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The map label for this gene is lctP [H]

Identifier: 57650910

GI number: 57650910

Start: 2422346

End: 2423944

Strand: Reverse

Name: lctP [H]

Synonym: SACOL2363

Alternate gene names: 57650910

Gene position: 2423944-2422346 (Counterclockwise)

Preceding gene: 57650912

Following gene: 57650909

Centisome position: 86.28

GC content: 32.27

Gene sequence:

>1599_bases
ATGTTAGTAAATACGTTTAACCCATTTGATAATTTATTATTATCGTCTTTAATTGCAGCAATACCGATTGTACTGTTTTT
ACTATGTTTAACTGTTTTTAAAATGAAAGGTATTTATGCAGCTATTACAACACTTGTTGTAACATTACTAATTGCAATAC
CATTTTTCAAATTGCCAGTTGGTATCGCTTCTGGTGCAGTAGTCGAAGGTTTCTTCCAAGGTATCATTCCGATTGGCTAT
ATCGTTATGATGGCAGTATTGTTATACAAAATTACTGTTGAATCTGGACAATTTTTAACAATTCAAGATAGTATTACAAA
TATTTCACAAGACCAACGTATTCAAGTTTTACTTATTGGATTTGCATTCAACGCATTTTTAGAAGGTGCAGCAGGATTTG
GTGTACCAATTGCAATTTGTGCACTTTTATTAACACAATTAGGATTTAATCCATTAAAAGCTGCGATGTTATGTTTAGTC
GCAAATGCAGCGTCTGGTGCTTTTGGTGCGATTGGTATCCCTGTAGGTGTTGTAGAAACGTTGAAATTACCTGGAGATGT
TTCAGTATTAGGTGTTTCTCAATCAGCAACTTTAACATTGGCAATCATAAATTTCATTATTCCATTCTTACTTATCTTTA
TTATTGATGGTTTTAGAGGTGTTAAAGAAACATTACCAGCAATTTTAGTAGTTTCAATCACTTATACACTTACTCAAGGA
TTATTAACTGTATTCAGTGGACCTGAATTAGCAGATATTATTCCACCGTTATTAACAATGTTAGCATTAGCAGTATTTTC
TAAAAAATTCCAACCAAAACACATTTATCGTGTTAATAAAGATGAAGAAATTGAACCTGCAAAAGCACATTCTGCAAAAG
CAGTATTACATGCATGGAGCCCATTCATTGTATTAACAGTCATTGTAATGATTTGGAGTGCGCCATTCTTTAAAAACTTA
TTCTTACCAAATGGTGCTTTATCATCATTAGTATTTAAATTCAACTTACCTGGAACAATCAGCGAAGTTACGCATAAACC
ATTAGTATTGACTTTAAATATTATTGGACAAACAGGTACAGCTATTTTATTAACTATTATTATTACAATTTTAATGTCTA
AAAAGGTTAACTTTAAAGATGCAGGTAGATTATTCGGCGTTACATTTAAAGAGTTGTGGTTACCAGTTCTTACAATTTGT
TTCATCTTAGCAATTTCTAAAATCACAACTTATGGTGGTTTAAGTGCAGCAATGGGTCAAGGTATTGCTAAAGCAGGTAA
TGTCTTCCCAGTTCTATCACCAATTTTAGGTTGGATAGGTGTGTTTATGACAGGATCAGTTGTAAATAACAACTCATTAT
TTGCACCAATTCAAGCTTCTGTTGCACAACAAATTGGAACAAGTGGTTCACTTCTTGTATCTGCTAATACAGTTGGTGGT
GTAGCGGCAAAATTGATTTCACCACAATCAATTGCAATTGCAACTGCAGCAGTAAAACAAGTTGGTAAGGAATCAGAATT
ATTAAAAATGACATTGAAATACAGTGTATGTTTACTAATATTCATCTGTATTTGGACTTTCATCTTGTCATTATTATAA

Upstream 100 bases:

>100_bases
CACTGTTCTGTAAAATGTTATCGATAACAAAATGCTATAGCCAGAGCATGATTTTAATGAAGCAATTACACTACTACTTT
ATGGAAAGAAGAGTCAGCCT

Downstream 100 bases:

>100_bases
AAAAACGTATTTCAAAATATAAATATACAGAAGGTGAGATGTTTTCTAACATCTCATCTTTTTTTTATGGATCATTAATG
AAAGAAGTTTGACATTATAA

Product: L-lactate permease

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGY
IVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLV
ANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTLTQG
LLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNL
FLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAGRLFGVTFKELWLPVLTIC
FILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGG
VAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL

Sequences:

>Translated_532_residues
MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGY
IVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLV
ANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTLTQG
LLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNL
FLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAGRLFGVTFKELWLPVLTIC
FILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGG
VAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL
>Mature_532_residues
MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGY
IVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLV
ANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTLTQG
LLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNL
FLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAGRLFGVTFKELWLPVLTIC
FILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGG
VAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=536, Percent_Identity=44.7761194029851, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1789347, Length=534, Percent_Identity=41.9475655430712, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 56643; Mature: 56643

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIASGAVVEGFFQGIIPIGYIVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEHHHHCCCCCCCEEEEEEH
FAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLVANAASGAFGAIGIPVGVVET
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
LKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTLTQG
HCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCC
PFIVLTVIVMIWSAPFFKNLFLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGT
HHHHHHHHHHHHCCHHHHHHCCCCCHHHHEEEEECCCCCHHHHCCCCEEEEEEECCCCHH
AILLTIIITILMSKKVNFKDAGRLFGVTFKELWLPVLTICFILAISKITTYGGLSAAMGQ
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
GIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGG
CHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCEECHHHHHHHHHHCCCCCEEEEECCHHH
VAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIASGAVVEGFFQGIIPIGYIVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEHHHHCCCCCCCEEEEEEH
FAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLVANAASGAFGAIGIPVGVVET
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
LKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTLTQG
HCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCC
PFIVLTVIVMIWSAPFFKNLFLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGT
HHHHHHHHHHHHCCHHHHHHCCCCCHHHHEEEEECCCCCHHHHCCCCEEEEEEECCCCHH
AILLTIIITILMSKKVNFKDAGRLFGVTFKELWLPVLTICFILAISKITTYGGLSAAMGQ
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
GIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGG
CHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCEECHHHHHHHHHHCCCCCEEEEECCHHH
VAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]