Click here to switch to the map view.

The map label for this gene is echA10

Identifier: 41408495

GI number: 41408495

Start: 2692629

End: 2693489

Strand: Direct

Name: echA10

Synonym: MAP2397

Alternate gene names: 41408495

Gene position: 2692629-2693489 (Clockwise)

Preceding gene: 41408492

Following gene: 41408496

Centisome position: 55.75

GC content: 70.73

Gene sequence:

>861_bases
ATGGGTAACCGTATCGGTGAAGAAAGGCCGGATTCGACGGTGAGTCAGGGGGCCGACGCGGCCGCAGCCGAGGGTTCGGT
GGCGGTGCACCGCCAGGGTGCGGTGCTGCGCCTCACGCTCGATCGCCCGTCGCGGCGTAATGCGTTGACGCAGTTGATGA
TCGCCACACTGGTCGATGCGCTGACCGCCGCGGCCTCCGACGATTCGCTGCGCGCCGTGCACATCGTCGGCGCCGGGGAC
GACTTCTGCGCCGGCGCCGACTGGGTGGCCGTCAACGATCCGGGCGGGCCCCGCCCGCGCGCCGGTGATCTGGTGCGCCG
CATCCCCCACGCCGCGCACCGGGTGATCGAGCTCGTCGCCGGCATCCAGCTGCCGGTGGTGTGCAGTGTCCGCGGCTGGG
CGGTGGGGTTCGGCTGCAATCTGGCGCTGGCCGCCGACTTCACCGTCGCCGCCGCCGATGCGGTGTTCTGGGAGCCTTTC
GTCGAGCGAGGATTCAGCCCCGACTCGGGATCCACCTGGTTGCTGGCCCGGCTGGTCGGCCTGGCGCGGGCGCGGCGGAT
GCTGCTGCTGGGCGAGAAGGTCGGCGGACGCGACGCGGCCGACTGGGGGTTGATCCACCGGGCGGTCGGCGGCGCCGAAC
TCGACGACGCCGCCGAGGAGTTGGTGGGCCGGCTGGCCGCCGGACCGACCGCCGCGCTCGGCCTGGCCAAGCAGGCGCTG
AGCTTCGGTCAGCACGCAACGCTGAGCCAGTCGCTGACCCAGGAGTTGTTCAATCTGGAATTATCTTGCCGAACAAGTGA
TTTCAAGGAAGGCCTGGAGGCGTTCCGGCAGCGACGGGACCCGGATTTCCGTGGCCGCTGA

Upstream 100 bases:

>100_bases
GTGCGTCGCCGCCCGCGCGGGTCGCGCTGTCACCGGGGTTGTTTCGCAGGCAGCGTATCCTTGCTAACTTATACAGCGTA
TCAATCGTATTGCCTACTGT

Downstream 100 bases:

>100_bases
CTACAGGCGCCGGGGCGTCGAGCGTGGGCGCCATGCACGAAAAGCGGCGCCCACCCGTATATACGGCCCACGCTCGGTGG
CGCCGGGATACGAAGGGATG

Product: EchA10

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MGNRIGEERPDSTVSQGADAAAAEGSVAVHRQGAVLRLTLDRPSRRNALTQLMIATLVDALTAAASDDSLRAVHIVGAGD
DFCAGADWVAVNDPGGPRPRAGDLVRRIPHAAHRVIELVAGIQLPVVCSVRGWAVGFGCNLALAADFTVAAADAVFWEPF
VERGFSPDSGSTWLLARLVGLARARRMLLLGEKVGGRDAADWGLIHRAVGGAELDDAAEELVGRLAAGPTAALGLAKQAL
SFGQHATLSQSLTQELFNLELSCRTSDFKEGLEAFRQRRDPDFRGR

Sequences:

>Translated_286_residues
MGNRIGEERPDSTVSQGADAAAAEGSVAVHRQGAVLRLTLDRPSRRNALTQLMIATLVDALTAAASDDSLRAVHIVGAGD
DFCAGADWVAVNDPGGPRPRAGDLVRRIPHAAHRVIELVAGIQLPVVCSVRGWAVGFGCNLALAADFTVAAADAVFWEPF
VERGFSPDSGSTWLLARLVGLARARRMLLLGEKVGGRDAADWGLIHRAVGGAELDDAAEELVGRLAAGPTAALGLAKQAL
SFGQHATLSQSLTQELFNLELSCRTSDFKEGLEAFRQRRDPDFRGR
>Mature_285_residues
GNRIGEERPDSTVSQGADAAAAEGSVAVHRQGAVLRLTLDRPSRRNALTQLMIATLVDALTAAASDDSLRAVHIVGAGDD
FCAGADWVAVNDPGGPRPRAGDLVRRIPHAAHRVIELVAGIQLPVVCSVRGWAVGFGCNLALAADFTVAAADAVFWEPFV
ERGFSPDSGSTWLLARLVGLARARRMLLLGEKVGGRDAADWGLIHRAVGGAELDDAAEELVGRLAAGPTAALGLAKQALS
FGQHATLSQSLTQELFNLELSCRTSDFKEGLEAFRQRRDPDFRGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=256, Percent_Identity=27.34375, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=25.9090909090909, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=25.9090909090909, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=25.9090909090909, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI25453481, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI51538573, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4757966, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI51538581, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4757968, Length=193, Percent_Identity=30.0518134715026, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI49355787, Length=193, Percent_Identity=30.0518134715026, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=27.2, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=26.6917293233083, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI221136756, Length=259, Percent_Identity=23.5521235521236, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI221136753, Length=259, Percent_Identity=23.5521235521236, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI221307494, Length=183, Percent_Identity=27.3224043715847, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI37594469, Length=210, Percent_Identity=28.0952380952381, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI37594471, Length=210, Percent_Identity=28.0952380952381, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4502327, Length=257, Percent_Identity=29.1828793774319, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI157694516, Length=235, Percent_Identity=23.4042553191489, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI213417737, Length=235, Percent_Identity=23.4042553191489, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI68989263, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=38.6973180076628, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=35.6589147286822, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=31.3653136531365, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=30.46875, Blast_Score=94, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17535521, Length=215, Percent_Identity=27.906976744186, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=260, Percent_Identity=27.6923076923077, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=27.2373540856031, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=231, Percent_Identity=25.5411255411255, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=221, Percent_Identity=26.2443438914027, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=228, Percent_Identity=27.1929824561404, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25144157, Length=211, Percent_Identity=30.3317535545024, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25144160, Length=211, Percent_Identity=30.3317535545024, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=242, Percent_Identity=25.6198347107438, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=232, Percent_Identity=25, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129971, Length=246, Percent_Identity=29.2682926829268, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24653477, Length=246, Percent_Identity=29.2682926829268, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21357171, Length=275, Percent_Identity=29.0909090909091, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24653139, Length=261, Percent_Identity=28.735632183908, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19922422, Length=264, Percent_Identity=26.8939393939394, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24654903, Length=253, Percent_Identity=21.7391304347826, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 30249; Mature: 30117

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRIGEERPDSTVSQGADAAAAEGSVAVHRQGAVLRLTLDRPSRRNALTQLMIATLVDA
CCCCCCCCCCCCHHHCCCCCHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHH
LTAAASDDSLRAVHIVGAGDDFCAGADWVAVNDPGGPRPRAGDLVRRIPHAAHRVIELVA
HHHHCCCCCEEEEEEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GIQLPVVCSVRGWAVGFGCNLALAADFTVAAADAVFWEPFVERGFSPDSGSTWLLARLVG
CCCCCEEEECCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LARARRMLLLGEKVGGRDAADWGLIHRAVGGAELDDAAEELVGRLAAGPTAALGLAKQAL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
SFGQHATLSQSLTQELFNLELSCRTSDFKEGLEAFRQRRDPDFRGR
HCCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GNRIGEERPDSTVSQGADAAAAEGSVAVHRQGAVLRLTLDRPSRRNALTQLMIATLVDA
CCCCCCCCCCCHHHCCCCCHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHH
LTAAASDDSLRAVHIVGAGDDFCAGADWVAVNDPGGPRPRAGDLVRRIPHAAHRVIELVA
HHHHCCCCCEEEEEEEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GIQLPVVCSVRGWAVGFGCNLALAADFTVAAADAVFWEPFVERGFSPDSGSTWLLARLVG
CCCCCEEEECCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LARARRMLLLGEKVGGRDAADWGLIHRAVGGAELDDAAEELVGRLAAGPTAALGLAKQAL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
SFGQHATLSQSLTQELFNLELSCRTSDFKEGLEAFRQRRDPDFRGR
HCCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]