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The map label for this gene is yciC [H]

Identifier: 41409870

GI number: 41409870

Start: 4215635

End: 4216777

Strand: Reverse

Name: yciC [H]

Synonym: MAP3772c

Alternate gene names: 41409870

Gene position: 4216777-4215635 (Counterclockwise)

Preceding gene: 41409871

Following gene: 41409867

Centisome position: 87.31

GC content: 63.6

Gene sequence:

>1143_bases
ATGCCGCCACAGAGTTCTACGCCCCTCCCCGTCACCGTCCTATCCGGGTTCCTGGGAGCAGGCAAGACCACCCTGCTCAA
CCACGTCCTGGCTAACCAGGAAGGCCGCCGCGTCGCGGTCATCGTCAACGACATGAGCGAAGTGAACATCGACGCGGCGC
TGGTGGCCGGGACGGGTTTCCTGGACCGCACCGAAGAGAAACTGGTCGAACTGACCAACGGATGCATCTGCTGCACTTTG
CGTGAAGATCTCATCGAATCGGTCGCCCGCTTGGCATCCGCCGGGCGTTTCGATTACCTGCTGATCGAGTCGACAGGTAT
CTCCGAACCGATGCCGGTTGCTGCCAGCTTCAGTTGGGAATTCGAGAACGGATTCAGCCTCAGTCGGATCGCGCGACTCG
ACACCATGGTGACCGTGGTCGACGCGTCGACGTTTCTGCGCGAGCTTGCGCGCGGCGAAGCCCTGGCTGCCCGCCACCTA
GCCGCCGGGGACGGCGACGTCCGCACGATTGCCGACCTACTTGTCGATCAAGTGGAGTTCGCCGACGTGATTCTGCTCAA
CAAGACCGATCTGGTGAGTGAGAAAACCAACGCAACGGTGGCGGCAGTACTTCGGCGCCTTAATCCGGCGGCGAAGATCG
TCCCCACCGACCACGGCCGGGTAGCGCTGTCAGAGGTCCTGGACACCGGTCTATTCGATCCCCACCTTGCGGCCGAATCA
GCCGGCTGGGCGGAGGAACTCGCCAACGGGCACTCACCCGAGACCGAGGAATACGGCATCAGCAGTGTGACTTTCCGCGC
CGCGCGCCCTCTGCACCCGCAGCGATTACACGTAGCGCTGGGCCAGCTGCAGGGAGTGTTGCGCAGCAAAGGCTTCTGCT
GGATTGCCAGCCGACCGGACATTGCGGCCATCTGGTCCCAAGCCGGGCCCAACCTGGTGATAGAACCCGCCCAGTACTGG
TCAACCGCCGACTTTCCCGCCGGCCAAGAGATCGTGTTCATCGGGGTCAACCTCGACCACAGCCGGGTGCTCGACCTCAT
GCAGGCGGCGCTGCTGACCGACACCGAACTGGCCCAAGGTCCTCAGCGGTGGGTCGGCTACCCCGACCCGTTGCCACCGT
GGGACGTCGTTCACGCCCACTAA

Upstream 100 bases:

>100_bases
ACCTTTACGGCACATGTCCGCTTTGCCAAAACACACAACCGTGAGGACTCGGCGTTAGGAGCTTTGCGAGCGTTAATGAA
AATGATTATCATTAACGCTT

Downstream 100 bases:

>100_bases
ACGTCGAACGAATTCGATTACCTCGGAGTCACCATGATCCACACGCCCAACTACCGGCCCGCCGACCACCGATCGCGACG
CGAAATCGACCAGGCGATCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MPPQSSTPLPVTVLSGFLGAGKTTLLNHVLANQEGRRVAVIVNDMSEVNIDAALVAGTGFLDRTEEKLVELTNGCICCTL
REDLIESVARLASAGRFDYLLIESTGISEPMPVAASFSWEFENGFSLSRIARLDTMVTVVDASTFLRELARGEALAARHL
AAGDGDVRTIADLLVDQVEFADVILLNKTDLVSEKTNATVAAVLRRLNPAAKIVPTDHGRVALSEVLDTGLFDPHLAAES
AGWAEELANGHSPETEEYGISSVTFRAARPLHPQRLHVALGQLQGVLRSKGFCWIASRPDIAAIWSQAGPNLVIEPAQYW
STADFPAGQEIVFIGVNLDHSRVLDLMQAALLTDTELAQGPQRWVGYPDPLPPWDVVHAH

Sequences:

>Translated_380_residues
MPPQSSTPLPVTVLSGFLGAGKTTLLNHVLANQEGRRVAVIVNDMSEVNIDAALVAGTGFLDRTEEKLVELTNGCICCTL
REDLIESVARLASAGRFDYLLIESTGISEPMPVAASFSWEFENGFSLSRIARLDTMVTVVDASTFLRELARGEALAARHL
AAGDGDVRTIADLLVDQVEFADVILLNKTDLVSEKTNATVAAVLRRLNPAAKIVPTDHGRVALSEVLDTGLFDPHLAAES
AGWAEELANGHSPETEEYGISSVTFRAARPLHPQRLHVALGQLQGVLRSKGFCWIASRPDIAAIWSQAGPNLVIEPAQYW
STADFPAGQEIVFIGVNLDHSRVLDLMQAALLTDTELAQGPQRWVGYPDPLPPWDVVHAH
>Mature_379_residues
PPQSSTPLPVTVLSGFLGAGKTTLLNHVLANQEGRRVAVIVNDMSEVNIDAALVAGTGFLDRTEEKLVELTNGCICCTLR
EDLIESVARLASAGRFDYLLIESTGISEPMPVAASFSWEFENGFSLSRIARLDTMVTVVDASTFLRELARGEALAARHLA
AGDGDVRTIADLLVDQVEFADVILLNKTDLVSEKTNATVAAVLRRLNPAAKIVPTDHGRVALSEVLDTGLFDPHLAAESA
GWAEELANGHSPETEEYGISSVTFRAARPLHPQRLHVALGQLQGVLRSKGFCWIASRPDIAAIWSQAGPNLVIEPAQYWS
TADFPAGQEIVFIGVNLDHSRVLDLMQAALLTDTELAQGPQRWVGYPDPLPPWDVVHAH

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=367, Percent_Identity=30.5177111716621, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI126722884, Length=367, Percent_Identity=29.9727520435967, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI146231952, Length=367, Percent_Identity=30.2452316076294, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI148727351, Length=367, Percent_Identity=29.9727520435967, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI223941776, Length=356, Percent_Identity=29.4943820224719, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI223941779, Length=211, Percent_Identity=35.0710900473934, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI119120938, Length=146, Percent_Identity=36.3013698630137, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI87082430, Length=349, Percent_Identity=30.0859598853868, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788499, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324356, Length=232, Percent_Identity=28.448275862069, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41022; Mature: 40891

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPQSSTPLPVTVLSGFLGAGKTTLLNHVLANQEGRRVAVIVNDMSEVNIDAALVAGTGF
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCC
LDRTEEKLVELTNGCICCTLREDLIESVARLASAGRFDYLLIESTGISEPMPVAASFSWE
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEE
FENGFSLSRIARLDTMVTVVDASTFLRELARGEALAARHLAAGDGDVRTIADLLVDQVEF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ADVILLNKTDLVSEKTNATVAAVLRRLNPAAKIVPTDHGRVALSEVLDTGLFDPHLAAES
HCEEEECCCHHHCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCHHHHCC
AGWAEELANGHSPETEEYGISSVTFRAARPLHPQRLHVALGQLQGVLRSKGFCWIASRPD
CCHHHHHHCCCCCCCHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
IAAIWSQAGPNLVIEPAQYWSTADFPAGQEIVFIGVNLDHSRVLDLMQAALLTDTELAQG
HHHHHHCCCCCEEECCHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCHHHHCC
PQRWVGYPDPLPPWDVVHAH
CHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPQSSTPLPVTVLSGFLGAGKTTLLNHVLANQEGRRVAVIVNDMSEVNIDAALVAGTGF
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCC
LDRTEEKLVELTNGCICCTLREDLIESVARLASAGRFDYLLIESTGISEPMPVAASFSWE
HHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEE
FENGFSLSRIARLDTMVTVVDASTFLRELARGEALAARHLAAGDGDVRTIADLLVDQVEF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ADVILLNKTDLVSEKTNATVAAVLRRLNPAAKIVPTDHGRVALSEVLDTGLFDPHLAAES
HCEEEECCCHHHCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCHHHHCC
AGWAEELANGHSPETEEYGISSVTFRAARPLHPQRLHVALGQLQGVLRSKGFCWIASRPD
CCHHHHHHCCCCCCCHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
IAAIWSQAGPNLVIEPAQYWSTADFPAGQEIVFIGVNLDHSRVLDLMQAALLTDTELAQG
HHHHHHCCCCCEEECCHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCHHHHCC
PQRWVGYPDPLPPWDVVHAH
CHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]