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The map label for this gene is yafV [C]

Identifier: 41410071

GI number: 41410071

Start: 4431626

End: 4432450

Strand: Reverse

Name: yafV [C]

Synonym: MAP3973c

Alternate gene names: 41410071

Gene position: 4432450-4431626 (Counterclockwise)

Preceding gene: 41410072

Following gene: 41410070

Centisome position: 91.77

GC content: 72.48

Gene sequence:

>825_bases
ATGCGAATCGCGCTGGCGCAGATCCTCAGCGGCACCGACCCCGCGGCGAACCTGGCGCTGGTCGGCGAATACACCCGCCG
GGCCGCCGGGGCGGGCGCGCGGCTGGTGGTGTTCCCCGAGGCCACCATGTGCCGGTTCGGTGTGCCGCTGGCGCCGATCG
CCGAGCCGGTCGACGGCCCCTGGGCCGACGGGGTGCGCCGCATCGCCACCGAGGCGAACGTCACCGTCATCGCCGGCATG
TTCACCCCGTCCGGCGACGGCCGCGTGAAAAACACACTGCTCGTGGCCAATTCGGACGACCAGGCGGTCACCCACTACGA
CAAGATCCACCTCTACGACGCATTCGGCTTCACCGAATCGCGCACCGTCGCGCCGGGCCGCGAGCCGGTGGTGGTCGGCG
TCGACGGGGTGCGGGTCGGGCTGAGCGTCTGCTACGACATCCGATTCCCCGAGCTCTACACCGAGCTGGCCCGCCGCGGC
GCCCAGCTGATCGCGGTCTGCGCGTCCTGGGGCGCGGGTCCCGGCAAACTCGACCAGTGGACCCTGCTGGCCCGCGCCCG
CGCGCTGGACTCGATGAGCTACATCGCCGCGGCCGGTCAGGCCGACCCCGGCGAGATCCTGTCCGCGTCGGGGGCGCCGA
CCGGGGTGGGCGGCAGTCTGGTCGCCTCGCCGCTGGGTGAGGTGGTCGCGTCGGCCGGCGCGCAGCCGCAGCTGGTGCTG
GCCGACATCGACGTCGACCGGGTCGCGCAGGCCCGCAAGACTATCGCGGCGCTCAGCAACCGCTCGGACTTTGCTCAGGT
TGGTAGGGCAGAATCGGTCGGGTGA

Upstream 100 bases:

>100_bases
ATCGCCCAAACCGCCTGAGCTCGCGCCTAAGCTGGATCGCCCGACTCCTCCTCGCGCCGCCGCGGCGGCGCGCATCGTCG
CCGGGCCTAAGCTGGCGCTC

Downstream 100 bases:

>100_bases
CGAACCCACAAGGACCCCCGAATCAGGACCCGTCGACGTGGGGCCGTCCCGCCAACCAGGGACCCTACGGCCAGCCTCCC
ACGGAACGGCCGACCGAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MRIALAQILSGTDPAANLALVGEYTRRAAGAGARLVVFPEATMCRFGVPLAPIAEPVDGPWADGVRRIATEANVTVIAGM
FTPSGDGRVKNTLLVANSDDQAVTHYDKIHLYDAFGFTESRTVAPGREPVVVGVDGVRVGLSVCYDIRFPELYTELARRG
AQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAAGQADPGEILSASGAPTGVGGSLVASPLGEVVASAGAQPQLVL
ADIDVDRVAQARKTIAALSNRSDFAQVGRAESVG

Sequences:

>Translated_274_residues
MRIALAQILSGTDPAANLALVGEYTRRAAGAGARLVVFPEATMCRFGVPLAPIAEPVDGPWADGVRRIATEANVTVIAGM
FTPSGDGRVKNTLLVANSDDQAVTHYDKIHLYDAFGFTESRTVAPGREPVVVGVDGVRVGLSVCYDIRFPELYTELARRG
AQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAAGQADPGEILSASGAPTGVGGSLVASPLGEVVASAGAQPQLVL
ADIDVDRVAQARKTIAALSNRSDFAQVGRAESVG
>Mature_274_residues
MRIALAQILSGTDPAANLALVGEYTRRAAGAGARLVVFPEATMCRFGVPLAPIAEPVDGPWADGVRRIATEANVTVIAGM
FTPSGDGRVKNTLLVANSDDQAVTHYDKIHLYDAFGFTESRTVAPGREPVVVGVDGVRVGLSVCYDIRFPELYTELARRG
AQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAAGQADPGEILSASGAPTGVGGSLVASPLGEVVASAGAQPQLVL
ADIDVDRVAQARKTIAALSNRSDFAQVGRAESVG

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=276, Percent_Identity=32.2463768115942, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI297632348, Length=276, Percent_Identity=31.1594202898551, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI297632350, Length=276, Percent_Identity=31.1594202898551, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI5031947, Length=276, Percent_Identity=31.1594202898551, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI297632346, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=274, Percent_Identity=29.5620437956204, Blast_Score=104, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6322335, Length=300, Percent_Identity=29, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323383, Length=277, Percent_Identity=28.5198555956679, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355835, Length=270, Percent_Identity=28.1481481481481, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI17933642, Length=273, Percent_Identity=27.8388278388278, Blast_Score=98, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28386; Mature: 28386

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALAQILSGTDPAANLALVGEYTRRAAGAGARLVVFPEATMCRFGVPLAPIAEPVDGP
CCEEHHHHHCCCCCCCCEEEEEHHHHHHCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCC
WADGVRRIATEANVTVIAGMFTPSGDGRVKNTLLVANSDDQAVTHYDKIHLYDAFGFTES
HHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCEEEEEEEEEEEECCCCCC
RTVAPGREPVVVGVDGVRVGLSVCYDIRFPELYTELARRGAQLIAVCASWGAGPGKLDQW
CCCCCCCCCEEEECCCHHEEEEHEEECCCHHHHHHHHHCCHHEEEHHHHCCCCCCCCHHH
TLLARARALDSMSYIAAAGQADPGEILSASGAPTGVGGSLVASPLGEVVASAGAQPQLVL
HHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
ADIDVDRVAQARKTIAALSNRSDFAQVGRAESVG
EECCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MRIALAQILSGTDPAANLALVGEYTRRAAGAGARLVVFPEATMCRFGVPLAPIAEPVDGP
CCEEHHHHHCCCCCCCCEEEEEHHHHHHCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCC
WADGVRRIATEANVTVIAGMFTPSGDGRVKNTLLVANSDDQAVTHYDKIHLYDAFGFTES
HHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCEEEEEEEEEEEECCCCCC
RTVAPGREPVVVGVDGVRVGLSVCYDIRFPELYTELARRGAQLIAVCASWGAGPGKLDQW
CCCCCCCCCEEEECCCHHEEEEHEEECCCHHHHHHHHHCCHHEEEHHHHCCCCCCCCHHH
TLLARARALDSMSYIAAAGQADPGEILSASGAPTGVGGSLVASPLGEVVASAGAQPQLVL
HHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
ADIDVDRVAQARKTIAALSNRSDFAQVGRAESVG
EECCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]