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The map label for this gene is moaA3

Identifier: 41410030

GI number: 41410030

Start: 4392319

End: 4393524

Strand: Reverse

Name: moaA3

Synonym: MAP3932c

Alternate gene names: 41410030

Gene position: 4393524-4392319 (Counterclockwise)

Preceding gene: 41410031

Following gene: 41410028

Centisome position: 90.97

GC content: 74.54

Gene sequence:

>1206_bases
ATGCGCTCCGTCGCCGAACACCAGCGGGTGGTGGCCGGGCTGATCCGCGCCCGGCCGCCGGTCGCGGTGCCGCTGGCGCA
GGCCCAGGGCCTGGTGCTGGCCGACGACGTGGTGGCGGGGCTGGCGCTGCCGGTGTTCGACAACTCCGCGATGGACGGCT
ACGCGGTGCGCGCCGAGGACACCGCGGGCGCCACCCCCGAGCGGCCGGTCGTGCTGCCGGTCGCCGAGGACATTCCGGCC
GGACGCACCGACGAGCTGACGCTGCAGCCGGGCACCGCGCACCGGATCATGACGGGCGCGCCGGTGCCGGCCGGGGCGAC
GGCCGTCGTGCCGGTGGAGGACACCGACGGCGGCGTGGACGTGGTGTCGATCCGGGCGTCGCGCGAACCCGGCAAGCACA
TCCGCCGCGCCGGCGAGGACGTCTCCCCCGGCACCACCGTGTTGCGCCGCGGGCAGGTAGTGACGCCGGCGGTGCTCGGG
CTGGCCGCGGCGCTGGGCATCGCCGAGCTGTCGGTGATCCCGCGGCAGCGGGTGCTGGTCATCTCGACGGGATCGGAGCT
GGTGGCCCCGGGCGCCGCGCTGCGGCCGGGGCAGATCTACGAGTCCAACTCGATCATGCTGGCCGGGGCCGTGCGCGACG
CCGGCGCGGAGCTGGTGGCCGTCGCGACCGCCGAGGACGAGGTGGCACAGTTCAGTTCGATCATCGACCGGTATGCGGCC
GGCACCGACCTGATCATCACCAGCGGCGGCGTCAGCGCCGGCGCCTACGAGGTGGTCAAGGACGCCTTCGGGCGCGAGGG
CGATCAGGGCGTGGAGTTCGTCAAGGTGGCCATGCAGCCGGGCATGCCGCAGGGCGTGGGACGGGTGGCCGGGGCGACCA
TCGTCACGCTGCCCGGCAATCCGGTCAGCGCGCTGGTGTCCTTCGAGGTGTTCATCCGCCCGGCGCTGCGCGCCGCGATG
GGCCTGCCCGATCCCGAACGCCCGCACCGGTCGGCGGTGCTCGCCGAGTCGCTCACCTCGCCGCGCGGCAAACGCCAATT
CCGCCGCGCGGTGCTGGACGACGACGCCGGCACCGTCGTCAGCTACGGCCCGCCGGCCTCGCATCACCTGCGCTGGCTGG
CGTCGGCGAACGGGCTGCTGGACATCCCCGAAGACGTCGTCGAGGTGCCCGAGGGGACCACCCTCGAGGTGTGGGATCTG
CGCTAG

Upstream 100 bases:

>100_bases
CCAGCGCCCAGTCGCACGACGAGCAGCTGCAGCGCCGGCTGTGGGCCGTGTCCGAAGAACTCACCGGCGTCCACTTCCCG
GTCTGACCTCCATGGCCGCG

Downstream 100 bases:

>100_bases
CCCGATTCAGCCGGCGGGCGCTCGATGGAATTCGTCGGCGGTGTCGAAGGCCGGGGTGTAGCGGATGGCGACGGCGACGA
CCGTCATCATCACCGGGATG

Product: MoaA3

Products: NA

Alternate protein names: MPT Mo-transferase 2 [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MRSVAEHQRVVAGLIRARPPVAVPLAQAQGLVLADDVVAGLALPVFDNSAMDGYAVRAEDTAGATPERPVVLPVAEDIPA
GRTDELTLQPGTAHRIMTGAPVPAGATAVVPVEDTDGGVDVVSIRASREPGKHIRRAGEDVSPGTTVLRRGQVVTPAVLG
LAAALGIAELSVIPRQRVLVISTGSELVAPGAALRPGQIYESNSIMLAGAVRDAGAELVAVATAEDEVAQFSSIIDRYAA
GTDLIITSGGVSAGAYEVVKDAFGREGDQGVEFVKVAMQPGMPQGVGRVAGATIVTLPGNPVSALVSFEVFIRPALRAAM
GLPDPERPHRSAVLAESLTSPRGKRQFRRAVLDDDAGTVVSYGPPASHHLRWLASANGLLDIPEDVVEVPEGTTLEVWDL
R

Sequences:

>Translated_401_residues
MRSVAEHQRVVAGLIRARPPVAVPLAQAQGLVLADDVVAGLALPVFDNSAMDGYAVRAEDTAGATPERPVVLPVAEDIPA
GRTDELTLQPGTAHRIMTGAPVPAGATAVVPVEDTDGGVDVVSIRASREPGKHIRRAGEDVSPGTTVLRRGQVVTPAVLG
LAAALGIAELSVIPRQRVLVISTGSELVAPGAALRPGQIYESNSIMLAGAVRDAGAELVAVATAEDEVAQFSSIIDRYAA
GTDLIITSGGVSAGAYEVVKDAFGREGDQGVEFVKVAMQPGMPQGVGRVAGATIVTLPGNPVSALVSFEVFIRPALRAAM
GLPDPERPHRSAVLAESLTSPRGKRQFRRAVLDDDAGTVVSYGPPASHHLRWLASANGLLDIPEDVVEVPEGTTLEVWDL
R
>Mature_401_residues
MRSVAEHQRVVAGLIRARPPVAVPLAQAQGLVLADDVVAGLALPVFDNSAMDGYAVRAEDTAGATPERPVVLPVAEDIPA
GRTDELTLQPGTAHRIMTGAPVPAGATAVVPVEDTDGGVDVVSIRASREPGKHIRRAGEDVSPGTTVLRRGQVVTPAVLG
LAAALGIAELSVIPRQRVLVISTGSELVAPGAALRPGQIYESNSIMLAGAVRDAGAELVAVATAEDEVAQFSSIIDRYAA
GTDLIITSGGVSAGAYEVVKDAFGREGDQGVEFVKVAMQPGMPQGVGRVAGATIVTLPGNPVSALVSFEVFIRPALRAAM
GLPDPERPHRSAVLAESLTSPRGKRQFRRAVLDDDAGTVVSYGPPASHHLRWLASANGLLDIPEDVVEVPEGTTLEVWDL
R

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=393, Percent_Identity=34.8600508905852, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI10880983, Length=389, Percent_Identity=34.7043701799486, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI1787049, Length=367, Percent_Identity=37.3297002724796, Blast_Score=199, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI25147659, Length=352, Percent_Identity=28.6931818181818, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17562606, Length=341, Percent_Identity=24.633431085044, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17136978, Length=379, Percent_Identity=27.7044854881267, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638841, Length=379, Percent_Identity=27.7044854881267, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 41554; Mature: 41554

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSVAEHQRVVAGLIRARPPVAVPLAQAQGLVLADDVVAGLALPVFDNSAMDGYAVRAED
CCCHHHHHHHHHHHHHCCCCCEEEHHHCCCEEEEHHHHHHEEEEEECCCCCCCEEEEECC
TAGATPERPVVLPVAEDIPAGRTDELTLQPGTAHRIMTGAPVPAGATAVVPVEDTDGGVD
CCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCCCCEEEEEECCCCCCEE
VVSIRASREPGKHIRRAGEDVSPGTTVLRRGQVVTPAVLGLAAALGIAELSVIPRQRVLV
EEEEECCCCCHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCEEEE
ISTGSELVAPGAALRPGQIYESNSIMLAGAVRDAGAELVAVATAEDEVAQFSSIIDRYAA
EECCCHHHCCCCCCCCCCEEECCCEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHCC
GTDLIITSGGVSAGAYEVVKDAFGREGDQGVEFVKVAMQPGMPQGVGRVAGATIVTLPGN
CCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHEEEEECCCCCCHHHHHHCCCEEEEECCC
PVSALVSFEVFIRPALRAAMGLPDPERPHRSAVLAESLTSPRGKRQFRRAVLDDDAGTVV
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEE
SYGPPASHHLRWLASANGLLDIPEDVVEVPEGTTLEVWDLR
ECCCCHHHHHEEECCCCCCCCCCHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MRSVAEHQRVVAGLIRARPPVAVPLAQAQGLVLADDVVAGLALPVFDNSAMDGYAVRAED
CCCHHHHHHHHHHHHHCCCCCEEEHHHCCCEEEEHHHHHHEEEEEECCCCCCCEEEEECC
TAGATPERPVVLPVAEDIPAGRTDELTLQPGTAHRIMTGAPVPAGATAVVPVEDTDGGVD
CCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCCCCEEEEEECCCCCCEE
VVSIRASREPGKHIRRAGEDVSPGTTVLRRGQVVTPAVLGLAAALGIAELSVIPRQRVLV
EEEEECCCCCHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCEEEE
ISTGSELVAPGAALRPGQIYESNSIMLAGAVRDAGAELVAVATAEDEVAQFSSIIDRYAA
EECCCHHHCCCCCCCCCCEEECCCEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHCC
GTDLIITSGGVSAGAYEVVKDAFGREGDQGVEFVKVAMQPGMPQGVGRVAGATIVTLPGN
CCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHEEEEECCCCCCHHHHHHCCCEEEEECCC
PVSALVSFEVFIRPALRAAMGLPDPERPHRSAVLAESLTSPRGKRQFRRAVLDDDAGTVV
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEE
SYGPPASHHLRWLASANGLLDIPEDVVEVPEGTTLEVWDLR
ECCCCHHHHHEEECCCCCCCCCCHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]