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The map label for this gene is bioD [H]

Identifier: 57650972

GI number: 57650972

Start: 2486658

End: 2487344

Strand: Reverse

Name: bioD [H]

Synonym: SACOL2428

Alternate gene names: 57650972

Gene position: 2487344-2486658 (Counterclockwise)

Preceding gene: 57650973

Following gene: 57650971

Centisome position: 88.54

GC content: 32.02

Gene sequence:

>687_bases
ATGAGGATTTTTATTACAAGTACGAATACTGATGTAGGCAAAACCTATGTTACAAAGCATTTATACCATGCTTTGAAAAC
ACGTGGTCATCGAGTTTGTATTTTTAAACCATTTCAAACTGAGGAACGCCAAGACGGGACGTTTCCAGATTTAGAAGTAT
TTAAAAATGAATGTGATTTAAGCTATGACATAACGTCACTTTATACTTTTAAGCAACCTGTATCACCACACCTTGCATTT
AAAATGACAGATCAAATTTTTCTAAATAAGCAGCGTGTATTAGATAAGGTAAAAGTTTTAGATAAGGAATTTGATTTTAT
CTTAATTGAGGGTGCTGGGGGAATTGCCGTACCAATATATGAAGGTACAGATGATTTCTACATGACTAAAGATCTAATCA
ATGATTGTGCAGATTGTGTCATCAGTGTGTTGCCATCAAAATTAGGTGCTATTAGCGATGCCATTGTTCACCAAGATTAT
GTTAATCAGAATGTATCGGCGAGTAATTTTTTAATAATGAATCGCTATACAGACAGCTATATTGAAAAAGACAATCAAAT
GACGATTGGAAAATTAACAAATAAAACAGTCTATACATTTGAAGAACATGCCACGTATGAAAATTTCTCAGAAGCATTTT
TAAAACAATTAATAGGAGTTAAAAATGAATTACACACAACAACTTAA

Upstream 100 bases:

>100_bases
TACTGAGAAGTTTAAATTCATGTTTTCTTGAAAAACATGCGCCTTAAATGTAAACTTATTAATTATAAAAGTTTACATTT
GGATTGAGGTGGTTATTTTT

Downstream 100 bases:

>100_bases
ACAAAAAGACTCAGAATATGTTTGGCATCCATTTACACAAATGGGTGTATATAGCAAAGAAGAAGCAATCATCATTGAAA
AAGGAAAGGGTAGTTACCTT

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAF
KMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDY
VNQNVSASNFLIMNRYTDSYIEKDNQMTIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT

Sequences:

>Translated_228_residues
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAF
KMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDY
VNQNVSASNFLIMNRYTDSYIEKDNQMTIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
>Mature_228_residues
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAF
KMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDY
VNQNVSASNFLIMNRYTDSYIEKDNQMTIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=166, Percent_Identity=30.1204819277108, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26159; Mature: 26159

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDL
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCC
SYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIY
EECHHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEE
EGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSY
ECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHH
IEKDNQMTIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
HCCCCCEEEEECCCCEEEEEHHHCCHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDL
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCC
SYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIY
EECHHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEE
EGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSY
ECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHH
IEKDNQMTIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
HCCCCCEEEEECCCCEEEEEHHHCCHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA