Click here to switch to the map view.

The map label for this gene is infC

Identifier: 57650552

GI number: 57650552

Start: 1757041

End: 1757568

Strand: Reverse

Name: infC

Synonym: SACOL1727

Alternate gene names: 57650552

Gene position: 1757568-1757041 (Counterclockwise)

Preceding gene: 57650553

Following gene: 57650551

Centisome position: 62.56

GC content: 34.85

Gene sequence:

>528_bases
GTGTCAACCATAGCAAAAGATCAAACTCAAATCAATGACAAAATTCGTGCAAAAGAATTACGTTTAATCGGTCAAGATGG
TGAACAAATTGGTGTTAAATCAAAGCGTGAAGCTTTAGAAATGGCTGAACGTGTAGATTTAGACTTAGTGGTCGTTGCAC
CGAATGCGAAACCACCAGTTGCAAGAATTATGGATTACGGTAAATTCAAATTCGAACAACAGAAAAAAGAAAAAGAAATG
AAAAAGAAACAAAAAATTATCAATGTTAAAGAAATTCGTTTAAGTCCAACAATTGAGGAACATGATTTCCAAACGAAGTT
GAAAAACGGACGTAAATTCTTAACTAAAGGCGATAAATGTAAAGTATCTATTCGTTTCAGAGGGCGTGCCATTACGCATA
AGGAAATTGGTCAACGTGTGCTAGAAAAATATGCAGATGAATGCAAAGATATAGCAACAGTTGAACAAAAACCTAAAATG
GACGGGCGTCAAATGTTTATCATGTTAGCGCCAACAGCTGAAAAATAA

Upstream 100 bases:

>100_bases
CAGGTTAATCACATTACACATAACTGTGTATAAGGAAGAGCGGGTATTTTATACCTGCTCTTCCTTTTTGCTTGGTGCAA
ATTTCGTAAAAATTTTGGAG

Downstream 100 bases:

>100_bases
TTAAAGCTATTACAGGAGGACTTATATTATGCCAAAAATGAAAACTCACCGCGGAGCAGCTAAACGTGTTAAAAGAACTG
CTTCAGGTCAATTAAAACGT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEM
KKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKM
DGRQMFIMLAPTAEK

Sequences:

>Translated_175_residues
MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEM
KKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKM
DGRQMFIMLAPTAEK
>Mature_174_residues
STIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMK
KKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMD
GRQMFIMLAPTAEK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=53.0487804878049, Blast_Score=163, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_STAA3 (Q2FG56)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494322.1
- ProteinModelPortal:   Q2FG56
- STRING:   Q2FG56
- EnsemblBacteria:   EBSTAT00000037564
- GeneID:   3913793
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_1627
- eggNOG:   COG0290
- GeneTree:   EBGT00050000024755
- HOGENOM:   HBG744268
- OMA:   FDRRAPV
- ProtClustDB:   PRK00028
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20214; Mature: 20083

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPV
CCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCH
ARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKC
HHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHCCCEECCCCCEE
KVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
STIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPV
CCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCH
ARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKC
HHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHCCCEECCCCCEE
KVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA