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The map label for this gene is 41408538

Identifier: 41408538

GI number: 41408538

Start: 2739102

End: 2740736

Strand: Direct

Name: 41408538

Synonym: MAP2440

Alternate gene names: NA

Gene position: 2739102-2740736 (Clockwise)

Preceding gene: 41408535

Following gene: 41408540

Centisome position: 56.71

GC content: 70.21

Gene sequence:

>1635_bases
ATGTCGGCCACGCAGAGCACGGCACAACGCATCGGCCGGGTGCTCGAAAAGATCACCCGGCAAAGCGGCCGCCTGCCGGA
GACCCCCGCCTACGGCTCCCTGCTGCTGGGGCGGGTCACCGAGAGCCAGCACCGGCGGCGGATCCGCATCCAGATCATCA
TGACCGTGATGGTGCTGGGCGCCAACCTGATCGGCATCGGGGCCGCGCTGATTCTGGTGATCGTCGCCATTCCGGCGCCG
AGCGTGTTCAACGACGCGCCGGCATGGATCACCTTCGGGGTCGGGCCGGCCTATGTGGCGTCGGCGTTGGCGGTGGGCAC
CTACTGGATCACCCGGCGGACCGTGCTGGCGCTGCGCTGGGCCATCGAGGAGCGCAAGCCCACCCCCACCGACGAACGCA
ACACCTTCCTGGCCCCGTGGCGAATCGCGCTGGTGGATCTGGTGTTGTGGGGCGCCGGGACGCTGTTGCTGACCGTCCTC
TACGGCCTGGTCGACACCATGTTCATCCCGCGGTTCCTGTTCGGGGTGAGCTTCTGTGGTGTCCTGGTGGCCACCGCGTG
CTACCTGCTCGCCGAGTTCGCGCTGCGCCCGGTGGCTGCTCAGGCCCTCGAGGCGGGACCGCCGCCCCGGCGACTGACCG
CGGGCATCATGGGCCGGACCATGACGGTGTGGTTCCTCGGCTCGGGCGTGCCCGTCATCGGCATCGCCCTGTTGGCGCTG
TTCGAGATATGGCTGCGGAACCTGACCGAGACCGAGTTCGCCGTCGGCGTGCTGATCGTGTCGACGGCGGCGCTGATCTT
CGGCTGCCTGCTGATGTGGATCCTGGCCTGGCTCACCGCGACGCCCGTGCGCGTGGTGCGTGCCGCCCTGAAACGCGTGG
AGCGCGGCGACCTGCGTGGCGACCTGGTGGTGTTCGACGGCACCGAACTCGGTGAGCTGCAACGGGGATTCAACGCGATG
GTGGACGGCCTGCGGGAGCGCGAGCGGGTGCGCGACCTGTTCGGCCGGCACGTCGGTCGCGAGGTGGCGCTGGCCGCCGA
GCGGGAACGGCCGAAGCTGGGCGGCGAAGAACGCCACGTCGCCGTCGTGTTCATCGACATCGTCGGCTCCACCCAACTGG
TCACCCGCCGGCCGCCGGCCGAGGTGGTATCGGTGCTCAACCAGTTCTTCGGCATCGTCGTCGAGGAGGTGGACCGGCAC
TGCGGCTTGGTCAACAAGTTCGAGGGTGACGCGACGCTGGCCATCTTCGGGGCGCCGAATCATCTTGACTGCCCGGAGGA
TGCGGCCCTGACGGCCGCGCGCGCCATCGCCGACCGGCTGGCCAACGAGATGCCGCAGTGTCGCGCCGGCATCGGCGTGG
CGGCCGGGCAGGTCGTCGCCGGCAACGTCGGCGCCCGGGAACGCTTCGAGTACACCGTCATCGGTGAACCGGTCAACGAG
GCGGCCCGGCTGTGCGAGCTCGCCAAGTCGCACTCCAGCCGCCTGCTCGCGACGGGCGACGCCATCGAAGGCGCGAGCGA
AAAAGAGCGGGCCCGTTGGTCTTTGGGCGACACCGTGACCCTGCGCGGCCACGAGCGTCCCACCCGGCTGGCCTCGCCCG
CCGGCGCCGCCGACCGGCCGGCCGGAACGGATTGA

Upstream 100 bases:

>100_bases
GCGCGGTGAGCCGGCCGACGTAATCCACGGTGCACTGGGCGATCACTAGACGCACCCGACTCACCTTAGAGCGTGGCCGA
CAAATTAGGCTGACGCCACC

Downstream 100 bases:

>100_bases
TTTTCGGAAGAAATGGGTAGAGGGACAACGACTCTAACCCCTCGAGAGATTGGTTTCGACGTGACCGGTAGCCGAAGTGC
CCGCCGTATTTCCGTCGCCG

Product: hypothetical protein

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSATQSTAQRIGRVLEKITRQSGRLPETPAYGSLLLGRVTESQHRRRIRIQIIMTVMVLGANLIGIGAALILVIVAIPAP
SVFNDAPAWITFGVGPAYVASALAVGTYWITRRTVLALRWAIEERKPTPTDERNTFLAPWRIALVDLVLWGAGTLLLTVL
YGLVDTMFIPRFLFGVSFCGVLVATACYLLAEFALRPVAAQALEAGPPPRRLTAGIMGRTMTVWFLGSGVPVIGIALLAL
FEIWLRNLTETEFAVGVLIVSTAALIFGCLLMWILAWLTATPVRVVRAALKRVERGDLRGDLVVFDGTELGELQRGFNAM
VDGLRERERVRDLFGRHVGREVALAAERERPKLGGEERHVAVVFIDIVGSTQLVTRRPPAEVVSVLNQFFGIVVEEVDRH
CGLVNKFEGDATLAIFGAPNHLDCPEDAALTAARAIADRLANEMPQCRAGIGVAAGQVVAGNVGARERFEYTVIGEPVNE
AARLCELAKSHSSRLLATGDAIEGASEKERARWSLGDTVTLRGHERPTRLASPAGAADRPAGTD

Sequences:

>Translated_544_residues
MSATQSTAQRIGRVLEKITRQSGRLPETPAYGSLLLGRVTESQHRRRIRIQIIMTVMVLGANLIGIGAALILVIVAIPAP
SVFNDAPAWITFGVGPAYVASALAVGTYWITRRTVLALRWAIEERKPTPTDERNTFLAPWRIALVDLVLWGAGTLLLTVL
YGLVDTMFIPRFLFGVSFCGVLVATACYLLAEFALRPVAAQALEAGPPPRRLTAGIMGRTMTVWFLGSGVPVIGIALLAL
FEIWLRNLTETEFAVGVLIVSTAALIFGCLLMWILAWLTATPVRVVRAALKRVERGDLRGDLVVFDGTELGELQRGFNAM
VDGLRERERVRDLFGRHVGREVALAAERERPKLGGEERHVAVVFIDIVGSTQLVTRRPPAEVVSVLNQFFGIVVEEVDRH
CGLVNKFEGDATLAIFGAPNHLDCPEDAALTAARAIADRLANEMPQCRAGIGVAAGQVVAGNVGARERFEYTVIGEPVNE
AARLCELAKSHSSRLLATGDAIEGASEKERARWSLGDTVTLRGHERPTRLASPAGAADRPAGTD
>Mature_543_residues
SATQSTAQRIGRVLEKITRQSGRLPETPAYGSLLLGRVTESQHRRRIRIQIIMTVMVLGANLIGIGAALILVIVAIPAPS
VFNDAPAWITFGVGPAYVASALAVGTYWITRRTVLALRWAIEERKPTPTDERNTFLAPWRIALVDLVLWGAGTLLLTVLY
GLVDTMFIPRFLFGVSFCGVLVATACYLLAEFALRPVAAQALEAGPPPRRLTAGIMGRTMTVWFLGSGVPVIGIALLALF
EIWLRNLTETEFAVGVLIVSTAALIFGCLLMWILAWLTATPVRVVRAALKRVERGDLRGDLVVFDGTELGELQRGFNAMV
DGLRERERVRDLFGRHVGREVALAAERERPKLGGEERHVAVVFIDIVGSTQLVTRRPPAEVVSVLNQFFGIVVEEVDRHC
GLVNKFEGDATLAIFGAPNHLDCPEDAALTAARAIADRLANEMPQCRAGIGVAAGQVVAGNVGARERFEYTVIGEPVNEA
ARLCELAKSHSSRLLATGDAIEGASEKERARWSLGDTVTLRGHERPTRLASPAGAADRPAGTD

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: 4.6.1.1

Molecular weight: Translated: 58882; Mature: 58751

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATQSTAQRIGRVLEKITRQSGRLPETPAYGSLLLGRVTESQHRRRIRIQIIMTVMVLG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANLIGIGAALILVIVAIPAPSVFNDAPAWITFGVGPAYVASALAVGTYWITRRTVLALRW
CHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIEERKPTPTDERNTFLAPWRIALVDLVLWGAGTLLLTVLYGLVDTMFIPRFLFGVSFCG
HHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVATACYLLAEFALRPVAAQALEAGPPPRRLTAGIMGRTMTVWFLGSGVPVIGIALLAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHH
FEIWLRNLTETEFAVGVLIVSTAALIFGCLLMWILAWLTATPVRVVRAALKRVERGDLRG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
DLVVFDGTELGELQRGFNAMVDGLRERERVRDLFGRHVGREVALAAERERPKLGGEERHV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCEE
AVVFIDIVGSTQLVTRRPPAEVVSVLNQFFGIVVEEVDRHCGLVNKFEGDATLAIFGAPN
EEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCC
HLDCPEDAALTAARAIADRLANEMPQCRAGIGVAAGQVVAGNVGARERFEYTVIGEPVNE
CCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCEEECCCCCCCCEEEEEECCCHHH
AARLCELAKSHSSRLLATGDAIEGASEKERARWSLGDTVTLRGHERPTRLASPAGAADRP
HHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCEEEECCCCCCCHHCCCCCCCCCC
AGTD
CCCC
>Mature Secondary Structure 
SATQSTAQRIGRVLEKITRQSGRLPETPAYGSLLLGRVTESQHRRRIRIQIIMTVMVLG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANLIGIGAALILVIVAIPAPSVFNDAPAWITFGVGPAYVASALAVGTYWITRRTVLALRW
CHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIEERKPTPTDERNTFLAPWRIALVDLVLWGAGTLLLTVLYGLVDTMFIPRFLFGVSFCG
HHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVATACYLLAEFALRPVAAQALEAGPPPRRLTAGIMGRTMTVWFLGSGVPVIGIALLAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHH
FEIWLRNLTETEFAVGVLIVSTAALIFGCLLMWILAWLTATPVRVVRAALKRVERGDLRG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
DLVVFDGTELGELQRGFNAMVDGLRERERVRDLFGRHVGREVALAAERERPKLGGEERHV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCEE
AVVFIDIVGSTQLVTRRPPAEVVSVLNQFFGIVVEEVDRHCGLVNKFEGDATLAIFGAPN
EEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCC
HLDCPEDAALTAARAIADRLANEMPQCRAGIGVAAGQVVAGNVGARERFEYTVIGEPVNE
CCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCEEECCCCCCCCEEEEEECCCHHH
AARLCELAKSHSSRLLATGDAIEGASEKERARWSLGDTVTLRGHERPTRLASPAGAADRP
HHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCEEEECCCCCCCHHCCCCCCCCCC
AGTD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]