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The map label for this gene is fabH

Identifier: 41410126

GI number: 41410126

Start: 4489201

End: 4490208

Strand: Reverse

Name: fabH

Synonym: MAP4028c

Alternate gene names: 41410126

Gene position: 4490208-4489201 (Counterclockwise)

Preceding gene: 41410127

Following gene: 41410116

Centisome position: 92.97

GC content: 71.03

Gene sequence:

>1008_bases
ATGAAGCAGATTGCCGCGACCAGCGGGCCCACCAACATCGGCTTGCTCAGCGTCGGGTCGTACCGGCCGCAGCGCGTGGT
GACCAACGACGAGCTGTGCCAGAACATCGACTCCTCCGATGAGTGGATCTATTCGCGCACCGGCATCAAGACACGCCGAT
TCGCCGCGCGCGACGAGTCCACGGCCTCGATGGCGACCGAGGCCGGACGTGAGGCGATCGCCAAGGCCGGCCTGGAGGCG
TCAGACATCGACTGCGTCGTGGTGGCCACCAGCACCCATTTCCTGCAGACCCCGGCGTGCGGCCCGGCGGTCGCGGCCGC
GCTGGGCGCCACCGGAGTGCCCGCCTTCGACATCTCGGCCGGCTGCGCCGGCTTCGGCTACGCGCTGGGGGTGGCGGCCG
ACATGGTGCGCGGCGGCACGGCCGGCAAGGTGCTGGTGCTGGGGTCGGAGAAGCTGTCGCCCACGGTCGACATGACCGAC
CGCAGCAACTGCTTCATCTTCGCCGACGGCGCCGCGGGCGTGGTGGTGGGCGAGACGCCCACCCAGGGGATCGGGCCGAC
GGTGTGGGGCAGCGACGGCACCCAGGCCACCGCGATTCGCCAGGACATCGACTGGATGGACTACCTGGACCGGCCCACCG
GGCCGCGCCCGTTCCTGCGGCTGGAGGGCAGCGCGGTATTCCGTTGGGCCGCATTCGAGATGGGCAAGGTCGGCCAGCAG
GCGATGGACGCGGCGGGGGTGCGGCCCGACGAGATCGACGTGTTCCTGCCGCACCAGGCCAACAGCCGGATCAACGAGAT
CCTGGCCAAGAGCCTCGAGCTGCGGCCGGACGCGGTGATCGCCAACGACATCGAGCACACCGGCAACACCTCGGCGGCGT
CGATACCGCTGGCCATGGCCGAGGTGCTGGCCACCGGGGCGGCCAAGGCCGGCGACCTGGCGCTGCTGATCGGCTACGGC
GCGGGGTTGAGCTATACCGCGCAGGTGGTGCGGCTGCCGCCGGGCTGA

Upstream 100 bases:

>100_bases
TGACGTGGGGTACCTGACAGTGCGACCAGACGCAAAGGCGCCCGCGCACCGCGCTTTTGGGGTACTTTTGCGTCTGCTCG
GGGGATAGCGAAGGACCGCA

Downstream 100 bases:

>100_bases
GCCGTCACCGTTCGGGGGGCACGTCCCCGTGCAGCCGGGCCTGCAGCAACTCGCGCTCCCGGCGCCGCCGTTCGCCGGCG
ACGGCCAGCGCGGCGGTCGC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKQIAATSGPTNIGLLSVGSYRPQRVVTNDELCQNIDSSDEWIYSRTGIKTRRFAARDESTASMATEAGREAIAKAGLEA
SDIDCVVVATSTHFLQTPACGPAVAAALGATGVPAFDISAGCAGFGYALGVAADMVRGGTAGKVLVLGSEKLSPTVDMTD
RSNCFIFADGAAGVVVGETPTQGIGPTVWGSDGTQATAIRQDIDWMDYLDRPTGPRPFLRLEGSAVFRWAAFEMGKVGQQ
AMDAAGVRPDEIDVFLPHQANSRINEILAKSLELRPDAVIANDIEHTGNTSAASIPLAMAEVLATGAAKAGDLALLIGYG
AGLSYTAQVVRLPPG

Sequences:

>Translated_335_residues
MKQIAATSGPTNIGLLSVGSYRPQRVVTNDELCQNIDSSDEWIYSRTGIKTRRFAARDESTASMATEAGREAIAKAGLEA
SDIDCVVVATSTHFLQTPACGPAVAAALGATGVPAFDISAGCAGFGYALGVAADMVRGGTAGKVLVLGSEKLSPTVDMTD
RSNCFIFADGAAGVVVGETPTQGIGPTVWGSDGTQATAIRQDIDWMDYLDRPTGPRPFLRLEGSAVFRWAAFEMGKVGQQ
AMDAAGVRPDEIDVFLPHQANSRINEILAKSLELRPDAVIANDIEHTGNTSAASIPLAMAEVLATGAAKAGDLALLIGYG
AGLSYTAQVVRLPPG
>Mature_335_residues
MKQIAATSGPTNIGLLSVGSYRPQRVVTNDELCQNIDSSDEWIYSRTGIKTRRFAARDESTASMATEAGREAIAKAGLEA
SDIDCVVVATSTHFLQTPACGPAVAAALGATGVPAFDISAGCAGFGYALGVAADMVRGGTAGKVLVLGSEKLSPTVDMTD
RSNCFIFADGAAGVVVGETPTQGIGPTVWGSDGTQATAIRQDIDWMDYLDRPTGPRPFLRLEGSAVFRWAAFEMGKVGQQ
AMDAAGVRPDEIDVFLPHQANSRINEILAKSLELRPDAVIANDIEHTGNTSAASIPLAMAEVLATGAAKAGDLALLIGYG
AGLSYTAQVVRLPPG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=37.4233128834356, Blast_Score=200, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34748; Mature: 34748

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIAATSGPTNIGLLSVGSYRPQRVVTNDELCQNIDSSDEWIYSRTGIKTRRFAARDES
CCCCCCCCCCCCEEEEEECCCCCCEECCCHHHHHCCCCCCCEEEECCCCCHHHHCCCCCH
TASMATEAGREAIAKAGLEASDIDCVVVATSTHFLQTPACGPAVAAALGATGVPAFDISA
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHCCCCCCCEECCC
GCAGFGYALGVAADMVRGGTAGKVLVLGSEKLSPTVDMTDRSNCFIFADGAAGVVVGETP
CCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCCCCCEEEEECCCCEEEECCCC
TQGIGPTVWGSDGTQATAIRQDIDWMDYLDRPTGPRPFLRLEGSAVFRWAAFEMGKVGQQ
CCCCCCCEECCCCCCHHHHHHCCCHHHHHCCCCCCCCEEEECCCEEEEEEHHHHHHHHHH
AMDAAGVRPDEIDVFLPHQANSRINEILAKSLELRPDAVIANDIEHTGNTSAASIPLAMA
HHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCHHCCCCCCHHHHHHHHH
EVLATGAAKAGDLALLIGYGAGLSYTAQVVRLPPG
HHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCC
>Mature Secondary Structure
MKQIAATSGPTNIGLLSVGSYRPQRVVTNDELCQNIDSSDEWIYSRTGIKTRRFAARDES
CCCCCCCCCCCCEEEEEECCCCCCEECCCHHHHHCCCCCCCEEEECCCCCHHHHCCCCCH
TASMATEAGREAIAKAGLEASDIDCVVVATSTHFLQTPACGPAVAAALGATGVPAFDISA
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEECCCCCHHHHHHHCCCCCCCEECCC
GCAGFGYALGVAADMVRGGTAGKVLVLGSEKLSPTVDMTDRSNCFIFADGAAGVVVGETP
CCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCCCCCEEEEECCCCEEEECCCC
TQGIGPTVWGSDGTQATAIRQDIDWMDYLDRPTGPRPFLRLEGSAVFRWAAFEMGKVGQQ
CCCCCCCEECCCCCCHHHHHHCCCHHHHHCCCCCCCCEEEECCCEEEEEEHHHHHHHHHH
AMDAAGVRPDEIDVFLPHQANSRINEILAKSLELRPDAVIANDIEHTGNTSAASIPLAMA
HHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCHHCCCCCCHHHHHHHHH
EVLATGAAKAGDLALLIGYGAGLSYTAQVVRLPPG
HHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA