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The map label for this gene is msrR

Identifier: 57650366

GI number: 57650366

Start: 1408628

End: 1409611

Strand: Direct

Name: msrR

Synonym: SACOL1398

Alternate gene names: 57650366

Gene position: 1408628-1409611 (Clockwise)

Preceding gene: 57650364

Following gene: 57650368

Centisome position: 50.14

GC content: 33.23

Gene sequence:

>984_bases
ATGGATAAAGAAACTAATGACAACGAATATAGACGTCAAAGTGAACATCGCACTTCGGCGCCTAAGCGAAAAAAGAAGAA
GAAAATTAGGAAATTACCTATCATTCTTCTGATTGTTGTAATTTTACTTATCGCATTAGTTGTATATATTGTACATAGTT
ACAATAGCGGTGTAGAATATGCCAAGAAACATGCGAAAGATGTTAAAGTACATCAATTTAATGGACCAGTAAAAAATGAT
GGTAAAATTTCTATTCTTGTACTCGGTGCAGATAAAGCACAAGGTGGACAATCAAGAACAGATTCTATCATGGTTGTTCA
ATATGACTTTATCAATAAAAAGATGAAAATGATGTCTGTCATGCGTGATATTTATGCAGATATTCCAGGATATGGAAAAC
ACAAAATTAATTCAGCATACGCTTTAGGTGGTCCAGAGCTACTTAGAAAAACACTTGATAAAAATTTAGGAATTAATCCT
GAATATTATGCAGTAGTTGATTTTACTGGATTTGAGAAAATGATTGATGAATTAATGCCTGAAGGTGTACCAATTAATGT
CGAAAAAGATATGTCGAAAAATATTGGTGTATCTTTGAAAAAGGGTAACCATAGGTTGAATGGTAAAGAATTACTTGGTT
ATGCAAGATTCCGTCACGACCCTGAAGGTGACTTCGGACGCGTGCGACGTCAGCAACAAGTGATGCAAACATTGAAAAAA
GAAATGGTTAATTTTAGAACAGTTGTTAAATTACCAAAAGTTGCAGGTATTTTAAGAGGCTATGTGAATACAAACATTCC
TGATTCAGGGATTTTCCAAACAGGTTTGAGTTTTGGTATCCGAGGTGAAAAAGATGTTAAGTCATTGACTGTGCCAATCA
AGAACTCATACGAAGATGTCAATACAAATACTGATGGTAGTGCATTACAGATTAATAAAAACACAAATAAACAAGCTATT
AAAGACTTTTTAGATGAAGATTAA

Upstream 100 bases:

>100_bases
TTAAGAAATCACTTGCTTTTTGAATTGTTTTTATATAACGTTAATATGTGATTATTATAGTACACAAAAATCTATTTTTG
AAGATATAAGGTAGGTAAAT

Downstream 100 bases:

>100_bases
AAATAAACAAGGCGATTTCTATCATACTCAGATAGAAGTCGCCTTGTTCGTTTTCAAAGAATTAATTGGCATGCATCTTA
TGAAGAATTATTGATCTGAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKND
GKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINP
EYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKK
EMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAI
KDFLDED

Sequences:

>Translated_327_residues
MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKND
GKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINP
EYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKK
EMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAI
KDFLDED
>Mature_327_residues
MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKND
GKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINP
EYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKK
EMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAI
KDFLDED

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRR_STAA8 (Q7BHL7)

Other databases:

- EMBL:   AF311784
- EMBL:   CP000253
- RefSeq:   YP_499888.1
- STRING:   Q7BHL7
- EnsemblBacteria:   EBSTAT00000029807
- GeneID:   3920066
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_01361
- eggNOG:   COG1316
- GeneTree:   EBGT00050000023898
- HOGENOM:   HBG343543
- OMA:   ARRPIDT
- ProtClustDB:   CLSK885300
- BioCyc:   SAUR93061:SAOUHSC_01361-MONOMER
- GO:   GO:0006350
- InterPro:   IPR004474
- TIGRFAMs:   TIGR00350

Pfam domain/function: PF03816 LytR_cpsA_psr

EC number: NA

Molecular weight: Translated: 36971; Mature: 36971

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xeb07bc8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEY
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSV
HHHHHHCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
MRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINPEYYAVVDFTGFEKMIDELMP
HHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHCC
EGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKK
CCCCCCCHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
EMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHEEECCCCCCCCC
NTNTDGSALQINKNTNKQAIKDFLDED
CCCCCCCEEEEECCCCHHHHHHHHCCH
>Mature Secondary Structure
MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEY
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSV
HHHHHHCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
MRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINPEYYAVVDFTGFEKMIDELMP
HHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHCC
EGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKK
CCCCCCCHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
EMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHHEEECCCCCCCCC
NTNTDGSALQINKNTNKQAIKDFLDED
CCCCCCCEEEEECCCCHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12878519