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The map label for this gene is splB [H]

Identifier: 57650603

GI number: 57650603

Start: 1919938

End: 1920660

Strand: Reverse

Name: splB [H]

Synonym: SACOL1868

Alternate gene names: 57650603

Gene position: 1920660-1919938 (Counterclockwise)

Preceding gene: 57650604

Following gene: 57650602

Centisome position: 68.36

GC content: 33.33

Gene sequence:

>723_bases
ATGAACAAAAACGTAGTCATCAAGAGTTTAGCAGCATTAACAATTTTAACATCTGTAACAGGTATTGGAACAACATTGGT
TGAGGAAGTACAACAAACTGCCAAAGCAGAAAATAATGTCACAAAAGTTAAAGATACTAATATTTTTCCATATACTGGTG
TAGTTGCTTTTAAAAGTGCAACTGGATTTGTAGTTGGAAAGAATACTATTTTAACAAATAAACATGTGTCGAAAAATTAC
AAAGTGGGCGATCGTATTACTGCACATCCAAATAGTGATAAAGGTAATGGTGGTATTTATTCGATTAAAAAGATTATTAA
TTATCCAGGTAAAGAAGATGTATCAGTCATTCAAGTTGAAGAGCGTGCAATAGAACGTGGACCAAAAGGCTTTAATTTTA
ATGATAATGTAACGCCATTCAAATATGCGGCAGGGGCTAAAGCTGGTGAGCGAATTAAAGTGATTGGTTATCCACACCCA
TACAAAAATAAATATGTTTTATATGAGTCAACTGGCCCTGTGATGTCAGTAGAAGGTAGCAGTATTGTATATTCAGCGCA
TACTGAAAGCGGAAACTCTGGATCACCTGTATTAAACAGCAACAACGAATTAGTTGGTATTCATTTTGCTTCTGATGTAA
AAAATGATGATAACAGAAATGCATATGGCGTCTACTTTACACCAGAAATTAAAAAATTCATTGCAGAAAACATAGATAAA
TAA

Upstream 100 bases:

>100_bases
TGATTTTTTAAAGAGTGATTAAGAAAACGGTTACATAATTAACTAAATATACTGAATTATGTATCTAGATATCAAAATAA
TTAAAAGAGAGGAACTTAAA

Downstream 100 bases:

>100_bases
ACAAATTGACTTTAAACGAGCGTTGCAACATATCTCGAATTGTAAAGGAGCTTGAAAATGAATAAAAATATAGTCATTAA
AAGCATGGCAGCATTAGCCA

Product: serine protease SplB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNY
KVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHP
YKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK

Sequences:

>Translated_240_residues
MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNY
KVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHP
YKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
>Mature_240_residues
MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNY
KVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHP
YKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK

Specific function: Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln [H]

COG id: COG3591

COG function: function code E; V8-like Glu-specific endopeptidase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003
- InterPro:   IPR000126
- InterPro:   IPR001254
- InterPro:   IPR008256
- InterPro:   IPR008353 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: NA

Molecular weight: Translated: 26097; Mature: 26097

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00672 V8_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSA
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECC
TGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVE
CCEEEECCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHCCCCCCCCEEEEEH
ERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGS
HHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCEEEECCC
SIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
EEEEEEECCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHCCC
>Mature Secondary Structure
MNKNVVIKSLAALTILTSVTGIGTTLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSA
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECC
TGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVE
CCEEEECCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHCCCCCCCCEEEEEH
ERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGS
HHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCEEEECCC
SIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
EEEEEEECCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA