| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is recB [H]
Identifier: 41410190
GI number: 41410190
Start: 4563657
End: 4565516
Strand: Reverse
Name: recB [H]
Synonym: MAP4092c
Alternate gene names: 41410190
Gene position: 4565516-4563657 (Counterclockwise)
Preceding gene: 41410191
Following gene: 41410189
Centisome position: 94.53
GC content: 72.53
Gene sequence:
>1860_bases GTGGTGCGCGCGGCGGCGGCGACGATGTTCTTCGGCGAGACCGCCGAGACGTTGGCGGCCGGCGGTGACGCGCTGACCGA CCGGATCGCCCAAACCTTGCGGGAGTGGGCCGGTCACTCCCGCGAACGCGGCGTCGCCGCCATCTTCGAGGCCGCCCAGC TGCTGGGGATGAGCAATCGGGTGCTCGGCTGGCAGGGCGGGGCGCGGCACATGACGGACCTGGCGCATCTCACCCAACTG CTGGGCGAGGTGGCCCACCGCGAACACCACAACCTGCCCGCGCTGCGCGACTGGCTGCGCCGGCAGCGCGACGAGCGAAG CGGCGCGCCGGAACGCAACCGCCGGTTGGACAGCGACGCCGCCGCCGTCCAGATCATGACCGTCTTCGTCAGCAAGGGGC TGCAGTACCCGATCGTGTACCTGCCGTTCGCGTTCCACCGCAACACCACCGACAGCGACGTGGTGCTGTTCCACGACGAG GACGGCACCCGCTGCCTGCACGTCGGCGGCAAGGACAGCCCCGACTTCAAAACCGTTGAGCGGCTTGGCCGTAAGGAGGA CGCCAGCGACGACAGCCGGCTGACGTACGTCGCGTTGACCCGAGCGCAGGCCCAGGTGGTGGCGTGGTGGTCACCGGCCT ACCACGAGCCCAACGGCGGCCTGTCCCGGCTGCTGCGGGGCCGCCGGCCCGGCGAGCCGGTGGTGCCGGACCGCTGCGAG CCGGCGAAGATCTCCGACGCGGATGCCCTGGCTCGGCTGCGCGAGTGGGAGGCGGCCGGCGGCCCGGTCATCGAGGAGTC GGTGCCGGCGCCGGCGCCGCCGCTGTCCGGTGTGCCGGTGCCGGCACGGCTGGAGAACCGCCACTTCCACCGCGGCATCG ACACCGGTTGGCGGCGCACCTCCTATTCCGGCCTGATCCGGCAGGCCCAGCCCAGCGGGGTGGGCAGCGAACCCGAGGCC GCCGGGCTCGACGACGAGGTCGGCGACATTCTTCTGGCCCCGGCGACATCCGTCGGCGATGTTGCCTCGCCGATGGCGGA CCTTCCGGCGGGCGCCACCTTCGGCACCCTGGTGCACGCCGTGCTGCAGACGGCCGACCCGTTCGCCCCCGACCTGGCCG CCGAGCTGACCGCCCGGATCCGGGAGCACTCGGTGTGGTGGCCGGTGGCCGCGACCCCCGAAGACATGGCCGCGGCGATG GTGCCGATGCACGACACACCGCTGGGCCCGCTGGCCGGCGGCCTGACGCTGCGCCGGATCGGGTTGTCGGATCGCCTGTG CGAGCTGGACTTCGAGCTGCCGCTGGCCGGCGGCGATCGGCGCTCGGCCCCGCCGGAGGTTCGGCTGGCCGATCTGTCGC CGCTGTTGCGCGCGCATCTGCCGGCCGACGACGTGCTGGCCTGCTACGCCGACCGGCTGACGGACCGCTCCCTCGGCGCC GAACCGCTGCGCGGATACCTGACCGGCTCGATCGACGCCGTGCTGCGGATCCCGGACGGGGCGGGGCACCGCTACCTGGT GGTGGACTACAAGACCAACCGGCTCGGTGATGCGCAGCACCCGCTGACCGCCGCCGATTACGACCGGCCCCGGATGGTGG AGGCGATGTTGCACTCGGATTATCCGCTGCAGGCGCTGCTGTACAGCGCTGTGCTGCACCGGTTCCTGCGCTGGCGGCTG GCCGGCTACGAGCCGGACCGCCATCTCGGCGGCATCCTCTATTTGTTCGTGCGGGGCATGTGCGGCCCCGACACGCCGGT GCGCGACGGTCACCCGTCGGGCGTCTTCGATTGGCGACCGCCGTCGTCGTTGATCACGGCGCTGTCCGACCTGCTGGATG CCCAGGGGGTGGCGGTGTGA
Upstream 100 bases:
>100_bases TCCCGCCGTCTACACCGGCAACTCCGACGTGTTCACCTCGCAGGCGGCCGAGGATTGACTGTGCCTGCTGGAGGCGTTCG ATCAGCCGCACCGGCCCGGC
Downstream 100 bases:
>100_bases CGGCGGACGTGTTGCCGGAGCGGGTGTTTGACGCCGGGCCGCTGCGCCCGTTCGCCGACGCCGGCATCTTCGAAGCAGCG GATGTCCGTGTGGCGCAACG
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 619; Mature: 619
Protein sequence:
>619_residues MVRAAAATMFFGETAETLAAGGDALTDRIAQTLREWAGHSRERGVAAIFEAAQLLGMSNRVLGWQGGARHMTDLAHLTQL LGEVAHREHHNLPALRDWLRRQRDERSGAPERNRRLDSDAAAVQIMTVFVSKGLQYPIVYLPFAFHRNTTDSDVVLFHDE DGTRCLHVGGKDSPDFKTVERLGRKEDASDDSRLTYVALTRAQAQVVAWWSPAYHEPNGGLSRLLRGRRPGEPVVPDRCE PAKISDADALARLREWEAAGGPVIEESVPAPAPPLSGVPVPARLENRHFHRGIDTGWRRTSYSGLIRQAQPSGVGSEPEA AGLDDEVGDILLAPATSVGDVASPMADLPAGATFGTLVHAVLQTADPFAPDLAAELTARIREHSVWWPVAATPEDMAAAM VPMHDTPLGPLAGGLTLRRIGLSDRLCELDFELPLAGGDRRSAPPEVRLADLSPLLRAHLPADDVLACYADRLTDRSLGA EPLRGYLTGSIDAVLRIPDGAGHRYLVVDYKTNRLGDAQHPLTAADYDRPRMVEAMLHSDYPLQALLYSAVLHRFLRWRL AGYEPDRHLGGILYLFVRGMCGPDTPVRDGHPSGVFDWRPPSSLITALSDLLDAQGVAV
Sequences:
>Translated_619_residues MVRAAAATMFFGETAETLAAGGDALTDRIAQTLREWAGHSRERGVAAIFEAAQLLGMSNRVLGWQGGARHMTDLAHLTQL LGEVAHREHHNLPALRDWLRRQRDERSGAPERNRRLDSDAAAVQIMTVFVSKGLQYPIVYLPFAFHRNTTDSDVVLFHDE DGTRCLHVGGKDSPDFKTVERLGRKEDASDDSRLTYVALTRAQAQVVAWWSPAYHEPNGGLSRLLRGRRPGEPVVPDRCE PAKISDADALARLREWEAAGGPVIEESVPAPAPPLSGVPVPARLENRHFHRGIDTGWRRTSYSGLIRQAQPSGVGSEPEA AGLDDEVGDILLAPATSVGDVASPMADLPAGATFGTLVHAVLQTADPFAPDLAAELTARIREHSVWWPVAATPEDMAAAM VPMHDTPLGPLAGGLTLRRIGLSDRLCELDFELPLAGGDRRSAPPEVRLADLSPLLRAHLPADDVLACYADRLTDRSLGA EPLRGYLTGSIDAVLRIPDGAGHRYLVVDYKTNRLGDAQHPLTAADYDRPRMVEAMLHSDYPLQALLYSAVLHRFLRWRL AGYEPDRHLGGILYLFVRGMCGPDTPVRDGHPSGVFDWRPPSSLITALSDLLDAQGVAV >Mature_619_residues MVRAAAATMFFGETAETLAAGGDALTDRIAQTLREWAGHSRERGVAAIFEAAQLLGMSNRVLGWQGGARHMTDLAHLTQL LGEVAHREHHNLPALRDWLRRQRDERSGAPERNRRLDSDAAAVQIMTVFVSKGLQYPIVYLPFAFHRNTTDSDVVLFHDE DGTRCLHVGGKDSPDFKTVERLGRKEDASDDSRLTYVALTRAQAQVVAWWSPAYHEPNGGLSRLLRGRRPGEPVVPDRCE PAKISDADALARLREWEAAGGPVIEESVPAPAPPLSGVPVPARLENRHFHRGIDTGWRRTSYSGLIRQAQPSGVGSEPEA AGLDDEVGDILLAPATSVGDVASPMADLPAGATFGTLVHAVLQTADPFAPDLAAELTARIREHSVWWPVAATPEDMAAAM VPMHDTPLGPLAGGLTLRRIGLSDRLCELDFELPLAGGDRRSAPPEVRLADLSPLLRAHLPADDVLACYADRLTDRSLGA EPLRGYLTGSIDAVLRIPDGAGHRYLVVDYKTNRLGDAQHPLTAADYDRPRMVEAMLHSDYPLQALLYSAVLHRFLRWRL AGYEPDRHLGGILYLFVRGMCGPDTPVRDGHPSGVFDWRPPSSLITALSDLLDAQGVAV
Specific function: Required for efficient DNA repair; it catalyzes the unwinding of double-stranded DNA and the cleavage of single- stranded DNA and it stimulates local genetic recombination. All of these activities require concomitant hydrolysis of ATP [H]
COG id: COG1074
COG function: function code L; ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI1789183, Length=643, Percent_Identity=29.0824261275272, Blast_Score=156, Evalue=5e-39,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR004586 - InterPro: IPR011604 - InterPro: IPR014016 - InterPro: IPR011335 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.1.11.5 [H]
Molecular weight: Translated: 67418; Mature: 67418
Theoretical pI: Translated: 6.04; Mature: 6.04
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVRAAAATMFFGETAETLAAGGDALTDRIAQTLREWAGHSRERGVAAIFEAAQLLGMSNR CCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC VLGWQGGARHMTDLAHLTQLLGEVAHREHHNLPALRDWLRRQRDERSGAPERNRRLDSDA EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHH AAVQIMTVFVSKGLQYPIVYLPFAFHRNTTDSDVVLFHDEDGTRCLHVGGKDSPDFKTVE HHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCEEEECCCCCCCCHHHHH RLGRKEDASDDSRLTYVALTRAQAQVVAWWSPAYHEPNGGLSRLLRGRRPGEPVVPDRCE HHCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCC PAKISDADALARLREWEAAGGPVIEESVPAPAPPLSGVPVPARLENRHFHRGIDTGWRRT CCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCCC SYSGLIRQAQPSGVGSEPEAAGLDDEVGDILLAPATSVGDVASPMADLPAGATFGTLVHA HHHHHHHHCCCCCCCCCCCCCCCCCHHCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHHH VLQTADPFAPDLAAELTARIREHSVWWPVAATPEDMAAAMVPMHDTPLGPLAGGLTLRRI HHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHCCCCCCCCCHHHCCCEEEEE GLSDRLCELDFELPLAGGDRRSAPPEVRLADLSPLLRAHLPADDVLACYADRLTDRSLGA CCCCCCEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC EPLRGYLTGSIDAVLRIPDGAGHRYLVVDYKTNRLGDAQHPLTAADYDRPRMVEAMLHSD HHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCC YPLQALLYSAVLHRFLRWRLAGYEPDRHLGGILYLFVRGMCGPDTPVRDGHPSGVFDWRP CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC PSSLITALSDLLDAQGVAV HHHHHHHHHHHHHCCCCCC >Mature Secondary Structure MVRAAAATMFFGETAETLAAGGDALTDRIAQTLREWAGHSRERGVAAIFEAAQLLGMSNR CCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC VLGWQGGARHMTDLAHLTQLLGEVAHREHHNLPALRDWLRRQRDERSGAPERNRRLDSDA EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHH AAVQIMTVFVSKGLQYPIVYLPFAFHRNTTDSDVVLFHDEDGTRCLHVGGKDSPDFKTVE HHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCEEEECCCCCCCCHHHHH RLGRKEDASDDSRLTYVALTRAQAQVVAWWSPAYHEPNGGLSRLLRGRRPGEPVVPDRCE HHCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCC PAKISDADALARLREWEAAGGPVIEESVPAPAPPLSGVPVPARLENRHFHRGIDTGWRRT CCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCCC SYSGLIRQAQPSGVGSEPEAAGLDDEVGDILLAPATSVGDVASPMADLPAGATFGTLVHA HHHHHHHHCCCCCCCCCCCCCCCCCHHCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHHH VLQTADPFAPDLAAELTARIREHSVWWPVAATPEDMAAAMVPMHDTPLGPLAGGLTLRRI HHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHCCCCCCCCCHHHCCCEEEEE GLSDRLCELDFELPLAGGDRRSAPPEVRLADLSPLLRAHLPADDVLACYADRLTDRSLGA CCCCCCEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC EPLRGYLTGSIDAVLRIPDGAGHRYLVVDYKTNRLGDAQHPLTAADYDRPRMVEAMLHSD HHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCC YPLQALLYSAVLHRFLRWRLAGYEPDRHLGGILYLFVRGMCGPDTPVRDGHPSGVFDWRP CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC PSSLITALSDLLDAQGVAV HHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]