Click here to switch to the map view.

The map label for this gene is mqo1

Identifier: 57650909

GI number: 57650909

Start: 2420487

End: 2421965

Strand: Reverse

Name: mqo1

Synonym: SACOL2362

Alternate gene names: 57650909

Gene position: 2421965-2420487 (Counterclockwise)

Preceding gene: 57650910

Following gene: 57650904

Centisome position: 86.21

GC content: 35.7

Gene sequence:

>1479_bases
ATGACAACACAACATAGCAAAACAGATGTCATCTTAATTGGTGGCGGTATTATGAGTGCAACATTAGGAACATTACTTAA
AGAATTATCACCTGAGAAAAATATTAAAGTGTTTGAAAAATTAGCACAACCTGGCGAAGAGAGTTCAAATGTATGGAATA
ATGCCGGTACAGGGCATTCAGCACTTTGCGAGTTGAACTATACAAAAGAAGGTAAGGATGGCACAGTTGATTGTAGTAAA
GCAATTAAGATAAATGAGCAGTACCAAATTTCAAAACAGTTTTGGGCATATTTAGTTAAAACAGGACAATTAGATAACCC
AGATCGCTTTATTCAAGCGGTGCCACACATGAGTTTTGTCATTGGCGAAGATAATGTAGCTTTTATAAAAAGTCGTGTTG
CAACGTTAAAGAAAAGTATTTTATTCGAAAAAATGAAATTATCGCAAGATGAAGAAGAAATGAAATCTTGGGTACCGTTA
ATGATTGAAGGTCGTAAGTCTGATGAACCAATTGCTTTAACTTATGATGAAACTGGTACAGATGTTAACTTTGGTGCGTT
AACTGCAAAGTTATTTGATAATTTAGAGCAACGTGGTGTGGGAATTCAATATAAGCAGAATGTATTAGACATCAAGAAAC
AGAAATCTGGGGTATGGCTAGTTAAAGTTAAAGATTTAGAAACTAATGAAACGACAACATATGAATCTGATTTTGTATTT
ATTGGTGCTGGCGGTGCGAGTTTACCATTACTCCAAAAGACTGGGATTAAACAATCAAAACATATTGGTGGTTTCCCGGT
AAGTGGATTATTCCTGCGCTGTACAAATCAAGAAGTGATTGATCGTCATCATGCTAAAGTGTACGGAAAAGCAGCAGTGG
GTGCGCCACCAATGTCAGTGCCGCACTTAGATACACGTTTTGTAGACGGCAAGCGTTCATTGTTATTTGGTCCATTTGCA
GGTTTCTCACCTAAATTTTTAAAAACAGGTTCACATATGGATTTAATTAAATCGGTTAAACCAAATAATATCGTGACGAT
GTTATCTGCAGGTATCAAAGAAATGAGTCTTACGAAGTATTTAGTGTCACAATTGATGTTATCTAATGATGAGCGTATGG
ATGATTTAAGAGTCTTTTTCCCAAATGCTAAAAATGAAGATTGGGAAGTGATTACAGCAGGGCAACGTGTCCAAGTAATC
AAGGATACTGAGGATTCTAAAGGTAACTTACAATTTGGTACTGAAGTTATTACGTCAGATGATGGCACATTAGCTGCATT
ACTTGGTGCATCACCTGGTGCGTCAACAGCTGTAGATATTATGTTTGATGTTTTACAGAGATGCTATCGTGATGAATTCA
AAGGATGGGAACCAAAGATTAAAGAAATGGTGCCGTCATTTGGTTATCGCTTAACAGATCATGAGGATTTATATCATAAA
ATTAATGAAGAAGTAACTAAGTATTTACAAGTTAAATAA

Upstream 100 bases:

>100_bases
TGGGAACCTATTGAGACACTTATTGATTTAAAGTGGTATTAATATGTCGTATTTCTCGAACGTTCCATTATTCATTTTAA
AAAGGGGGACTGTATTTGTT

Downstream 100 bases:

>100_bases
TAAACGAAACGGTAATGTCTTTTTTAATGTGATAGACATTACCGTTTTTTAGTGGTTAATAAAAATCATTTTAATTGTTT
CAGTTGCTTGTTAATAGTGT

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO 1; Malate dehydrogenase [quinone] 1

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MTTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQPGEESSNVWNNAGTGHSALCELNYTKEGKDGTVDCSK
AIKINEQYQISKQFWAYLVKTGQLDNPDRFIQAVPHMSFVIGEDNVAFIKSRVATLKKSILFEKMKLSQDEEEMKSWVPL
MIEGRKSDEPIALTYDETGTDVNFGALTAKLFDNLEQRGVGIQYKQNVLDIKKQKSGVWLVKVKDLETNETTTYESDFVF
IGAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTNQEVIDRHHAKVYGKAAVGAPPMSVPHLDTRFVDGKRSLLFGPFA
GFSPKFLKTGSHMDLIKSVKPNNIVTMLSAGIKEMSLTKYLVSQLMLSNDERMDDLRVFFPNAKNEDWEVITAGQRVQVI
KDTEDSKGNLQFGTEVITSDDGTLAALLGASPGASTAVDIMFDVLQRCYRDEFKGWEPKIKEMVPSFGYRLTDHEDLYHK
INEEVTKYLQVK

Sequences:

>Translated_492_residues
MTTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQPGEESSNVWNNAGTGHSALCELNYTKEGKDGTVDCSK
AIKINEQYQISKQFWAYLVKTGQLDNPDRFIQAVPHMSFVIGEDNVAFIKSRVATLKKSILFEKMKLSQDEEEMKSWVPL
MIEGRKSDEPIALTYDETGTDVNFGALTAKLFDNLEQRGVGIQYKQNVLDIKKQKSGVWLVKVKDLETNETTTYESDFVF
IGAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTNQEVIDRHHAKVYGKAAVGAPPMSVPHLDTRFVDGKRSLLFGPFA
GFSPKFLKTGSHMDLIKSVKPNNIVTMLSAGIKEMSLTKYLVSQLMLSNDERMDDLRVFFPNAKNEDWEVITAGQRVQVI
KDTEDSKGNLQFGTEVITSDDGTLAALLGASPGASTAVDIMFDVLQRCYRDEFKGWEPKIKEMVPSFGYRLTDHEDLYHK
INEEVTKYLQVK
>Mature_491_residues
TTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQPGEESSNVWNNAGTGHSALCELNYTKEGKDGTVDCSKA
IKINEQYQISKQFWAYLVKTGQLDNPDRFIQAVPHMSFVIGEDNVAFIKSRVATLKKSILFEKMKLSQDEEEMKSWVPLM
IEGRKSDEPIALTYDETGTDVNFGALTAKLFDNLEQRGVGIQYKQNVLDIKKQKSGVWLVKVKDLETNETTTYESDFVFI
GAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTNQEVIDRHHAKVYGKAAVGAPPMSVPHLDTRFVDGKRSLLFGPFAG
FSPKFLKTGSHMDLIKSVKPNNIVTMLSAGIKEMSLTKYLVSQLMLSNDERMDDLRVFFPNAKNEDWEVITAGQRVQVIK
DTEDSKGNLQFGTEVITSDDGTLAALLGASPGASTAVDIMFDVLQRCYRDEFKGWEPKIKEMVPSFGYRLTDHEDLYHKI
NEEVTKYLQVK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=473, Percent_Identity=50.7399577167019, Blast_Score=502, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO1_STAAC (Q5HDJ0)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_187167.1
- ProteinModelPortal:   Q5HDJ0
- STRING:   Q5HDJ0
- EnsemblBacteria:   EBSTAT00000010490
- GeneID:   3236601
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL2362
- TIGR:   SACOL2362
- eggNOG:   COG0579
- GeneTree:   EBGT00050000024300
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- ProtClustDB:   PRK05257
- BioCyc:   SAUR93062:SACOL2362-MONOMER
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 54814; Mature: 54683

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQPGEESSNVWNNAGTGHS
CCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
ALCELNYTKEGKDGTVDCSKAIKINEQYQISKQFWAYLVKTGQLDNPDRFIQAVPHMSFV
EEEEEECCCCCCCCCEECCHHEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEE
IGEDNVAFIKSRVATLKKSILFEKMKLSQDEEEMKSWVPLMIEGRKSDEPIALTYDETGT
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCCCEEEEECCCCC
DVNFGALTAKLFDNLEQRGVGIQYKQNVLDIKKQKSGVWLVKVKDLETNETTTYESDFVF
CCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEEEECCCCCCEEECCCEEE
IGAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTNQEVIDRHHAKVYGKAAVGAPPMSV
EECCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHEECCCCCCCCCCC
PHLDTRFVDGKRSLLFGPFAGFSPKFLKTGSHMDLIKSVKPNNIVTMLSAGIKEMSLTKY
CCCCCEECCCCCCEEEECCCCCCHHHHCCCCHHHHHHHCCCCCCHHHHHHCHHHHHHHHH
LVSQLMLSNDERMDDLRVFFPNAKNEDWEVITAGQRVQVIKDTEDSKGNLQFGTEVITSD
HHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECCCEEEEEECCCCCCCCEEECCEEEECC
DGTLAALLGASPGASTAVDIMFDVLQRCYRDEFKGWEPKIKEMVPSFGYRLTDHEDLYHK
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
INEEVTKYLQVK
HHHHHHHHHCCC
>Mature Secondary Structure 
TTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQPGEESSNVWNNAGTGHS
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
ALCELNYTKEGKDGTVDCSKAIKINEQYQISKQFWAYLVKTGQLDNPDRFIQAVPHMSFV
EEEEEECCCCCCCCCEECCHHEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEE
IGEDNVAFIKSRVATLKKSILFEKMKLSQDEEEMKSWVPLMIEGRKSDEPIALTYDETGT
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCCCEEEEECCCCC
DVNFGALTAKLFDNLEQRGVGIQYKQNVLDIKKQKSGVWLVKVKDLETNETTTYESDFVF
CCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEEEECCCCCCEEECCCEEE
IGAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTNQEVIDRHHAKVYGKAAVGAPPMSV
EECCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHEECCCCCCCCCCC
PHLDTRFVDGKRSLLFGPFAGFSPKFLKTGSHMDLIKSVKPNNIVTMLSAGIKEMSLTKY
CCCCCEECCCCCCEEEECCCCCCHHHHCCCCHHHHHHHCCCCCCHHHHHHCHHHHHHHHH
LVSQLMLSNDERMDDLRVFFPNAKNEDWEVITAGQRVQVIKDTEDSKGNLQFGTEVITSD
HHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECCCEEEEEECCCCCCCCEEECCEEEECC
DGTLAALLGASPGASTAVDIMFDVLQRCYRDEFKGWEPKIKEMVPSFGYRLTDHEDLYHK
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
INEEVTKYLQVK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA