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The map label for this gene is qoxA [H]

Identifier: 57650253

GI number: 57650253

Start: 1077078

End: 1079066

Strand: Reverse

Name: qoxA [H]

Synonym: SACOL1069

Alternate gene names: 57650253

Gene position: 1079066-1077078 (Counterclockwise)

Preceding gene: 57650254

Following gene: 57650252

Centisome position: 38.41

GC content: 36.9

Gene sequence:

>1989_bases
ATGAATTTTCCATGGGATCAATTACTAGTTAAAGGTAACTGGATGATTACAATGGCACAAATTGGTGCCCCATTCTTAGT
TATTGGTTTAATCGCAGTAATTACTTACTTTAAATTATGGAAATATCTTTACAAAGAATGGTTCACATCTGTAGACCATA
AGAAAATCGGTGTTATGTATTTAATCTGTGCCGTATTAATGTTCGTCCGTGGTGGTATTGATGCGTTACTTATTCGTGCG
CAATTAACAGTACCTGATAACAAATTTTTAGAATCTAACCACTATAACGAAATTTTTAGTACACATGGTGTAATCATGAT
TATCTTCATGGCAATGCCATTTATCTTTGGTTTATGGAATATCGTTGTTCCATTACAAATTGGAGCACGTGATGTTGCAT
TCCCAGTATTAAACAACGTAAGTTTCTGGCTATTCTTTGCAGGTATGATTTTATTCAACCTGTCATTTATTATTGGTGGT
TCACCAGCAGCTGGTTGGACAAACTATGCGCCACTAGCAGGTGAATTCAGTCCTGGTCCGGGTGTTAACTATTACTTAAT
AGCTATACAAATTTCAGGGCTTGGTACCTTAGCTACAGGTATCAACTTCTTTGTAACAATTTTAAGATGTAAAACACCAA
CTATGAAGTTTATGCAAATGCCAATGTTTACAGTAACAACATTTATTACTACATTAATTGTTATTCTTGCTTTCCCTCCT
TTAACAGTAGCGTTAGCATTAATGACAACTGATAGAATATTTGACACAGCATTCTTCACAGTTGCACATGGCGGTATGCC
AATGCTTTGGGCTAACTTCTTCTGGGTATGGGGGCACCCTGAAGTTTATATCGTTATCCTTCCAGCATTTGGTATTTACT
CAGAAATTATCCCGACATTCGCTCGTAAGCGTTTATTCGGACATCAAAGTATGGTATGGGCAACTGCCGGTATCGCGTTC
CTTAGTTTCTTAGTTTGGGTTCACCATTTCTTCACAATGGGTAATGGTGCGTTAATCAACTCATTCTTCTCAATTTCAAC
AATGCTGATTGGTATTCCAACTGGTGTGAAATTGTTTAACTGGTTATTAACATTATATAAAGGACGTATTACATTTGAGT
CACCAATGCTATTCTCATTAGCATTTATCCCTAACTTCCTTTTAGGTGGTGTTACGGGTGTAATGTTAGCAATGGCATCA
GCTGACTATCAATATCACAATACGTACTTCTTAGTAGCTCACTTCCACTATACATTGGTTACTGGTGTTGTATTTGCCTG
CTTAGCTGGTTTAATCTTCTGGTATCCAAAGATGATGGGTTACAAATTAAACGAAACATTAAACAAATGGTGCTTCTGGT
TCTTCATGATCGGATTTAACGTTTGTTTCTTACCACAATTCATTCTTGGATTAGATGGTATGCCACGTCGTTTATACACT
TATATGCCATCAGATGGTTGGTTCTTATTAAACTTAATTTCAACTATCGGTGCATTATTAATGGCAATCGGATTCTTATT
CCTTGTTGTTAGTATCGTATACAGTCACTTCAAATCTCCACGTGAAGCAACTGGAGATAACTGGGATGGCCTTGGTCGTA
CTCTAGAGTGGACTACTGCATCAGCAATTCCACCTAAATACAACTTTGCCATTACACCAGATTGGAATGACTACGACACA
TTTGTTGATATGAAAGAACATGGTCGTCATTACTTAGACAACCATAATTACAAAGACATTCATATGCCAAACAATACTCC
TGTTGGATTCTGGATTGGTATCTTTATGACTATCGGCGGTTTCTTCTTAATTTTCGAAACTGTAATTCCAGCATTAATTT
GTTTATTCGGTATTTTTGGTACTATGATTTATCGCAGTTTCCAAATCGATCACGGATATCATATCCCTGCTGCTGAAGTT
GCAGAAACTGAAGCTAGATTAAGAGAAGCGCGTATTAAAGAAAGGGAGGCTGTAAGTCATGAGTCATGA

Upstream 100 bases:

>100_bases
ATGAGTTCAAGAAAGATGAATCGAAAAATGCGAAAGAAATGAAGAAAATTTCAAAAGATGCGCAAGATCAAGACAATGAT
GATCATGGAGGTGGACATTA

Downstream 100 bases:

>100_bases
TACAAACACTATTGATTCACGCACACATGAAGGCGAATTAAATAAGCTTGGCTTTTGGATTTTCATTACAGCCGAATTTG
CGTTATTCGGTACCCTATTT

Product: quinol oxidase subunit I

Products: NA

Alternate protein names: Quinol oxidase polypeptide I [H]

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLYKEWFTSVDHKKIGVMYLICAVLMFVRGGIDALLIRA
QLTVPDNKFLESNHYNEIFSTHGVIMIIFMAMPFIFGLWNIVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGG
SPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFMQMPMFTVTTFITTLIVILAFPP
LTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWVWGHPEVYIVILPAFGIYSEIIPTFARKRLFGHQSMVWATAGIAF
LSFLVWVHHFFTMGNGALINSFFSISTMLIGIPTGVKLFNWLLTLYKGRITFESPMLFSLAFIPNFLLGGVTGVMLAMAS
ADYQYHNTYFLVAHFHYTLVTGVVFACLAGLIFWYPKMMGYKLNETLNKWCFWFFMIGFNVCFLPQFILGLDGMPRRLYT
YMPSDGWFLLNLISTIGALLMAIGFLFLVVSIVYSHFKSPREATGDNWDGLGRTLEWTTASAIPPKYNFAITPDWNDYDT
FVDMKEHGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGGFFLIFETVIPALICLFGIFGTMIYRSFQIDHGYHIPAAEV
AETEARLREARIKEREAVSHES

Sequences:

>Translated_662_residues
MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLYKEWFTSVDHKKIGVMYLICAVLMFVRGGIDALLIRA
QLTVPDNKFLESNHYNEIFSTHGVIMIIFMAMPFIFGLWNIVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGG
SPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFMQMPMFTVTTFITTLIVILAFPP
LTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWVWGHPEVYIVILPAFGIYSEIIPTFARKRLFGHQSMVWATAGIAF
LSFLVWVHHFFTMGNGALINSFFSISTMLIGIPTGVKLFNWLLTLYKGRITFESPMLFSLAFIPNFLLGGVTGVMLAMAS
ADYQYHNTYFLVAHFHYTLVTGVVFACLAGLIFWYPKMMGYKLNETLNKWCFWFFMIGFNVCFLPQFILGLDGMPRRLYT
YMPSDGWFLLNLISTIGALLMAIGFLFLVVSIVYSHFKSPREATGDNWDGLGRTLEWTTASAIPPKYNFAITPDWNDYDT
FVDMKEHGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGGFFLIFETVIPALICLFGIFGTMIYRSFQIDHGYHIPAAEV
AETEARLREARIKEREAVSHES
>Mature_662_residues
MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLYKEWFTSVDHKKIGVMYLICAVLMFVRGGIDALLIRA
QLTVPDNKFLESNHYNEIFSTHGVIMIIFMAMPFIFGLWNIVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGG
SPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFMQMPMFTVTTFITTLIVILAFPP
LTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWVWGHPEVYIVILPAFGIYSEIIPTFARKRLFGHQSMVWATAGIAF
LSFLVWVHHFFTMGNGALINSFFSISTMLIGIPTGVKLFNWLLTLYKGRITFESPMLFSLAFIPNFLLGGVTGVMLAMAS
ADYQYHNTYFLVAHFHYTLVTGVVFACLAGLIFWYPKMMGYKLNETLNKWCFWFFMIGFNVCFLPQFILGLDGMPRRLYT
YMPSDGWFLLNLISTIGALLMAIGFLFLVVSIVYSHFKSPREATGDNWDGLGRTLEWTTASAIPPKYNFAITPDWNDYDT
FVDMKEHGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGGFFLIFETVIPALICLFGIFGTMIYRSFQIDHGYHIPAAEV
AETEARLREARIKEREAVSHES

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=507, Percent_Identity=40.2366863905325, Blast_Score=348, Evalue=6e-96,
Organism=Escherichia coli, GI1786634, Length=625, Percent_Identity=50.56, Blast_Score=617, Evalue=1e-178,
Organism=Saccharomyces cerevisiae, GI6226519, Length=477, Percent_Identity=39.622641509434, Blast_Score=356, Evalue=6e-99,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=38.5802469135802, Blast_Score=240, Evalue=6e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=31.9838056680162, Blast_Score=134, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014233
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.9.3.-

Molecular weight: Translated: 75230; Mature: 75230

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLYKEWFTSVDHKKIGVMY
CCCCHHHHEEECCEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LICAVLMFVRGGIDALLIRAQLTVPDNKFLESNHYNEIFSTHGVIMIIFMAMPFIFGLWN
HHHHHHHHHHCCHHHEEEEEEEECCCCHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHH
IVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGGSPAAGWTNYAPLAGEFSPGP
HHHHHEECCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFMQMPMFTVTTFITTLIVILAFPP
CCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
LTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWVWGHPEVYIVILPAFGIYSEIIPTF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCEEEEECCCEEEEEEEECHHHHHHHHHHH
ARKRLFGHQSMVWATAGIAFLSFLVWVHHFFTMGNGALINSFFSISTMLIGIPTGVKLFN
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHH
WLLTLYKGRITFESPMLFSLAFIPNFLLGGVTGVMLAMASADYQYHNTYFLVAHFHYTLV
HHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEHHHHHHHH
TGVVFACLAGLIFWYPKMMGYKLNETLNKWCFWFFMIGFNVCFLPQFILGLDGMPRRLYT
HHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEE
YMPSDGWFLLNLISTIGALLMAIGFLFLVVSIVYSHFKSPREATGDNWDGLGRTLEWTTA
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCC
SAIPPKYNFAITPDWNDYDTFVDMKEHGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGG
CCCCCCCCEEECCCCCCHHHHHHHHHCCCHHHCCCCCCEEECCCCCCHHHHHHHHHHHHH
FFLIFETVIPALICLFGIFGTMIYRSFQIDHGYHIPAAEVAETEARLREARIKEREAVSH
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ES
CC
>Mature Secondary Structure
MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLYKEWFTSVDHKKIGVMY
CCCCHHHHEEECCEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LICAVLMFVRGGIDALLIRAQLTVPDNKFLESNHYNEIFSTHGVIMIIFMAMPFIFGLWN
HHHHHHHHHHCCHHHEEEEEEEECCCCHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHH
IVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGGSPAAGWTNYAPLAGEFSPGP
HHHHHEECCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFMQMPMFTVTTFITTLIVILAFPP
CCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
LTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWVWGHPEVYIVILPAFGIYSEIIPTF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCEEEEECCCEEEEEEEECHHHHHHHHHHH
ARKRLFGHQSMVWATAGIAFLSFLVWVHHFFTMGNGALINSFFSISTMLIGIPTGVKLFN
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHH
WLLTLYKGRITFESPMLFSLAFIPNFLLGGVTGVMLAMASADYQYHNTYFLVAHFHYTLV
HHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEHHHHHHHH
TGVVFACLAGLIFWYPKMMGYKLNETLNKWCFWFFMIGFNVCFLPQFILGLDGMPRRLYT
HHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEE
YMPSDGWFLLNLISTIGALLMAIGFLFLVVSIVYSHFKSPREATGDNWDGLGRTLEWTTA
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCC
SAIPPKYNFAITPDWNDYDTFVDMKEHGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGG
CCCCCCCCEEECCCCCCHHHHHHHHHCCCHHHCCCCCCEEECCCCCCHHHHHHHHHHHHH
FFLIFETVIPALICLFGIFGTMIYRSFQIDHGYHIPAAEVAETEARLREARIKEREAVSH
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
ES
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA