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The map label for this gene is gpsA

Identifier: 41410159

GI number: 41410159

Start: 4522567

End: 4523565

Strand: Reverse

Name: gpsA

Synonym: MAP4061c

Alternate gene names: 41410159

Gene position: 4523565-4522567 (Counterclockwise)

Preceding gene: 41410160

Following gene: 41410158

Centisome position: 93.66

GC content: 69.17

Gene sequence:

>999_bases
ATGGCAGCTCAGATGCGTGAACCCAAAGTCGTTGTGCTCGGAGGCGGCTCCTGGGGCACCACCGTGGCGTCGATCTGTGC
GCGCCGCGGGCCGACGCTGCAGTGGGTGCGCTCGCGGGAGACCGCCGACGACATCAACGAGAACCACCGCAACAGCCGCT
ATCTGGGCAACGACGTGGTGCTGAGCGACACGCTGCGCGCCACCACCGATTTCTGCGAGGCGGCCAACACCGCCGACGTG
GTGGTGACGGGAGTCCCCTCGCACGGCTTTCGCGGGGTGCTCACCGAACTGGCGCGGGAATTGCGGCCGTGGGTGCCGGT
GGTGTCCTTGGTCAAAGGGCTCGAGCAGGGCACCAACATGCGGATGTCGCAGATCGTCGAGGAGGTGCTGCCCGGTCATC
CGGCGGGCATCCTGGCCGGGCCGAACATCGCGCGCGAGGTGGCCGAGGGCTACGCCGCCGCGGCGGTGCTGGCGATGCCC
GACCAGCATCTGGCGACCCGGCTGTCCGGGCTGTTCCGCACCCGGCGGTTCCGCGTCTACACCACCGACGACGTCGTCGG
GGCGGAGATGGCCGGGGCGCTGAAGAACGTGTTCGCCATCGCCGTGGGCATGGGGTATTCGCTGGGCATCGCGCTGGTGA
TCGCCCGCGCGCTGCGCGAGATGACCAAGCTGGGGGTGGCGATGGGCGGCAGCCCCGACACCTTCCCGGGACTGGCCGGA
CTCGGCGACCTCATCGTCACCTGCACCAGCCAGCGCAGCCGCAACCGGCACGTCGGCGAACAACTGGGCGCCGGCAAACC
GATCGACGAGATCATCGCGTCGATGAACCAGGTCGCCGAGGGCGTCAAAGCGGCCAGCGTGATCATGGAGTTCGGCCTGA
CCATGCCGATCGCCCGCGAAGTCGATGCGGTGATCAACCACGGCTCGACGGTCGAGCAGGCCTATCGGGGGCTGATCGCC
GAGGTTCCCGGCCACGAGGTGCACGGCTCCGGCTTCTGA

Upstream 100 bases:

>100_bases
GGGCCGCCGACCGGGCGGCGCTGGCCGGCTGATCGGCGGGCGCCGGGGCGAGTTGGTGAATTCCTTCTAAAACTCAGATG
TCGGCAATACGCTGATCGCC

Downstream 100 bases:

>100_bases
CCTGGGCGTCGCGCGGTGGCCGAATTCAAATCTTTGCGTTCTCTATGGGCCGGTCACGTCGGCTTGACCGGTGTTTGCCA
GCAAAATACCGTCAGTCCAG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2 [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAAQMREPKVVVLGGGSWGTTVASICARRGPTLQWVRSRETADDINENHRNSRYLGNDVVLSDTLRATTDFCEAANTADV
VVTGVPSHGFRGVLTELARELRPWVPVVSLVKGLEQGTNMRMSQIVEEVLPGHPAGILAGPNIAREVAEGYAAAAVLAMP
DQHLATRLSGLFRTRRFRVYTTDDVVGAEMAGALKNVFAIAVGMGYSLGIALVIARALREMTKLGVAMGGSPDTFPGLAG
LGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMNQVAEGVKAASVIMEFGLTMPIAREVDAVINHGSTVEQAYRGLIA
EVPGHEVHGSGF

Sequences:

>Translated_332_residues
MAAQMREPKVVVLGGGSWGTTVASICARRGPTLQWVRSRETADDINENHRNSRYLGNDVVLSDTLRATTDFCEAANTADV
VVTGVPSHGFRGVLTELARELRPWVPVVSLVKGLEQGTNMRMSQIVEEVLPGHPAGILAGPNIAREVAEGYAAAAVLAMP
DQHLATRLSGLFRTRRFRVYTTDDVVGAEMAGALKNVFAIAVGMGYSLGIALVIARALREMTKLGVAMGGSPDTFPGLAG
LGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMNQVAEGVKAASVIMEFGLTMPIAREVDAVINHGSTVEQAYRGLIA
EVPGHEVHGSGF
>Mature_331_residues
AAQMREPKVVVLGGGSWGTTVASICARRGPTLQWVRSRETADDINENHRNSRYLGNDVVLSDTLRATTDFCEAANTADVV
VTGVPSHGFRGVLTELARELRPWVPVVSLVKGLEQGTNMRMSQIVEEVLPGHPAGILAGPNIAREVAEGYAAAAVLAMPD
QHLATRLSGLFRTRRFRVYTTDDVVGAEMAGALKNVFAIAVGMGYSLGIALVIARALREMTKLGVAMGGSPDTFPGLAGL
GDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMNQVAEGVKAASVIMEFGLTMPIAREVDAVINHGSTVEQAYRGLIAE
VPGHEVHGSGF

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=291, Percent_Identity=31.2714776632302, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI24307999, Length=294, Percent_Identity=30.6122448979592, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1790037, Length=326, Percent_Identity=35.2760736196319, Blast_Score=179, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17507425, Length=314, Percent_Identity=28.9808917197452, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI32564399, Length=295, Percent_Identity=30.8474576271186, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32564403, Length=304, Percent_Identity=30.2631578947368, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI193210136, Length=302, Percent_Identity=30.1324503311258, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324513, Length=279, Percent_Identity=30.8243727598566, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320181, Length=292, Percent_Identity=29.1095890410959, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI22026922, Length=297, Percent_Identity=28.6195286195286, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136202, Length=292, Percent_Identity=30.1369863013699, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17136204, Length=292, Percent_Identity=30.1369863013699, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17136200, Length=292, Percent_Identity=30.1369863013699, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281362270, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45551945, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648969, Length=182, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 35221; Mature: 35090

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQMREPKVVVLGGGSWGTTVASICARRGPTLQWVRSRETADDINENHRNSRYLGNDVV
CCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCEE
LSDTLRATTDFCEAANTADVVVTGVPSHGFRGVLTELARELRPWVPVVSLVKGLEQGTNM
EHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
RMSQIVEEVLPGHPAGILAGPNIAREVAEGYAAAAVLAMPDQHLATRLSGLFRTRRFRVY
HHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEE
TTDDVVGAEMAGALKNVFAIAVGMGYSLGIALVIARALREMTKLGVAMGGSPDTFPGLAG
ECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMNQVAEGVKAASVIMEFGLTMPIARE
HHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VDAVINHGSTVEQAYRGLIAEVPGHEVHGSGF
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AAQMREPKVVVLGGGSWGTTVASICARRGPTLQWVRSRETADDINENHRNSRYLGNDVV
CCCCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCEE
LSDTLRATTDFCEAANTADVVVTGVPSHGFRGVLTELARELRPWVPVVSLVKGLEQGTNM
EHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
RMSQIVEEVLPGHPAGILAGPNIAREVAEGYAAAAVLAMPDQHLATRLSGLFRTRRFRVY
HHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEE
TTDDVVGAEMAGALKNVFAIAVGMGYSLGIALVIARALREMTKLGVAMGGSPDTFPGLAG
ECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMNQVAEGVKAASVIMEFGLTMPIARE
HHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VDAVINHGSTVEQAYRGLIAEVPGHEVHGSGF
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]