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The map label for this gene is yybE [H]

Identifier: 41408540

GI number: 41408540

Start: 2742529

End: 2743413

Strand: Direct

Name: yybE [H]

Synonym: MAP2442

Alternate gene names: 41408540

Gene position: 2742529-2743413 (Clockwise)

Preceding gene: 41408538

Following gene: 41408541

Centisome position: 56.78

GC content: 69.04

Gene sequence:

>885_bases
ATGGCAGTGGGTGACTACGAGTGGTTCATCACACTCGCCGAGCTGCAGCACGTCACCGCGGCGGCCGAGCAGCTGCACGT
CGCACAGCCGACGTTGACCCGGATGCTGGCGCGCCTGGAACAGCGACTCGGCGTGGCGCTGTTCGATCGTCACGGCCGGC
GACTGTCCCTCAACACCTACGGCCGCATCTTCTACGAACACGCGCGCCGGGCGCAGTTGGAGCTGGATTCGGCACGGCGT
GCGATAGCGGATCTGGCGGATCCCGCCGTCGGCGAGATCCGGTTGGCCTACCTGAGTTCATTCGGATCAACCGTGGTGCC
GCGGTTGATCGCCCGGTTCAAGGAGTCGTCTCCGCGGGTGACCTTCACGCTGGAGAAAGGCGCCGCCGAATCGATCGCCG
ATCGCGTGCGGTCCGGCGGCGTGGACATCGGGGTGGTATCCCCGCGACCGGTCGAGCGAACCCTGGCCTGGCGCAGCCTG
TTTCGCCAGCGCCTCGGTGTCGCGGTGCCCGATGGTCATCGATTCGCCCGCGGTGCCGCGGTGTCCATGGTGGACCTGGC
CGACGAGCCCTTCGTGACGATGCACCCCGGTTTCGGGATGCGACGGCTCCTCGACGAGCTTTGCGCCGCAGCCCAATTCC
GGCCTCGGGTCGCCCTGCAAGCGCCGAATCTCACGACCGCGGCCAGCCTAGTCGCCGCGGGGCTGGGCATCAGCCTGGTC
CCGATCGACGGCAGCAGCTATCCGTCGGGAGTATCCGTCAAGCCGCTGGCCGACGCGGATGCCTACCGCGATGTCGGCAT
GATCTGGGATTCCGGCCGGCCGTTGCCGCGTTCGGCGCGCGACTTCATCGCGGCCGCCGCGGCCGTCGGGCGCGGCGGCT
GGTAG

Upstream 100 bases:

>100_bases
CGTGGGGCATGACCACCATGCTTCGGGCCGGCACCGCCCGACAGAAATGAATTTTCGCCCGCCCTATGATGCGTTCAGCG
CATAAGCAGAGGTGGGCGGG

Downstream 100 bases:

>100_bases
CCGGCCGCCGATCCCGCTCCACGCCCGGCGACGACGATGTCGCTTTTCCGCTAGTTTTGTCGGCGGGCGGGTGTAAGTCT
TGAGGCGTGCACGACGATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRLGVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARR
AIADLADPAVGEIRLAYLSSFGSTVVPRLIARFKESSPRVTFTLEKGAAESIADRVRSGGVDIGVVSPRPVERTLAWRSL
FRQRLGVAVPDGHRFARGAAVSMVDLADEPFVTMHPGFGMRRLLDELCAAAQFRPRVALQAPNLTTAASLVAAGLGISLV
PIDGSSYPSGVSVKPLADADAYRDVGMIWDSGRPLPRSARDFIAAAAAVGRGGW

Sequences:

>Translated_294_residues
MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRLGVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARR
AIADLADPAVGEIRLAYLSSFGSTVVPRLIARFKESSPRVTFTLEKGAAESIADRVRSGGVDIGVVSPRPVERTLAWRSL
FRQRLGVAVPDGHRFARGAAVSMVDLADEPFVTMHPGFGMRRLLDELCAAAQFRPRVALQAPNLTTAASLVAAGLGISLV
PIDGSSYPSGVSVKPLADADAYRDVGMIWDSGRPLPRSARDFIAAAAAVGRGGW
>Mature_293_residues
AVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRLGVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARRA
IADLADPAVGEIRLAYLSSFGSTVVPRLIARFKESSPRVTFTLEKGAAESIADRVRSGGVDIGVVSPRPVERTLAWRSLF
RQRLGVAVPDGHRFARGAAVSMVDLADEPFVTMHPGFGMRRLLDELCAAAQFRPRVALQAPNLTTAASLVAAGLGISLVP
IDGSSYPSGVSVKPLADADAYRDVGMIWDSGRPLPRSARDFIAAAAAVGRGGW

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=251, Percent_Identity=30.6772908366534, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=25.6055363321799, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=24.8299319727891, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787879, Length=280, Percent_Identity=26.7857142857143, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=27.2, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789204, Length=282, Percent_Identity=27.3049645390071, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI145693105, Length=279, Percent_Identity=24.7311827956989, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367136, Length=265, Percent_Identity=28.6792452830189, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788481, Length=222, Percent_Identity=29.2792792792793, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788296, Length=230, Percent_Identity=28.2608695652174, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787601, Length=255, Percent_Identity=24.7058823529412, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787806, Length=282, Percent_Identity=25.886524822695, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082132, Length=248, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788297, Length=236, Percent_Identity=20.3389830508475, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=24.6913580246914, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790208, Length=247, Percent_Identity=25.9109311740891, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31885; Mature: 31754

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRLGVALFDRHGRRLSLNTY
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCEEEEHHH
GRIFYEHARRAQLELDSARRAIADLADPAVGEIRLAYLSSFGSTVVPRLIARFKESSPRV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCE
TFTLEKGAAESIADRVRSGGVDIGVVSPRPVERTLAWRSLFRQRLGVAVPDGHRFARGAA
EEEECCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCHH
VSMVDLADEPFVTMHPGFGMRRLLDELCAAAQFRPRVALQAPNLTTAASLVAAGLGISLV
EEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCEEEE
PIDGSSYPSGVSVKPLADADAYRDVGMIWDSGRPLPRSARDFIAAAAAVGRGGW
EECCCCCCCCCCCCCCCCCHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRLGVALFDRHGRRLSLNTY
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCEEEEHHH
GRIFYEHARRAQLELDSARRAIADLADPAVGEIRLAYLSSFGSTVVPRLIARFKESSPRV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCE
TFTLEKGAAESIADRVRSGGVDIGVVSPRPVERTLAWRSLFRQRLGVAVPDGHRFARGAA
EEEECCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCHH
VSMVDLADEPFVTMHPGFGMRRLLDELCAAAQFRPRVALQAPNLTTAASLVAAGLGISLV
EEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCEEEE
PIDGSSYPSGVSVKPLADADAYRDVGMIWDSGRPLPRSARDFIAAAAAVGRGGW
EECCCCCCCCCCCCCCCCCHHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]