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The map label for this gene is mmr [H]

Identifier: 41409837

GI number: 41409837

Start: 4161827

End: 4163377

Strand: Reverse

Name: mmr [H]

Synonym: MAP3739c

Alternate gene names: 41409837

Gene position: 4163377-4161827 (Counterclockwise)

Preceding gene: 41409845

Following gene: 41409836

Centisome position: 86.2

GC content: 63.64

Gene sequence:

>1551_bases
TTGTCGATAGGGGCTCAAATGCTCGACCATGCCAGATCGAACCAAACATGGACAACGGCCGTCGCCGCATTGGCATGTTT
CCTCATGACCCTCGATATCACCGTGGTCAACGTGGCGCTGCCGTCGATCCAGAAGGATCTCGGTGCCTCGCTGGAGGGAT
TGCAGTGGGTCGTCAACGCCTACGTCTTGGCCTTTGCCGCACTCTTACTGACCGTCGGCAGTGTGTCGGACCGTTTGGGG
AGAAAACGACTGTTCCTGACCGGCGTGGCCGTGTTCACCGTCGCATCGGCGTTGTGCGTGGCTTCGCGCACCGAAAGCCC
CCTGATTGCAGCCCGTGCCCTACAGGGGATCGGCGGGGCGCTGGTGTTCGGAACGTGCCTTGCGTTGATTGCCGACGCCT
ACACCGATGCTGAGGAAGAGCAACGCCGTAAGGCGGTCGGTCTAGCGATGGCCGCAGGCGCCGCCGCGGCGACGCTGGGA
CCGCTGATCGGCGGCGGGCTCGTCGAAATCGGGACGTGGCAATGGATCTTCGCCATCAACGTGCCCGTCGGCGTCGCCTT
GGCGATATGCACCGCACTCAAAGTCAGGGAACCCCACGCGCCGCACGCAGCTGACAACAGCCGGGTGGACTCGGTTGGAG
CCGTCGTTGCCATAGTGGTGTTGTTCGCCCTCAACTACGGTCTGTTGACCGGCGCCGCCAAAGGCTGGGGCCGCGGTGAT
GTGCTCGCGGCACTGGCCATCGGACTGGCGGGTGGAGTCGGGTTTGTCCTGCACCAGCTGCGGCGGGGCTCCGAGGCCAC
ACTCGACCTCACCTTGTTTCGAATCCCCACATTCCTGGCAGCTATTGTCCTGGGATTCACCGTGCGCGCCTTGAGCTTTG
GTGTCTTTCCCTTCCTCATCCTCTGGCTCGCCGGCGCGCACGGTCGCTCTGCCTTCGACATCGGACTCATCCTGTCGGCA
CTCGCCCTGCCACTGATGGTTTGCGCAGTCCTCAGCACGTCGGTTGCCCGCGCTGTCGGAGTGCGCGCGACCATGTCGAT
CGCCATGGTGATAACAGCCGCGGGACTTTTCCTTGCCACGCTGATCAGGGGAGACGGGTCGTGGACGACGATCCTGCCGG
CTCTTGCCGTGCTAGGGGTTGGTAACGGCGTCGCGATGCCCCACCTGATGAACCTTGCGGTCGATGTCGTGCCCTCCAAC
AAGGCCGGCATGGCGACCGGTGCCGCAAACACCGCGTTTCCACTGGGGACAGCGACAGGCGTGGCCGCCTTTGGTGTCGT
GTTGTCATCGTTCGTGCATGCGAAAGTCGCTGCTTCAGGGGTTATCCCGGTGCACAGTGCAGATTCCGTAGCGTCCGCCA
TCGTTGCGGGGGTGTTGAGGTTTCCCACCCAGGCAATGACCGCGTTCGCGACCTCTGCGTTCACCGATGCGCTTCGCCTG
ATCTTCGGAATTGCAGGATGCGCCGCCCTGGTCGCGGCGGGGTTGTCGGGCGCGCTCATCACACATCGTCCACGTGTGGC
CGCTGAAAGCCCGGAGTCGGTGACCGAATGA

Upstream 100 bases:

>100_bases
CGCAGGGAAGCCTGCCGATCTTGCGTTTAGCCGAGCAGGACGCGGTCCCCCCATGTGGTGACGCATGAGCTAGGATGCAC
CTTACTGAAAACGATTTTCA

Downstream 100 bases:

>100_bases
GCGTGACACCTGGCGCCGATCCGTACGCCCTGTCGGCGGAGTTCTACGAGGTGATGGCGATCCCACATTGGGATATGAAG
CGCCAAGTGCTGGTATCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: MMR peptide [H]

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MSIGAQMLDHARSNQTWTTAVAALACFLMTLDITVVNVALPSIQKDLGASLEGLQWVVNAYVLAFAALLLTVGSVSDRLG
RKRLFLTGVAVFTVASALCVASRTESPLIAARALQGIGGALVFGTCLALIADAYTDAEEEQRRKAVGLAMAAGAAAATLG
PLIGGGLVEIGTWQWIFAINVPVGVALAICTALKVREPHAPHAADNSRVDSVGAVVAIVVLFALNYGLLTGAAKGWGRGD
VLAALAIGLAGGVGFVLHQLRRGSEATLDLTLFRIPTFLAAIVLGFTVRALSFGVFPFLILWLAGAHGRSAFDIGLILSA
LALPLMVCAVLSTSVARAVGVRATMSIAMVITAAGLFLATLIRGDGSWTTILPALAVLGVGNGVAMPHLMNLAVDVVPSN
KAGMATGAANTAFPLGTATGVAAFGVVLSSFVHAKVAASGVIPVHSADSVASAIVAGVLRFPTQAMTAFATSAFTDALRL
IFGIAGCAALVAAGLSGALITHRPRVAAESPESVTE

Sequences:

>Translated_516_residues
MSIGAQMLDHARSNQTWTTAVAALACFLMTLDITVVNVALPSIQKDLGASLEGLQWVVNAYVLAFAALLLTVGSVSDRLG
RKRLFLTGVAVFTVASALCVASRTESPLIAARALQGIGGALVFGTCLALIADAYTDAEEEQRRKAVGLAMAAGAAAATLG
PLIGGGLVEIGTWQWIFAINVPVGVALAICTALKVREPHAPHAADNSRVDSVGAVVAIVVLFALNYGLLTGAAKGWGRGD
VLAALAIGLAGGVGFVLHQLRRGSEATLDLTLFRIPTFLAAIVLGFTVRALSFGVFPFLILWLAGAHGRSAFDIGLILSA
LALPLMVCAVLSTSVARAVGVRATMSIAMVITAAGLFLATLIRGDGSWTTILPALAVLGVGNGVAMPHLMNLAVDVVPSN
KAGMATGAANTAFPLGTATGVAAFGVVLSSFVHAKVAASGVIPVHSADSVASAIVAGVLRFPTQAMTAFATSAFTDALRL
IFGIAGCAALVAAGLSGALITHRPRVAAESPESVTE
>Mature_515_residues
SIGAQMLDHARSNQTWTTAVAALACFLMTLDITVVNVALPSIQKDLGASLEGLQWVVNAYVLAFAALLLTVGSVSDRLGR
KRLFLTGVAVFTVASALCVASRTESPLIAARALQGIGGALVFGTCLALIADAYTDAEEEQRRKAVGLAMAAGAAAATLGP
LIGGGLVEIGTWQWIFAINVPVGVALAICTALKVREPHAPHAADNSRVDSVGAVVAIVVLFALNYGLLTGAAKGWGRGDV
LAALAIGLAGGVGFVLHQLRRGSEATLDLTLFRIPTFLAAIVLGFTVRALSFGVFPFLILWLAGAHGRSAFDIGLILSAL
ALPLMVCAVLSTSVARAVGVRATMSIAMVITAAGLFLATLIRGDGSWTTILPALAVLGVGNGVAMPHLMNLAVDVVPSNK
AGMATGAANTAFPLGTATGVAAFGVVLSSFVHAKVAASGVIPVHSADSVASAIVAGVLRFPTQAMTAFATSAFTDALRLI
FGIAGCAALVAAGLSGALITHRPRVAAESPESVTE

Specific function: Resistance to the epoxide antibiotic methylenomycin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=408, Percent_Identity=30.8823529411765, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1790195, Length=385, Percent_Identity=31.1688311688312, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788392, Length=428, Percent_Identity=30.8411214953271, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1789042, Length=294, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788710, Length=271, Percent_Identity=29.520295202952, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790146, Length=183, Percent_Identity=31.6939890710383, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6321663, Length=153, Percent_Identity=28.7581699346405, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325455, Length=149, Percent_Identity=32.2147651006711, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=161, Percent_Identity=27.9503105590062, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324954, Length=394, Percent_Identity=23.3502538071066, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52374; Mature: 52243

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGAQMLDHARSNQTWTTAVAALACFLMTLDITVVNVALPSIQKDLGASLEGLQWVVNA
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YVLAFAALLLTVGSVSDRLGRKRLFLTGVAVFTVASALCVASRTESPLIAARALQGIGGA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
LVFGTCLALIADAYTDAEEEQRRKAVGLAMAAGAAAATLGPLIGGGLVEIGTWQWIFAIN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEEEC
VPVGVALAICTALKVREPHAPHAADNSRVDSVGAVVAIVVLFALNYGLLTGAAKGWGRGD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VLAALAIGLAGGVGFVLHQLRRGSEATLDLTLFRIPTFLAAIVLGFTVRALSFGVFPFLI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWLAGAHGRSAFDIGLILSALALPLMVCAVLSTSVARAVGVRATMSIAMVITAAGLFLAT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRGDGSWTTILPALAVLGVGNGVAMPHLMNLAVDVVPSNKAGMATGAANTAFPLGTATG
HHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHH
VAAFGVVLSSFVHAKVAASGVIPVHSADSVASAIVAGVLRFPTQAMTAFATSAFTDALRL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IFGIAGCAALVAAGLSGALITHRPRVAAESPESVTE
HHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIGAQMLDHARSNQTWTTAVAALACFLMTLDITVVNVALPSIQKDLGASLEGLQWVVNA
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YVLAFAALLLTVGSVSDRLGRKRLFLTGVAVFTVASALCVASRTESPLIAARALQGIGGA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
LVFGTCLALIADAYTDAEEEQRRKAVGLAMAAGAAAATLGPLIGGGLVEIGTWQWIFAIN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEEEC
VPVGVALAICTALKVREPHAPHAADNSRVDSVGAVVAIVVLFALNYGLLTGAAKGWGRGD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VLAALAIGLAGGVGFVLHQLRRGSEATLDLTLFRIPTFLAAIVLGFTVRALSFGVFPFLI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWLAGAHGRSAFDIGLILSALALPLMVCAVLSTSVARAVGVRATMSIAMVITAAGLFLAT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRGDGSWTTILPALAVLGVGNGVAMPHLMNLAVDVVPSNKAGMATGAANTAFPLGTATG
HHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHH
VAAFGVVLSSFVHAKVAASGVIPVHSADSVASAIVAGVLRFPTQAMTAFATSAFTDALRL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IFGIAGCAALVAAGLSGALITHRPRVAAESPESVTE
HHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379177; 9384377 [H]