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The map label for this gene is splA

Identifier: 57650604

GI number: 57650604

Start: 1920785

End: 1921501

Strand: Reverse

Name: splA

Synonym: SACOL1869

Alternate gene names: 57650604

Gene position: 1921501-1920785 (Counterclockwise)

Preceding gene: 57650606

Following gene: 57650603

Centisome position: 68.39

GC content: 31.94

Gene sequence:

>717_bases
ATGAATAAAAATGTAATGGTTAAAGGTTTAACTGCTTTAACTATTTTAACTATTTTAACATCTCTTGGTTTTGCTGAAAA
TATTTCTAATCAGCCTCATTCAATTGCCAAAGCAGAAAAGAATGTCAAAGAAATTACCGATGCAACTAAGGAACCATACA
ATTCAGTGGTAGCATTTGTGGGTGGTACTGGTGTAGTTGTTGGTAAAAATACAATCGTAACTAACAAACATATCGCTAAA
AGTAATGATATTTTTAAAAATAGAGTATCAGCACATCATTCGAGTAAAGGTAAAGGCGGAGGAAACTACGACGTTAAAGA
CATTGTAGAATATCCCGGAAAAGAAGACCTTGCGATAGTTCATGTTCATGAAACAAGTACAGAAGGTTTGAATTTTAATA
AGAACGTTAGTTATACAAAATTTGCAGACGGAGCAAAAGTGAAAGATAGAATTTCTGTTATTGGTTATCCAAAGGGTGCA
CAAACAAAATATAAAATGTTTGAATCGACAGGAACGATTAACCATATCAGTGGAACGTTTATGGAATTTGATGCGTATGC
ACAACCAGGTAATTCAGGATCTCCTGTATTGAATTCTAAACATGAACTGATTGGTATTTTATATGCAGGTAGTGGAAAAG
ATGAATCTGAAAAGAATTTCGGTGTTTATTTCACACCACAATTAAAAGAATTTATTCAAAATAATATTGAAAAATAA

Upstream 100 bases:

>100_bases
GGTTAATTAATATTTAATTAATATTTTTATTTAAAATGTATATAGTAAATGTGTATCTAGATACATTAACTATAAAAATA
AATTTGGAAGGAGGTAAAAT

Downstream 100 bases:

>100_bases
GTATCATCAATTCATTCGTGAAGTTGATTTTTTAAAGAGTGATTAAGAAAACGGTTACATAATTAACTAAATATACTGAA
TTATGTATCTAGATATCAAA

Product: serine protease SplA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAK
SNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGA
QTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK

Sequences:

>Translated_238_residues
MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAK
SNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGA
QTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
>Mature_238_residues
MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAK
SNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGA
QTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK

Specific function: Unknown

COG id: COG3591

COG function: function code E; V8-like Glu-specific endopeptidase

Gene ontology:

Cell location: Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPLA_STAAC (Q5HEW0)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186697.1
- HSSP:   Q53782
- ProteinModelPortal:   Q5HEW0
- SMR:   Q5HEW0
- STRING:   Q5HEW0
- EnsemblBacteria:   EBSTAT00000008749
- GeneID:   3237977
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1869
- TIGR:   SACOL1869
- eggNOG:   COG3591
- GeneTree:   EBGT00050000023734
- HOGENOM:   HBG693141
- OMA:   TINHING
- ProtClustDB:   CLSK885576
- BioCyc:   SAUR93062:SACOL1869-MONOMER
- GO:   GO:0006508
- InterPro:   IPR009003
- InterPro:   IPR000126
- InterPro:   IPR001254
- InterPro:   IPR008256
- InterPro:   IPR008353
- PRINTS:   PR01774
- PRINTS:   PR00839

Pfam domain/function: PF00089 Trypsin; SSF50494 Pept_Ser_Cys

EC number: NA

Molecular weight: Translated: 25877; Mature: 25877

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00672 V8_HIS; PS00673 V8_SER

Important sites: ACT_SITE 77-77 ACT_SITE 116-116 ACT_SITE 192-192

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFV
CCCCEEEHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEE
GGTGVVVGKNTIVTNKHIAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIV
CCCEEEEECCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCEEEE
HVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGAQTKYKMFESTGTINHISGTF
EEECCCCCCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEECCCCE
MEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
EEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHCCC
>Mature Secondary Structure
MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFV
CCCCEEEHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEE
GGTGVVVGKNTIVTNKHIAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIV
CCCEEEEECCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCEEEE
HVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGAQTKYKMFESTGTINHISGTF
EEECCCCCCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEECCCCE
MEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
EEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA