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The map label for this gene is eccA5 [H]

Identifier: 41407611

GI number: 41407611

Start: 1661750

End: 1663582

Strand: Direct

Name: eccA5 [H]

Synonym: MAP1513

Alternate gene names: 41407611

Gene position: 1661750-1663582 (Clockwise)

Preceding gene: 41407610

Following gene: 41407612

Centisome position: 34.41

GC content: 68.25

Gene sequence:

>1833_bases
ATGACGCGGCCGCAGTCCACCGCTGAGGGCGCCCGCAACGCCATGGTCGCCGGCCTGCTGGCATCGGGGGTGTCGGTCAA
CGGGTTACAGCCCAGCCACAATCCACAGGTCGCGGCGCAGATGTTCACCACCGCGACCAACCTGGATCCCACCATGTGTG
ACGCCTGGCTGGCGCGGATCCTGGCGGGGGAGCAGAGCCTCGACGTGCTGGCCGGTGCCTGGTCCTCCATCCGCACGTTC
GGCTGGGAGACCCGCCGCCTGGGCGTCACCGAATTGCAGTTCCGCCCAGAGGTTTCCGACGGCCTGTTCCTGCAGCTGGC
CGTCACCAGCGTGGAATCGCTGGCGTGCGCCTACGCCGTGGTGCTCGCCGAGGCGAAGCACTACGCTGAGGCGGCCAAAC
TGATCGACGGCGTCGAACCGCGCCAGCCGGTGGACGGAGAGCTGCTCTCCTACGTGCGCGGCGTGCTGTACTTCCGCACC
GGCCGGTGGCCGGACGTGCTCAACCAGTTCCCCGAGGGCAAGGGCTGGCGCCAGCCCGAGCTGAAGGCCGCCGGGGCGGC
CATGGCCACCACGGCGCTGGCCTCGCTCGGGGTGTTCGAGGAGGCGCTGCGCCGCGGCCAGGAGGCCATCGAGGGCGACC
GGGTGCCGGGCGCGGCCAACATCGCCCTGTACACCCAGGGCATGTGCCTCCGGCACCTGGGCCGCGAGGACGAGGCCGTC
GAACTGCTGCGGCGGGTGTATTCGCGCGACCCCAAGTTCACCCCGGCCCGCGAAGCGCTGGACAACCCCACCTACCGGCT
GGTGTTGACCGACCCGGAAACGATCGAGGCCCGCACCGACCCGTGGGACCCCGACAGCGCGCCCACCCGCGCCGAAGCCG
AAGCCGCCCGCCACGCCGAGGAGGCGGCCAAGTACCTGGCCGAAGGCGACGCCGAACTCAACGCCATGCTGGGCATGGAG
CGGGCCAAGCGCGAGATCAAGCTGATCAAGTCGACGACGAAGGTGAACCTGGCCCGCGCCAAGATGGGACTCCCGGTGCC
GGTGACGTCGCGCCACACCCTGCTGCTGGGCCCGCCGGGAACCGGAAAGACCTCGGTGGCAAGGGCTTTCACCAAGCAGC
TGTGCGGGTTGACGGTGCTGCGCAAGCCGCTGGTGGTGGAGACCAGCCGCACCAAGCTGTTGGGCCGATACATGGCCGAC
GCCGAGAAGAACACCGAGGAGATGCTCGAGGGCGCCCTGGGCGGCGCGGTGTTCTTCGACGAGATGCACACCCTGCACGA
GAAGGGCTACCAGCAGGGTGACCCGTACGGCAACGCGATCATCAACACCTTGCTGCTGTACATGGAGAACCATCGCGACG
AGCTGGTGGTCTTCGGCGCCGGCTACGCCAAGGCCATGGACAAGATGCTCGAGGTGAATCAGGGTCTGCGACGGCGCTTT
TCGACCGTGATCGAGTTCTTCAGCTACACCCCGGACGAACTGGTCGCGCTGACCCGGTTGATGGGCCAGGAGAACGAGGA
CGTCATCACCGACGAAGCGGCGCAGGCCCTGCTGCCGTCGTACACCAAGTTCTATCTCGACGAAAGCTATTCGGAGGACG
GCGATCTCATCCGCGGCATCGACACGCTGGGCAACGCCGGCTTCGTGCGCAACGTGGTGGAGAAGGCGCGCGATCACCGC
AGCTTCCGGCTGGACGACGAGGACCTGGATGCCGTGCTGGCCAGCGACGGGACCGAGTTCAGCGAGCGCCAGCTGCTGCG
TTTCAAGGAGCTGACCCGCGAGGACCTCGCCGAGGGCCTCAGCGCGGCGGTGGCAGAGAAGAAGACCACCTAG

Upstream 100 bases:

>100_bases
TGCTGGAGGTGCCGAGCCGTCCGCTGCGCGCCGACGATGACGAGCTGTCGCTATCGCTCGCTGCACCCCGGGAGAGCGCG
GCGGGCGTACCCGTGGCGCA

Downstream 100 bases:

>100_bases
CCTTCCCCCGAGGTGACGCGGGCGTGAACCGTTGGTATCGCGTTGTGGATCAGCTTGACTAGCCGACCCCCGAGTGCCAC
CATTGCCAATGCAAGCACCT

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component A5; Type VII secretion system protein EccA5; T7SS protein EccA5 [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MTRPQSTAEGARNAMVAGLLASGVSVNGLQPSHNPQVAAQMFTTATNLDPTMCDAWLARILAGEQSLDVLAGAWSSIRTF
GWETRRLGVTELQFRPEVSDGLFLQLAVTSVESLACAYAVVLAEAKHYAEAAKLIDGVEPRQPVDGELLSYVRGVLYFRT
GRWPDVLNQFPEGKGWRQPELKAAGAAMATTALASLGVFEEALRRGQEAIEGDRVPGAANIALYTQGMCLRHLGREDEAV
ELLRRVYSRDPKFTPAREALDNPTYRLVLTDPETIEARTDPWDPDSAPTRAEAEAARHAEEAAKYLAEGDAELNAMLGME
RAKREIKLIKSTTKVNLARAKMGLPVPVTSRHTLLLGPPGTGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRYMAD
AEKNTEEMLEGALGGAVFFDEMHTLHEKGYQQGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRF
STVIEFFSYTPDELVALTRLMGQENEDVITDEAAQALLPSYTKFYLDESYSEDGDLIRGIDTLGNAGFVRNVVEKARDHR
SFRLDDEDLDAVLASDGTEFSERQLLRFKELTREDLAEGLSAAVAEKKTT

Sequences:

>Translated_610_residues
MTRPQSTAEGARNAMVAGLLASGVSVNGLQPSHNPQVAAQMFTTATNLDPTMCDAWLARILAGEQSLDVLAGAWSSIRTF
GWETRRLGVTELQFRPEVSDGLFLQLAVTSVESLACAYAVVLAEAKHYAEAAKLIDGVEPRQPVDGELLSYVRGVLYFRT
GRWPDVLNQFPEGKGWRQPELKAAGAAMATTALASLGVFEEALRRGQEAIEGDRVPGAANIALYTQGMCLRHLGREDEAV
ELLRRVYSRDPKFTPAREALDNPTYRLVLTDPETIEARTDPWDPDSAPTRAEAEAARHAEEAAKYLAEGDAELNAMLGME
RAKREIKLIKSTTKVNLARAKMGLPVPVTSRHTLLLGPPGTGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRYMAD
AEKNTEEMLEGALGGAVFFDEMHTLHEKGYQQGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRF
STVIEFFSYTPDELVALTRLMGQENEDVITDEAAQALLPSYTKFYLDESYSEDGDLIRGIDTLGNAGFVRNVVEKARDHR
SFRLDDEDLDAVLASDGTEFSERQLLRFKELTREDLAEGLSAAVAEKKTT
>Mature_609_residues
TRPQSTAEGARNAMVAGLLASGVSVNGLQPSHNPQVAAQMFTTATNLDPTMCDAWLARILAGEQSLDVLAGAWSSIRTFG
WETRRLGVTELQFRPEVSDGLFLQLAVTSVESLACAYAVVLAEAKHYAEAAKLIDGVEPRQPVDGELLSYVRGVLYFRTG
RWPDVLNQFPEGKGWRQPELKAAGAAMATTALASLGVFEEALRRGQEAIEGDRVPGAANIALYTQGMCLRHLGREDEAVE
LLRRVYSRDPKFTPAREALDNPTYRLVLTDPETIEARTDPWDPDSAPTRAEAEAARHAEEAAKYLAEGDAELNAMLGMER
AKREIKLIKSTTKVNLARAKMGLPVPVTSRHTLLLGPPGTGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRYMADA
EKNTEEMLEGALGGAVFFDEMHTLHEKGYQQGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRFS
TVIEFFSYTPDELVALTRLMGQENEDVITDEAAQALLPSYTKFYLDESYSEDGDLIRGIDTLGNAGFVRNVVEKARDHRS
FRLDDEDLDAVLASDGTEFSERQLLRFKELTREDLAEGLSAAVAEKKTT

Specific function: Shows ATPase activity. Could provide energy for export of ESX-5 substrates [H]

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: NA

Molecular weight: Translated: 67169; Mature: 67038

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPQSTAEGARNAMVAGLLASGVSVNGLQPSHNPQVAAQMFTTATNLDPTMCDAWLARI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
LAGEQSLDVLAGAWSSIRTFGWETRRLGVTELQFRPEVSDGLFLQLAVTSVESLACAYAV
HCCCCHHHHHHHHHHHHHHCCCCHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHH
VLAEAKHYAEAAKLIDGVEPRQPVDGELLSYVRGVLYFRTGRWPDVLNQFPEGKGWRQPE
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCH
LKAAGAAMATTALASLGVFEEALRRGQEAIEGDRVPGAANIALYTQGMCLRHLGREDEAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCCCCHHH
ELLRRVYSRDPKFTPAREALDNPTYRLVLTDPETIEARTDPWDPDSAPTRAEAEAARHAE
HHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EAAKYLAEGDAELNAMLGMERAKREIKLIKSTTKVNLARAKMGLPVPVTSRHTLLLGPPG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
TGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRYMADAEKNTEEMLEGALGGAVFFD
CCHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHH
EMHTLHEKGYQQGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
STVIEFFSYTPDELVALTRLMGQENEDVITDEAAQALLPSYTKFYLDESYSEDGDLIRGI
HHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DTLGNAGFVRNVVEKARDHRSFRLDDEDLDAVLASDGTEFSERQLLRFKELTREDLAEGL
HHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SAAVAEKKTT
HHHHHHCCCC
>Mature Secondary Structure 
TRPQSTAEGARNAMVAGLLASGVSVNGLQPSHNPQVAAQMFTTATNLDPTMCDAWLARI
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
LAGEQSLDVLAGAWSSIRTFGWETRRLGVTELQFRPEVSDGLFLQLAVTSVESLACAYAV
HCCCCHHHHHHHHHHHHHHCCCCHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHH
VLAEAKHYAEAAKLIDGVEPRQPVDGELLSYVRGVLYFRTGRWPDVLNQFPEGKGWRQPE
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCH
LKAAGAAMATTALASLGVFEEALRRGQEAIEGDRVPGAANIALYTQGMCLRHLGREDEAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCCCCHHH
ELLRRVYSRDPKFTPAREALDNPTYRLVLTDPETIEARTDPWDPDSAPTRAEAEAARHAE
HHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EAAKYLAEGDAELNAMLGMERAKREIKLIKSTTKVNLARAKMGLPVPVTSRHTLLLGPPG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
TGKTSVARAFTKQLCGLTVLRKPLVVETSRTKLLGRYMADAEKNTEEMLEGALGGAVFFD
CCHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHH
EMHTLHEKGYQQGDPYGNAIINTLLLYMENHRDELVVFGAGYAKAMDKMLEVNQGLRRRF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
STVIEFFSYTPDELVALTRLMGQENEDVITDEAAQALLPSYTKFYLDESYSEDGDLIRGI
HHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DTLGNAGFVRNVVEKARDHRSFRLDDEDLDAVLASDGTEFSERQLLRFKELTREDLAEGL
HHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SAAVAEKKTT
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]