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The map label for this gene is galU

Identifier: 57651007

GI number: 57651007

Start: 2564890

End: 2565756

Strand: Reverse

Name: galU

Synonym: SACOL2508

Alternate gene names: 57651007

Gene position: 2565756-2564890 (Counterclockwise)

Preceding gene: 57651008

Following gene: 57651005

Centisome position: 91.33

GC content: 36.56

Gene sequence:

>867_bases
TTGAAAAAAATAAAAAAGGCAATCATTCCCGCTGCTGGTTTAGGGACTAGATTTTTACCAGCAACTAAAGCGATGCCAAA
GGAAATGCTTCCTATCTTAGATAAACCCACAATACAATATATCGTTGAAGAAGCTGCAAGAGCTGGAATTGAAGATATTA
TTATAGTGACAGGTCGCCACAAACGCGCGATTGAAGATCATTTTGATAGTCAAAAAGAATTAGAAATGGTGTTAAAAGAA
AAAGGTAAATCTGAATTACTAGAGAAAGTTCAGTATTCAACGGAACTTGCGAATATTTTTTATGTAAGGCAGAAAGAACA
AAAAGGTTTAGGGCATGCGATTAGTTCTGCGCGTCAATTTATCGGCAATGAACCATTTGCGGTATTATTAGGTGACGATA
TTGTTGAATCTGAAGTGCCAGCAGTGAAACAGTTGATTGACGTTTATGAAGAAACAGGGCACTCAGTTATAGGTGTCCAA
GAAGTTCCGGAAGCAGATACTCATCGTTATGGAATTATTGACCCATTAACTAAAAACGGACGTCAGTATGAAGTGAAAAA
GTTTGTTGAAAAGCCAGCACAAGGTACGGCACCATCAAACCTAGCTATTATGGGACGTTATGTATTAACGCCTGAAATTT
TCGATTATTTAAAAACGCAAAAAGAAGGCGCAGGTAACGAAATTCAGTTAACAGATGCGATTGAACGTATGAATAATGAT
AACCAAGTGTATGCATATGACTTCGAAGGCGAACGTTATGACGTTGGAGAAAAATTAGGCTTCGTTAAAACTACCATAGA
ATATGCATTGAAAGATGACAGTATGCGAGAAGAATTAACACGATTTATTAAAGCATTAGGTTTATAA

Upstream 100 bases:

>100_bases
AAATAATTACATACTCAATGACACTATGAAGGCGTTCTAATTAGTGTTAAAATGACGTTGATACATAGATTTAATACTTA
GGAAAAGGAGCACATTAACT

Downstream 100 bases:

>100_bases
CATTAAAAGCATGATACTCAGTAAAATTGGAACACGAAATGGTGAACTAAATTGAATGAGTGTCATGCTTAATTTATGTG
TTGTGATATATAGTAGGGTA

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKE
KGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQ
EVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNND
NQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKALGL

Sequences:

>Translated_288_residues
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKE
KGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQ
EVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNND
NQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKALGL
>Mature_288_residues
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKE
KGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQ
EVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNND
NQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKALGL

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a mem

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family

Homologues:

Organism=Homo sapiens, GI11761621, Length=259, Percent_Identity=24.7104247104247, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI11761619, Length=259, Percent_Identity=24.7104247104247, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787488, Length=291, Percent_Identity=44.6735395189003, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788355, Length=277, Percent_Identity=42.2382671480144, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1788351, Length=231, Percent_Identity=29.8701298701299, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790224, Length=244, Percent_Identity=28.2786885245902, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): GTAB_STAA3 (Q2FE05)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_495073.1
- ProteinModelPortal:   Q2FE05
- SMR:   Q2FE05
- STRING:   Q2FE05
- EnsemblBacteria:   EBSTAT00000037801
- GeneID:   3914648
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_2439
- eggNOG:   COG1210
- GeneTree:   EBGT00050000024505
- HOGENOM:   HBG688195
- ProtClustDB:   CLSK748218
- InterPro:   IPR005771
- InterPro:   IPR005835
- TIGRFAMs:   TIGR01099

Pfam domain/function: PF00483 NTP_transferase

EC number: =2.7.7.9

Molecular weight: Translated: 32452; Mature: 32452

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRH
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQF
HHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQEVPEADTHRYGIIDPLTKNG
HCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCCCCCCCCHHCCC
RQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNND
CCHHHHHHHHCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHCCCC
NQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKALGL
CEEEEEECCCCEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRH
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQF
HHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQEVPEADTHRYGIIDPLTKNG
HCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCCCCCCCCHHCCC
RQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNND
CCHHHHHHHHCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHCCCC
NQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKALGL
CEEEEEECCCCEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA