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The map label for this gene is ftsW [H]

Identifier: 57650757

GI number: 57650757

Start: 2142241

End: 2143443

Strand: Direct

Name: ftsW [H]

Synonym: SACOL2075

Alternate gene names: 57650757

Gene position: 2142241-2143443 (Clockwise)

Preceding gene: 57650753

Following gene: 57650761

Centisome position: 76.25

GC content: 33.0

Gene sequence:

>1203_bases
ATGAATTATTCATCTCGTCAACAGCCGGATAAGCATTGGCTTCGCAAAGTAGACTGGGTATTAGTAGCCACTATAGCTGT
TTTAGCAATTTTCAGTGTTCTGCTTATTAACTCGGCAATGGGCGGTGGTCAATACAGTGCTAATTTCGGTATCAGACAAA
TTTTTTATTACATTTTAGGTGCAATTTTTGCAGGTATCATCATGTTTATTTCACCTAAAAAGATTAAACATTATACATAT
TTATTGTATTTCTTAATCTGTCTATTATTAATAGGCTTGCTCGTTATTCCTGAGTCACCTATTACACCTATTATCAATGG
TGCCAAAAGTTGGTACACGTTTGGCCCTATCAGTATTCAGCCATCTGAATTCATGAAAATTATTTTAATTTTAGCATTAG
CGCGTGTCGTTTCTAGACATAATCAATTCACATTCAATAAATCATTCCAAAGTGATTTGTTATTATTTTTCAAAATTATT
GGTGTCTCGTTAGTACCAAGTATTTTAATATTACTGCAAAATGACCTAGGAACTACATTAGTATTAGCTGCTATTATTGC
AGGTGTGATGTTAGTAAGTGGTATAACATGGCGTATCTTAGCACCTATCTTTATTACAGGTATTGTTGGTGCAATGACAG
TCATTTTAGGTATTCTATATGCACCCGCATTAATTGAAAATTTATTAGGTGTCCAACTGTATCAAATGGGACGAATCAAT
TCATGGCTTGACCCCTATACATATAGTAGTGGTGATGGCTATCATTTAACTGAATCACTTAAAGCTATCGGTTCTGGACA
GTTACTAGGTAAAGGATACAATCACGGTGAAGTTTATATACCTGAAAATCATACTGACTTTATCTTTTCAGTGATTGGAG
AGGAACTTGGCTTTATCGGTTCTGTCATATTGATCTTAATATTTTTATTTTTAATCTTCCATCTAATAAGATTAGCTGCG
AAAATTGAAGATCAATTTAACAAAATCTTTATCGTTGGTTTCGTCACTTTACTTGTGTTCCATATTTTACAAAATATTGG
TATGACAATTCAGTTGTTACCAATCACTGGTATTCCATTACCATTTATTAGTTATGGTGGTAGTGCGCTATGGAGTATGA
TGACTGGAATAGGTATAGTCTTATCAATTTATTATCATGAACCAAAACGATATGTCGATTTATACCATCCAAAAAGTAAT
TAA

Upstream 100 bases:

>100_bases
AATTGAAATCTATAGCTGATATCACTGTGATATTCTAGCTAATTTTTAAAAAGTCATGTAAAATTGATATAAACATTAGT
GAGTATAAAAGGAGTTTGCA

Downstream 100 bases:

>100_bases
TTTAAACTATTTTGAGTTTCAAATATCATAACTTTTCAAGATGACGTTATATAGTCTATTTACGTCGTCGATTTAAAATG
TCATATATAGATATTACTCG

Product: cell cycle protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MNYSSRQQPDKHWLRKVDWVLVATIAVLAIFSVLLINSAMGGGQYSANFGIRQIFYYILGAIFAGIIMFISPKKIKHYTY
LLYFLICLLLIGLLVIPESPITPIINGAKSWYTFGPISIQPSEFMKIILILALARVVSRHNQFTFNKSFQSDLLLFFKII
GVSLVPSILILLQNDLGTTLVLAAIIAGVMLVSGITWRILAPIFITGIVGAMTVILGILYAPALIENLLGVQLYQMGRIN
SWLDPYTYSSGDGYHLTESLKAIGSGQLLGKGYNHGEVYIPENHTDFIFSVIGEELGFIGSVILILIFLFLIFHLIRLAA
KIEDQFNKIFIVGFVTLLVFHILQNIGMTIQLLPITGIPLPFISYGGSALWSMMTGIGIVLSIYYHEPKRYVDLYHPKSN

Sequences:

>Translated_400_residues
MNYSSRQQPDKHWLRKVDWVLVATIAVLAIFSVLLINSAMGGGQYSANFGIRQIFYYILGAIFAGIIMFISPKKIKHYTY
LLYFLICLLLIGLLVIPESPITPIINGAKSWYTFGPISIQPSEFMKIILILALARVVSRHNQFTFNKSFQSDLLLFFKII
GVSLVPSILILLQNDLGTTLVLAAIIAGVMLVSGITWRILAPIFITGIVGAMTVILGILYAPALIENLLGVQLYQMGRIN
SWLDPYTYSSGDGYHLTESLKAIGSGQLLGKGYNHGEVYIPENHTDFIFSVIGEELGFIGSVILILIFLFLIFHLIRLAA
KIEDQFNKIFIVGFVTLLVFHILQNIGMTIQLLPITGIPLPFISYGGSALWSMMTGIGIVLSIYYHEPKRYVDLYHPKSN
>Mature_400_residues
MNYSSRQQPDKHWLRKVDWVLVATIAVLAIFSVLLINSAMGGGQYSANFGIRQIFYYILGAIFAGIIMFISPKKIKHYTY
LLYFLICLLLIGLLVIPESPITPIINGAKSWYTFGPISIQPSEFMKIILILALARVVSRHNQFTFNKSFQSDLLLFFKII
GVSLVPSILILLQNDLGTTLVLAAIIAGVMLVSGITWRILAPIFITGIVGAMTVILGILYAPALIENLLGVQLYQMGRIN
SWLDPYTYSSGDGYHLTESLKAIGSGQLLGKGYNHGEVYIPENHTDFIFSVIGEELGFIGSVILILIFLFLIFHLIRLAA
KIEDQFNKIFIVGFVTLLVFHILQNIGMTIQLLPITGIPLPFISYGGSALWSMMTGIGIVLSIYYHEPKRYVDLYHPKSN

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=364, Percent_Identity=33.7912087912088, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786277, Length=374, Percent_Identity=32.620320855615, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44602; Mature: 44602

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSSRQQPDKHWLRKVDWVLVATIAVLAIFSVLLINSAMGGGQYSANFGIRQIFYYILG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AIFAGIIMFISPKKIKHYTYLLYFLICLLLIGLLVIPESPITPIINGAKSWYTFGPISIQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEECCCCCCC
PSEFMKIILILALARVVSRHNQFTFNKSFQSDLLLFFKIIGVSLVPSILILLQNDLGTTL
HHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VLAAIIAGVMLVSGITWRILAPIFITGIVGAMTVILGILYAPALIENLLGVQLYQMGRIN
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SWLDPYTYSSGDGYHLTESLKAIGSGQLLGKGYNHGEVYIPENHTDFIFSVIGEELGFIG
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
SVILILIFLFLIFHLIRLAAKIEDQFNKIFIVGFVTLLVFHILQNIGMTIQLLPITGIPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCH
PFISYGGSALWSMMTGIGIVLSIYYHEPKRYVDLYHPKSN
HHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCC
>Mature Secondary Structure
MNYSSRQQPDKHWLRKVDWVLVATIAVLAIFSVLLINSAMGGGQYSANFGIRQIFYYILG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AIFAGIIMFISPKKIKHYTYLLYFLICLLLIGLLVIPESPITPIINGAKSWYTFGPISIQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEECCCCCCC
PSEFMKIILILALARVVSRHNQFTFNKSFQSDLLLFFKIIGVSLVPSILILLQNDLGTTL
HHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VLAAIIAGVMLVSGITWRILAPIFITGIVGAMTVILGILYAPALIENLLGVQLYQMGRIN
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SWLDPYTYSSGDGYHLTESLKAIGSGQLLGKGYNHGEVYIPENHTDFIFSVIGEELGFIG
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
SVILILIFLFLIFHLIRLAAKIEDQFNKIFIVGFVTLLVFHILQNIGMTIQLLPITGIPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCH
PFISYGGSALWSMMTGIGIVLSIYYHEPKRYVDLYHPKSN
HHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]