGACTTG

Downstream 100 bases:

>100_bases
AGTATGTTTCGAGATTTTAATATCTTGGTGCAGTTAAATGTATTTTTAAATGCGTTAAGGTATTTTTTATTTTAGAAATT
CAATGCTATTGAGTTGATGG

Product: accessory regulator T

Products: NA

Alternate protein names: Staphylococcal accessory regulator T

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKDLSKKG
YLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET

Sequences:

>Translated_118_residues
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKDLSKKG
YLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
>Mature_118_residues
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKDLSKKG
YLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET

Specific function: Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha-hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sarA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SART_STAA8 (Q2G2B1)

Other databases:

- EMBL:   CP000253
- RefSeq:   YP_501258.1
- ProteinModelPortal:   Q2G2B1
- SMR:   Q2G2B1
- STRING:   Q2G2B1
- EnsemblBacteria:   EBSTAT00000030049
- GeneID:   3921453
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_02799
- eggNOG:   COG1846
- GeneTree:   EBGT00050000023834
- HOGENOM:   HBG693006
- ProtClustDB:   CLSK886022
- BioCyc:   SAUR93061:SAOUHSC_02799-MONOMER
- GO:   GO:0005737
- GO:   GO:0009405
- GO:   GO:0006350
- InterPro:   IPR010166
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR01889

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 13989; Mature: 13989

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
YIGIDQSRIVKSVKDLSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
HHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
YIGIDQSRIVKSVKDLSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
HHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12496184