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The map label for this gene is orn [H]

Identifier: 41408418

GI number: 41408418

Start: 2602162

End: 2602809

Strand: Direct

Name: orn [H]

Synonym: MAP2320

Alternate gene names: 41408418

Gene position: 2602162-2602809 (Clockwise)

Preceding gene: 41408416

Following gene: 41408419

Centisome position: 53.88

GC content: 66.2

Gene sequence:

>648_bases
GTGCGCGACGAATTGGTGTGGATCGACTGCGAAATGACCGGACTCGATCTCGGTTCGGACAAGCTGATCGAGATCGCGGC
CCTGGTCACCGACGCTGAACTGAATGTGCTCGGCGACGGCGTCGACGTGGTGATCCACGCCGACGACGCCGCGCTGGCGG
CGATGGGCGAGGTGGTCACCGAAATGCATTCGCGCTCCGGGCTGATCGATGAGGTGAAGGCATCCACGGTCGACCTGGCC
ACCGCCGAGGAGATGGTGCTGGACTACATCCGCACTCACGTCAAGGCCCCCAAGACGGCGCCGCTGGCCGGGAATTCGAT
TGCCACCGACCGCGCGTTCATCGTGCGCGACATGCCCGCCCTGGACGCCTACCTGCACTACCGCATGATCGATGTGAGCT
CCATCAAGGAGCTCTGCCGGCGCTGGTACCCGCGGATCTACTTCGGCCAGCCGGTCAAAGGGCTGACCCACCGGGCCCTG
GCCGACATCCACGAATCCATCCGGGAGCTGCAGTTCTACCGGCGCACCGCGTTCGTCGCCCCGCCGGGACCGTCTACCAG
CGAAATCGAGGCGGTGGCCGCCGCCCTCGACGAGGGAAAAGACGCACCGGGACCTAGCGATTCGGCCAGCGCACCGCCCA
CCGGTTAG

Upstream 100 bases:

>100_bases
TGATTCGGCATGCACTTCGCCAACGCTCACCCTACGTCGCGGGCCGATCCGGGGGCGAGGGCCGGCACGGAGGTCGCCGC
CCCGCATTAGGGTGAGCGCT

Downstream 100 bases:

>100_bases
TATCGACGTCGCCGCGTTCACCCGCACCGGGATCGGATGGCGGCCATGGTGGCTGTAGTTCAGCTGGTAGAGCACCAGGT
TGTGATCCTGGGTGTCGCGG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRDELVWIDCEMTGLDLGSDKLIEIAALVTDAELNVLGDGVDVVIHADDAALAAMGEVVTEMHSRSGLIDEVKASTVDLA
TAEEMVLDYIRTHVKAPKTAPLAGNSIATDRAFIVRDMPALDAYLHYRMIDVSSIKELCRRWYPRIYFGQPVKGLTHRAL
ADIHESIRELQFYRRTAFVAPPGPSTSEIEAVAAALDEGKDAPGPSDSASAPPTG

Sequences:

>Translated_215_residues
MRDELVWIDCEMTGLDLGSDKLIEIAALVTDAELNVLGDGVDVVIHADDAALAAMGEVVTEMHSRSGLIDEVKASTVDLA
TAEEMVLDYIRTHVKAPKTAPLAGNSIATDRAFIVRDMPALDAYLHYRMIDVSSIKELCRRWYPRIYFGQPVKGLTHRAL
ADIHESIRELQFYRRTAFVAPPGPSTSEIEAVAAALDEGKDAPGPSDSASAPPTG
>Mature_215_residues
MRDELVWIDCEMTGLDLGSDKLIEIAALVTDAELNVLGDGVDVVIHADDAALAAMGEVVTEMHSRSGLIDEVKASTVDLA
TAEEMVLDYIRTHVKAPKTAPLAGNSIATDRAFIVRDMPALDAYLHYRMIDVSSIKELCRRWYPRIYFGQPVKGLTHRAL
ADIHESIRELQFYRRTAFVAPPGPSTSEIEAVAAALDEGKDAPGPSDSASAPPTG

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides [H]

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI224496106, Length=178, Percent_Identity=48.314606741573, Blast_Score=182, Evalue=1e-46,
Organism=Escherichia coli, GI87082382, Length=172, Percent_Identity=48.8372093023256, Blast_Score=165, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17557752, Length=185, Percent_Identity=45.945945945946, Blast_Score=167, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=196, Percent_Identity=40.3061224489796, Blast_Score=136, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21355135, Length=176, Percent_Identity=47.7272727272727, Blast_Score=172, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 23290; Mature: 23290

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDELVWIDCEMTGLDLGSDKLIEIAALVTDAELNVLGDGVDVVIHADDAALAAMGEVVT
CCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCHHEEECCCEEEEEECCCHHHHHHHHHHH
EMHSRSGLIDEVKASTVDLATAEEMVLDYIRTHVKAPKTAPLAGNSIATDRAFIVRDMPA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCHH
LDAYLHYRMIDVSSIKELCRRWYPRIYFGQPVKGLTHRALADIHESIRELQFYRRTAFVA
HHHHHHHHEECHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEC
PPGPSTSEIEAVAAALDEGKDAPGPSDSASAPPTG
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDELVWIDCEMTGLDLGSDKLIEIAALVTDAELNVLGDGVDVVIHADDAALAAMGEVVT
CCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCHHEEECCCEEEEEECCCHHHHHHHHHHH
EMHSRSGLIDEVKASTVDLATAEEMVLDYIRTHVKAPKTAPLAGNSIATDRAFIVRDMPA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCHH
LDAYLHYRMIDVSSIKELCRRWYPRIYFGQPVKGLTHRALADIHESIRELQFYRRTAFVA
HHHHHHHHEECHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEC
PPGPSTSEIEAVAAALDEGKDAPGPSDSASAPPTG
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA