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The map label for this gene is frc [H]

Identifier: 41408481

GI number: 41408481

Start: 2678153

End: 2679379

Strand: Direct

Name: frc [H]

Synonym: MAP2383

Alternate gene names: 41408481

Gene position: 2678153-2679379 (Clockwise)

Preceding gene: 41408480

Following gene: 41408482

Centisome position: 55.45

GC content: 66.42

Gene sequence:

>1227_bases
ATGGTGAAGGTAATGCAGGGCTTTCGGGTCCTCGAGGTTGCGCAGTTCACGTTCGTCCCGGCCGCCGGCGCGATCCTGGC
GGACTGGGGTGCCGACGTCATCAAGGTCGAACACCCGGTGCGCGGCGACACCCAGCGCGGCTTCGTGAACATGGGTGGCA
TCCAGGTTGTTCCAGAGCGTCACCCGCTGATGGAGCACCCCAACCGGGGCAAGCGCAGCGTCGGGGTCGACGTGTCCACG
CCGGGCGGCCAGGAGGTGATCTACGAACTGGCCAAGACCTCCGATGTGTTCCTCACCAATTACATGCCCGCGCAGCGTCG
CAAGCACAAGTTCGACGTGGAGCACATCCGGGCGGTCAACCCGAACATCGTGTACGCCCGCGGTTCGGCGTACGGGGACA
AGGGCGCCGAGCGTGACGTCGGCGGTTACGACGGGACGGCGTTCTGGACTTGCAGCGGGATCGGCTACGCGCTGACGCCG
GAGGAGTTGGGCGGCGCACTGGGACAAGGCATTCCCGCATTCGGCGATTCCATCGGCGGCATGTTCATCGCCGGCGGGAT
CTCGGCGGCGTTGCTGCACCGTGAACGCACCGGCGAGGCCGTCGAGCTCGACGTGTCGCTGCTGAGCACGGCATGGTGGG
CGGCGGGCGCCAGCGTGACGCAGGGCATGGAGACCGGCGAAGTGATGCGCACCCCGATGCCGGGTGCCGGGACGCCGTCG
GTGAATCCGTTCATGGGCAACTATGAGACCTCCGACGGCGGCACCATCAACCTGTGCATCATCAGCCCGACCGGACTGAT
CCGCGACACGTTCGAGCACCTCGGCATCCCCGAGGCGGCCGACGATCCCCGGTTCTGTGATGTGCTGCCGCTGATCCAGA
ACGCCGACGCGGCCGCCGAGCTGATCGCAAAGGCGTTCGCCGCCAAGCCCTTTGACTATTGGCGCCAGCACCTGAAGACG
ATGAAGGGCCAGTGGGCGCCGTTCCAGAGCCTGCTCGACCTGATCGACGACGAGCAGGCCATCGCCAACGACATGATCGC
CGAGGTCGAACTCGCCGGCGGCGGAAAGCCTTTCCGCGTGGTGCGCGGCCCGGTGCAGTTCAATCACGAGCCGCTCGCGA
CGACGAGGGCACCCCAGGCCAGTGAGCACACCGAGCTGGTGCTGATGGAGTTGGGGATGGACTGGGACCGCATCGAGGAG
CTCAAGAATGCAGGAGCCATTGCGTGA

Upstream 100 bases:

>100_bases
GTCACCCTGCTCAGCGACGGCGACCCGCACATCCACGGTCAGCCGTTCCGGTCTCCGACGGCACTTCCGGTTACCTTCGA
CGCCAAGTAGGGTCCCGGGA

Downstream 100 bases:

>100_bases
GTGCGAGTCGCGCCGCAACGATGCAGAGCGAAGCGATGAGGAGGAGCGGCGCCAATGAGTGACGTCGCCATCATCGGCGT
CGGCCTGCACCCGTTCGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MVKVMQGFRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFVNMGGIQVVPERHPLMEHPNRGKRSVGVDVST
PGGQEVIYELAKTSDVFLTNYMPAQRRKHKFDVEHIRAVNPNIVYARGSAYGDKGAERDVGGYDGTAFWTCSGIGYALTP
EELGGALGQGIPAFGDSIGGMFIAGGISAALLHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGEVMRTPMPGAGTPS
VNPFMGNYETSDGGTINLCIISPTGLIRDTFEHLGIPEAADDPRFCDVLPLIQNADAAAELIAKAFAAKPFDYWRQHLKT
MKGQWAPFQSLLDLIDDEQAIANDMIAEVELAGGGKPFRVVRGPVQFNHEPLATTRAPQASEHTELVLMELGMDWDRIEE
LKNAGAIA

Sequences:

>Translated_408_residues
MVKVMQGFRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFVNMGGIQVVPERHPLMEHPNRGKRSVGVDVST
PGGQEVIYELAKTSDVFLTNYMPAQRRKHKFDVEHIRAVNPNIVYARGSAYGDKGAERDVGGYDGTAFWTCSGIGYALTP
EELGGALGQGIPAFGDSIGGMFIAGGISAALLHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGEVMRTPMPGAGTPS
VNPFMGNYETSDGGTINLCIISPTGLIRDTFEHLGIPEAADDPRFCDVLPLIQNADAAAELIAKAFAAKPFDYWRQHLKT
MKGQWAPFQSLLDLIDDEQAIANDMIAEVELAGGGKPFRVVRGPVQFNHEPLATTRAPQASEHTELVLMELGMDWDRIEE
LKNAGAIA
>Mature_408_residues
MVKVMQGFRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFVNMGGIQVVPERHPLMEHPNRGKRSVGVDVST
PGGQEVIYELAKTSDVFLTNYMPAQRRKHKFDVEHIRAVNPNIVYARGSAYGDKGAERDVGGYDGTAFWTCSGIGYALTP
EELGGALGQGIPAFGDSIGGMFIAGGISAALLHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGEVMRTPMPGAGTPS
VNPFMGNYETSDGGTINLCIISPTGLIRDTFEHLGIPEAADDPRFCDVLPLIQNADAAAELIAKAFAAKPFDYWRQHLKT
MKGQWAPFQSLLDLIDDEQAIANDMIAEVELAGGGKPFRVVRGPVQFNHEPLATTRAPQASEHTELVLMELGMDWDRIEE
LKNAGAIA

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=419, Percent_Identity=26.0143198090692, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI300863124, Length=445, Percent_Identity=26.0674157303371, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI42794625, Length=416, Percent_Identity=26.2019230769231, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI266456254, Length=416, Percent_Identity=26.2019230769231, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI300863126, Length=160, Percent_Identity=33.125, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI266458393, Length=267, Percent_Identity=28.4644194756554, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI266458397, Length=267, Percent_Identity=28.4644194756554, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87082093, Length=365, Percent_Identity=25.7534246575342, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788717, Length=211, Percent_Identity=29.8578199052133, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648431, Length=413, Percent_Identity=26.8765133171913, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24585488, Length=417, Percent_Identity=23.021582733813, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 43974; Mature: 43974

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVMQGFRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFVNMGGIQVVPER
CCCHHCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCEEECCCC
HPLMEHPNRGKRSVGVDVSTPGGQEVIYELAKTSDVFLTNYMPAQRRKHKFDVEHIRAVN
CCCCCCCCCCCCEECEEECCCCHHHHHHHHHHCCCEEEECCCCHHHHHHCCCHHHHEECC
PNIVYARGSAYGDKGAERDVGGYDGTAFWTCSGIGYALTPEELGGALGQGIPAFGDSIGG
CCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCEEECHHHHHHHHHCCCCHHCCCCCC
MFIAGGISAALLHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGEVMRTPMPGAGTPS
EEECCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHCCCCCCHHHCCCCCCCCCCC
VNPFMGNYETSDGGTINLCIISPTGLIRDTFEHLGIPEAADDPRFCDVLPLIQNADAAAE
CCCCCCCEECCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHH
LIAKAFAAKPFDYWRQHLKTMKGQWAPFQSLLDLIDDEQAIANDMIAEVELAGGGKPFRV
HHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHEEEEECCCCCCEEE
VRGPVQFNHEPLATTRAPQASEHTELVLMELGMDWDRIEELKNAGAIA
EECCHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MVKVMQGFRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQRGFVNMGGIQVVPER
CCCHHCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCEEECCCC
HPLMEHPNRGKRSVGVDVSTPGGQEVIYELAKTSDVFLTNYMPAQRRKHKFDVEHIRAVN
CCCCCCCCCCCCEECEEECCCCHHHHHHHHHHCCCEEEECCCCHHHHHHCCCHHHHEECC
PNIVYARGSAYGDKGAERDVGGYDGTAFWTCSGIGYALTPEELGGALGQGIPAFGDSIGG
CCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCEEECHHHHHHHHHCCCCHHCCCCCC
MFIAGGISAALLHRERTGEAVELDVSLLSTAWWAAGASVTQGMETGEVMRTPMPGAGTPS
EEECCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHCCCCCCHHHCCCCCCCCCCC
VNPFMGNYETSDGGTINLCIISPTGLIRDTFEHLGIPEAADDPRFCDVLPLIQNADAAAE
CCCCCCCEECCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHH
LIAKAFAAKPFDYWRQHLKTMKGQWAPFQSLLDLIDDEQAIANDMIAEVELAGGGKPFRV
HHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHEEEEECCCCCCEEE
VRGPVQFNHEPLATTRAPQASEHTELVLMELGMDWDRIEELKNAGAIA
EECCHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]