Click here to switch to the map view.

The map label for this gene is 41408482

Identifier: 41408482

GI number: 41408482

Start: 2679434

End: 2680579

Strand: Direct

Name: 41408482

Synonym: MAP2384

Alternate gene names: NA

Gene position: 2679434-2680579 (Clockwise)

Preceding gene: 41408481

Following gene: 41408489

Centisome position: 55.48

GC content: 68.59

Gene sequence:

>1146_bases
ATGAGTGACGTCGCCATCATCGGCGTCGGCCTGCACCCGTTCGGCCGCTTCGAGGGCAAGACCGCGATGGAGATGGCCGT
CGACGCCATCCAGCTCGCGGTGGCCGACGCGGGTGTCGAGTGGAAGGACATCCAGGCCGCCACCGGGGGCAGCTGGACGG
TGGCCAACCCGGACGCGATCGTCGGCATGGTGGGGCTTTCGGGCATTCCGTTCACCAACGTGTTCAATGCCTGCGCGACC
GCGGCCAGTGCCGCCAAGGCGTGCGCCGACGGAATCCGGCTCGGTGACTACGACATCGGCATCGCCATCGGCCTGGACAA
GCATCCGCGGGGTGCGTTCACCGAGGACCCGGCCCTGGTGGGGATGCCGCGCTGGTATGCCGAGAATGGGCAGTACCTCA
CCACACAGTTCTTCGGCATGAAGGCCAACCGCTACCTGCACCAGCACGGCATCTCGCAGCGGACCCTGGCCAAGGTCGCG
GCCAAGAACTTCCGCAACGGCGCCCGCAACCCGAATGCCTTCCGGCGCAAGCCGATTCCGGAGGATGAGATCCTCAACTC
GCCGATGCTGAACTACCCGCTCACCCAGTACATGTTCTGCGCGCCCGACGAGGGCGCGGCGGCGGTGGTGATGTGCCGGG
CCGACATCGCGCACCGGTACAGCGCCAAGCCCGTCTATCTGCGCGCGGTCGAGGTGCGCACCCGCCGCTACGGCGCCTAC
GAGGTGAACACCACCTTCGCCCCGGTCGACGAGGATGTGGCGCCCACCGTGTACGCGGCGCGGGCCGCGTTCGAAAAGGC
CGGTGTGGCACCGCAAGACGTCGACGTGATCCAGCTGCAGGACACCGACGCCGGGGCGGAGATCATCCACATGGCCGAGT
GCGGGTTCTGCGCCGACGGCGAGCAGGAGAAGCTGCTCGCCGACGGAGTCACCGAGATCACCGGCGCGATGCCGATCAAC
ACCGACGGCGGGCTGATCGCCAACGGCGAACCGATCGGCGCGTCCGGCCTGCGCCAAATCCACGAGCTGGTGCGGCAATT
GCGTGGCGAAGCCGGCGATCGGCAGGTGGCCGGTGAGCCGCGCGTCGGGTTCGCTCAGCTCTACGGTGCCCCGGGTACCG
CGGCGGCCACCATCCTGACCACCTGA

Upstream 100 bases:

>100_bases
CTGGGACCGCATCGAGGAGCTCAAGAATGCAGGAGCCATTGCGTGAGTGCGAGTCGCGCCGCAACGATGCAGAGCGAAGC
GATGAGGAGGAGCGGCGCCA

Downstream 100 bases:

>100_bases
CCGTCGCCGAGCGTGCACCCAGCGCGAAAAAGTGCGCGGAATTTCGCGGCCAGTGCACGTTCGGCGCGCAGGAGGCGCGG
CAGGAGGCGCGCAGGAGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSDVAIIGVGLHPFGRFEGKTAMEMAVDAIQLAVADAGVEWKDIQAATGGSWTVANPDAIVGMVGLSGIPFTNVFNACAT
AASAAKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALVGMPRWYAENGQYLTTQFFGMKANRYLHQHGISQRTLAKVA
AKNFRNGARNPNAFRRKPIPEDEILNSPMLNYPLTQYMFCAPDEGAAAVVMCRADIAHRYSAKPVYLRAVEVRTRRYGAY
EVNTTFAPVDEDVAPTVYAARAAFEKAGVAPQDVDVIQLQDTDAGAEIIHMAECGFCADGEQEKLLADGVTEITGAMPIN
TDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVAGEPRVGFAQLYGAPGTAAATILTT

Sequences:

>Translated_381_residues
MSDVAIIGVGLHPFGRFEGKTAMEMAVDAIQLAVADAGVEWKDIQAATGGSWTVANPDAIVGMVGLSGIPFTNVFNACAT
AASAAKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALVGMPRWYAENGQYLTTQFFGMKANRYLHQHGISQRTLAKVA
AKNFRNGARNPNAFRRKPIPEDEILNSPMLNYPLTQYMFCAPDEGAAAVVMCRADIAHRYSAKPVYLRAVEVRTRRYGAY
EVNTTFAPVDEDVAPTVYAARAAFEKAGVAPQDVDVIQLQDTDAGAEIIHMAECGFCADGEQEKLLADGVTEITGAMPIN
TDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVAGEPRVGFAQLYGAPGTAAATILTT
>Mature_380_residues
SDVAIIGVGLHPFGRFEGKTAMEMAVDAIQLAVADAGVEWKDIQAATGGSWTVANPDAIVGMVGLSGIPFTNVFNACATA
ASAAKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALVGMPRWYAENGQYLTTQFFGMKANRYLHQHGISQRTLAKVAA
KNFRNGARNPNAFRRKPIPEDEILNSPMLNYPLTQYMFCAPDEGAAAVVMCRADIAHRYSAKPVYLRAVEVRTRRYGAYE
VNTTFAPVDEDVAPTVYAARAAFEKAGVAPQDVDVIQLQDTDAGAEIIHMAECGFCADGEQEKLLADGVTEITGAMPINT
DGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVAGEPRVGFAQLYGAPGTAAATILTT

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=392, Percent_Identity=29.5918367346939, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI302344760, Length=331, Percent_Identity=30.5135951661631, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI302344767, Length=324, Percent_Identity=30.2469135802469, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI302344762, Length=321, Percent_Identity=28.6604361370716, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI55956775, Length=279, Percent_Identity=26.1648745519713, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17537653, Length=375, Percent_Identity=29.3333333333333, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24585051, Length=381, Percent_Identity=29.3963254593176, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI19921506, Length=383, Percent_Identity=28.9817232375979, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40534; Mature: 40403

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVAIIGVGLHPFGRFEGKTAMEMAVDAIQLAVADAGVEWKDIQAATGGSWTVANPDAI
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEEECCCCCE
VGMVGLSGIPFTNVFNACATAASAAKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCCCCCCCCCCCCCEE
GMPRWYAENGQYLTTQFFGMKANRYLHQHGISQRTLAKVAAKNFRNGARNPNAFRRKPIP
CCCHHCCCCCCEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCC
EDEILNSPMLNYPLTQYMFCAPDEGAAAVVMCRADIAHRYSAKPVYLRAVEVRTRRYGAY
HHHHHCCCCCCCCHHHEEEECCCCCCEEEEEEEHHHHHHCCCCCEEEEEEEEHHHHCCEE
EVNTTFAPVDEDVAPTVYAARAAFEKAGVAPQDVDVIQLQDTDAGAEIIHMAECGFCADG
EECCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCC
EQEKLLADGVTEITGAMPINTDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVAGEP
CHHHHHHCCHHHHHCCCEECCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
RVGFAQLYGAPGTAAATILTT
CCCHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure 
SDVAIIGVGLHPFGRFEGKTAMEMAVDAIQLAVADAGVEWKDIQAATGGSWTVANPDAI
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEEECCCCCE
VGMVGLSGIPFTNVFNACATAASAAKACADGIRLGDYDIGIAIGLDKHPRGAFTEDPALV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCCCCCCCCCCCCCEE
GMPRWYAENGQYLTTQFFGMKANRYLHQHGISQRTLAKVAAKNFRNGARNPNAFRRKPIP
CCCHHCCCCCCEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCC
EDEILNSPMLNYPLTQYMFCAPDEGAAAVVMCRADIAHRYSAKPVYLRAVEVRTRRYGAY
HHHHHCCCCCCCCHHHEEEECCCCCCEEEEEEEHHHHHHCCCCCEEEEEEEEHHHHCCEE
EVNTTFAPVDEDVAPTVYAARAAFEKAGVAPQDVDVIQLQDTDAGAEIIHMAECGFCADG
EECCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCC
EQEKLLADGVTEITGAMPINTDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVAGEP
CHHHHHHCCHHHHHCCCEECCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
RVGFAQLYGAPGTAAATILTT
CCCHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]