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The map label for this gene is uvrX [H]

Identifier: 57650368

GI number: 57650368

Start: 1410032

End: 1411294

Strand: Direct

Name: uvrX [H]

Synonym: SACOL1400

Alternate gene names: 57650368

Gene position: 1410032-1411294 (Clockwise)

Preceding gene: 57650366

Following gene: 57650370

Centisome position: 50.19

GC content: 33.81

Gene sequence:

>1263_bases
GTGTATAATTATCATTTATTAGAAGATAGGGATGTTCTATGTATTGACCAAAAAAGTTTTTTTGCGAGTGTTTCTTGTAT
TGAAAAGGGGCTAGATCCATTAGAAACAAAGCTAGCTGTTGTTGCAGATACTAAGCGTCAGGGTTCTGTAATATTGGCTG
CGACACCTAAATTAAAAGAATTAGGCATCAAGACAGGGTCGCGATTGTTTGAAATACCACATAGAAATGATATTTACATT
ATCAATCCAAGTATGCGTAAATATCTTAATGTTTCAGTTGCTATTTCTAAGATTGCATTGCGTTATATTCCACCTGAAGA
TTTACACCAATATAGTATTGACGAATTTTTTATGGATGTTACTGATAGCTATCATAGATTTAGTTCTACAGTACATGCAT
TTTGCGAAAGACTTAAACGTGAAATTTATGAAGAAACAGGCATTTATTGTACTGTGGGCATTGGTTCTAATATGTTATTA
AGTAAAATTGCTATGGATGTTGAAGCGAAGCATAGTCAAAATGGTATAGCTGAATGGCGATATCAAGATGTACCAACGAA
ATTATGGCCAATTCAGCCCTTGCGAGATTTTTGGGGTATTAATCGTCGAACAGAAGCCAAATTGAATAAAAGAGGAATTT
TTACTATAGGAGATTTAGCGAAATATCCATATAAATTTTTAAAAAAAGAGTTCGGTATTTTAGGTGTTGATATGCATCTA
CATGCGAATGGGATAGATCAGAGTAAAGTACGTGAAAAGCACAAGATCAGCAATCCATCGATATGCAAAAGTCAAATATT
AATGAGAGATTATCATTTTGATGAAGCAAAAGTAGTAATGCAAGAGTTAATTGAAGATGTTGCTAGCAGAGTTCGAGCAA
GAAAAAAAGTGGCAAGAACGATACATTTTGCCTTTGGCTATAGTGATGAAGGCGGTGTACATAAGCAATATACTTTGAAA
GATCCAACAAACTTAGAAAAAGATATTTATAAAGTAGTAATGCATTTCGCAGATAAATTATGTAATAAACAAGCACTATA
TCGTACGCTAAGTATATCTTTGAGTCAATTTATTAATGAGGATGAGCGACAGTTAAGTCTGTTTGAAGATGAATACCAAC
GCAAACGTGACGAATGTCTAGCTAAAACGATAGACCAATTACATTTGAAATACGGCAAAGGTATTGTGTCCAAAGCAGTA
TCGTTTACAGAAGCAGGTACAAAACACGGCAGATTAGGTTTAATGGCTGGACATAAAATGTAA

Upstream 100 bases:

>100_bases
TTAAAAATTCATTTGCAAAATAACAGAACATTTGTTCTAAAATAGTTGAAATAGAACACGTGTTCGTATATAATAAGATT
CAAGTAAGGGAGGAATAACA

Downstream 100 bases:

>100_bases
TGACTATACGGTTTAAGTAATATATAACTGTGATTCGTATAAAATAAGTCTCTAAAGATAAATATTTCATATATCACAAT
AGATTTTCACAATAATATCT

Product: ImpB/MucB/SamB family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADTKRQGSVILAATPKLKELGIKTGSRLFEIPHRNDIYI
INPSMRKYLNVSVAISKIALRYIPPEDLHQYSIDEFFMDVTDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLL
SKIAMDVEAKHSQNGIAEWRYQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGDLAKYPYKFLKKEFGILGVDMHL
HANGIDQSKVREKHKISNPSICKSQILMRDYHFDEAKVVMQELIEDVASRVRARKKVARTIHFAFGYSDEGGVHKQYTLK
DPTNLEKDIYKVVMHFADKLCNKQALYRTLSISLSQFINEDERQLSLFEDEYQRKRDECLAKTIDQLHLKYGKGIVSKAV
SFTEAGTKHGRLGLMAGHKM

Sequences:

>Translated_420_residues
MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADTKRQGSVILAATPKLKELGIKTGSRLFEIPHRNDIYI
INPSMRKYLNVSVAISKIALRYIPPEDLHQYSIDEFFMDVTDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLL
SKIAMDVEAKHSQNGIAEWRYQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGDLAKYPYKFLKKEFGILGVDMHL
HANGIDQSKVREKHKISNPSICKSQILMRDYHFDEAKVVMQELIEDVASRVRARKKVARTIHFAFGYSDEGGVHKQYTLK
DPTNLEKDIYKVVMHFADKLCNKQALYRTLSISLSQFINEDERQLSLFEDEYQRKRDECLAKTIDQLHLKYGKGIVSKAV
SFTEAGTKHGRLGLMAGHKM
>Mature_420_residues
MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADTKRQGSVILAATPKLKELGIKTGSRLFEIPHRNDIYI
INPSMRKYLNVSVAISKIALRYIPPEDLHQYSIDEFFMDVTDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLL
SKIAMDVEAKHSQNGIAEWRYQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGDLAKYPYKFLKKEFGILGVDMHL
HANGIDQSKVREKHKISNPSICKSQILMRDYHFDEAKVVMQELIEDVASRVRARKKVARTIHFAFGYSDEGGVHKQYTLK
DPTNLEKDIYKVVMHFADKLCNKQALYRTLSISLSQFINEDERQLSLFEDEYQRKRDECLAKTIDQLHLKYGKGIVSKAV
SFTEAGTKHGRLGLMAGHKM

Specific function: Involved In Uv Protection And Mutation. Essential For Induced (Or Sos) Mutagenesis. May Modify The DNA Replication Machinery To Allow Bypass Synthesis Across A Damaged Template. [C]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=400, Percent_Identity=24.5, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786425, Length=289, Percent_Identity=25.6055363321799, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 48428; Mature: 48428

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADTKRQGSVILAATPKLKE
CCCCEEECCCCEEEECCHHHHHHHHHHHHCCCHHHHCEEEEEECCCCCCEEEEECCCHHH
LGIKTGSRLFEIPHRNDIYIINPSMRKYLNVSVAISKIALRYIPPEDLHQYSIDEFFMDV
HCCCCCCCEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLLSKIAMDVEAKHSQNGIAEWR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCHHCE
YQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGDLAKYPYKFLKKEFGILGVDMHL
ECCCCCCCCCCCHHHHHHCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHCCEEEEEEEE
HANGIDQSKVREKHKISNPSICKSQILMRDYHFDEAKVVMQELIEDVASRVRARKKVART
ECCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IHFAFGYSDEGGVHKQYTLKDPTNLEKDIYKVVMHFADKLCNKQALYRTLSISLSQFINE
HHHEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DERQLSLFEDEYQRKRDECLAKTIDQLHLKYGKGIVSKAVSFTEAGTKHGRLGLMAGHKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCCC
>Mature Secondary Structure
MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADTKRQGSVILAATPKLKE
CCCCEEECCCCEEEECCHHHHHHHHHHHHCCCHHHHCEEEEEECCCCCCEEEEECCCHHH
LGIKTGSRLFEIPHRNDIYIINPSMRKYLNVSVAISKIALRYIPPEDLHQYSIDEFFMDV
HCCCCCCCEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLLSKIAMDVEAKHSQNGIAEWR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCHHCE
YQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGDLAKYPYKFLKKEFGILGVDMHL
ECCCCCCCCCCCHHHHHHCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHCCEEEEEEEE
HANGIDQSKVREKHKISNPSICKSQILMRDYHFDEAKVVMQELIEDVASRVRARKKVART
ECCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IHFAFGYSDEGGVHKQYTLKDPTNLEKDIYKVVMHFADKLCNKQALYRTLSISLSQFINE
HHHEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DERQLSLFEDEYQRKRDECLAKTIDQLHLKYGKGIVSKAVSFTEAGTKHGRLGLMAGHKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]