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The map label for this gene is bcd [H]

Identifier: 41407557

GI number: 41407557

Start: 1597420

End: 1598556

Strand: Direct

Name: bcd [H]

Synonym: MAP1459

Alternate gene names: 41407557

Gene position: 1597420-1598556 (Clockwise)

Preceding gene: 41407556

Following gene: 41407558

Centisome position: 33.07

GC content: 73.53

Gene sequence:

>1137_bases
ATGAAACTGACGCCGACCGCCGAACAGCGCGACTTCGCGGCGTCGCTGCGCGCGCTGCTGGCCGCCGAGAACCCGCTGCA
CCTGGTGCGAGCGCTGAACGAACCGGACGCCGACCGCCGCACCCCCGCATTGTGGAAGGCGCTGAGCGGCGCGGGCGTCT
TCGGCCTGGCCATCGCCGAGGAGTACGGCGGCTCCGGCGGCTCGCTGGACGACCTGGCGGTCTTCTACACCGAAGCCGGC
CGGGCGCTGTGCCCGACGACGGTGCACAACAGCGTGCAGGCAGCCCTGGCCGTCGACCGGCTCGGGTCCCGGGACGCCAA
GGCCCGGTGGTTGCCGCCGCTGGTGTCGGGCAGCCTGCGCGCCACCACCGCGCTGTGGAACGCCCGCGACGCCGCGCTGG
TGTCCCCGGTCCTGCGCGCCGATCGGGTCGAAGCACCGGCCTCCCAGTGGCGGGTGAACGGAACCGTCGACTACGTCGCC
GACGCCGACGTCGCCGACCTCGTCGTGGCATCGGCCGCCGCGGCCGGGCGGACACTGGTGTTCCTGGTCGACCCGCACAC
CGAGGGCGTGAGCCTGGCGCCGCTGGACATGGCCGGCGGGCACCGGGCCTTCGCGGTCCGCTTCGACGACGTGGCGATCG
GCGACGACGCGGTGCTCGACGCCGTGGCCGCGGGCGTCATCCCGACCGCCCTGCGCCGGCTGGCCAACACCGCGGTGGCG
TTGGGCTCGCTCGACCTGGTCGGCGTCGGGCAGGCCGTGCTGGACCGCACCGTCGACTACACCAAGCTGCGTCACCAATT
CGGCCGGTCCATCGCCTCGTTTCAGGCCGCCCAGCACGTGGTCGCCAACATGCACATCGCGCTGGCGGCGGCGCGCTTGG
CCGCGCACGCGGCGGTGTTCTGGCTGGGACGCGGCCGCACCGCGAGCCGGGAGACGGCCGTCGCGCGCATGCATGCGGCC
ACCGCTGCCCGGCTGATCACGCTCGACGCGCACCAGCTGCACGGCGGCATGGGCTATGTCACCGAGACCGACCTGCATCT
GTGGAGCGAACGGGCCCGGCTCGGTTCGACGCTGGGCGGCGGCGCCGATGTCGCCGCATCGTGGCTCGAACAAACCTGGG
AGGAGATCGGTGAGTGA

Upstream 100 bases:

>100_bases
CGCTTCGGCGGGGGCGCCAACGAGGTGCTGCGCGACATCATCGCCCAGCGCGGGCACGCCATGCCGAGCTACGGACGCTG
ACCCGGACCCGACCACCCAG

Downstream 100 bases:

>100_bases
GGACAGCTTGGTCGACGCCGAGTCGGCGGCGCGGGTGGGTACGGTCGCCGCGTCGGCGACCGGCGAAGTGAACCAACGGG
ATTGGCAGCGCTGGGCCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKLTPTAEQRDFAASLRALLAAENPLHLVRALNEPDADRRTPALWKALSGAGVFGLAIAEEYGGSGGSLDDLAVFYTEAG
RALCPTTVHNSVQAALAVDRLGSRDAKARWLPPLVSGSLRATTALWNARDAALVSPVLRADRVEAPASQWRVNGTVDYVA
DADVADLVVASAAAAGRTLVFLVDPHTEGVSLAPLDMAGGHRAFAVRFDDVAIGDDAVLDAVAAGVIPTALRRLANTAVA
LGSLDLVGVGQAVLDRTVDYTKLRHQFGRSIASFQAAQHVVANMHIALAAARLAAHAAVFWLGRGRTASRETAVARMHAA
TAARLITLDAHQLHGGMGYVTETDLHLWSERARLGSTLGGGADVAASWLEQTWEEIGE

Sequences:

>Translated_378_residues
MKLTPTAEQRDFAASLRALLAAENPLHLVRALNEPDADRRTPALWKALSGAGVFGLAIAEEYGGSGGSLDDLAVFYTEAG
RALCPTTVHNSVQAALAVDRLGSRDAKARWLPPLVSGSLRATTALWNARDAALVSPVLRADRVEAPASQWRVNGTVDYVA
DADVADLVVASAAAAGRTLVFLVDPHTEGVSLAPLDMAGGHRAFAVRFDDVAIGDDAVLDAVAAGVIPTALRRLANTAVA
LGSLDLVGVGQAVLDRTVDYTKLRHQFGRSIASFQAAQHVVANMHIALAAARLAAHAAVFWLGRGRTASRETAVARMHAA
TAARLITLDAHQLHGGMGYVTETDLHLWSERARLGSTLGGGADVAASWLEQTWEEIGE
>Mature_378_residues
MKLTPTAEQRDFAASLRALLAAENPLHLVRALNEPDADRRTPALWKALSGAGVFGLAIAEEYGGSGGSLDDLAVFYTEAG
RALCPTTVHNSVQAALAVDRLGSRDAKARWLPPLVSGSLRATTALWNARDAALVSPVLRADRVEAPASQWRVNGTVDYVA
DADVADLVVASAAAAGRTLVFLVDPHTEGVSLAPLDMAGGHRAFAVRFDDVAIGDDAVLDAVAAGVIPTALRRLANTAVA
LGSLDLVGVGQAVLDRTVDYTKLRHQFGRSIASFQAAQHVVANMHIALAAARLAAHAAVFWLGRGRTASRETAVARMHAA
TAARLITLDAHQLHGGMGYVTETDLHLWSERARLGSTLGGGADVAASWLEQTWEEIGE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=334, Percent_Identity=29.3413173652695, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=25.2659574468085, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI226958412, Length=386, Percent_Identity=26.1658031088083, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226958414, Length=350, Percent_Identity=27.1428571428571, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI7656849, Length=323, Percent_Identity=25.077399380805, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=20.855614973262, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4557235, Length=320, Percent_Identity=24.6875, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI76496475, Length=328, Percent_Identity=24.6951219512195, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=21.6710182767624, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=21.6710182767624, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI21361497, Length=330, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=328, Percent_Identity=27.1341463414634, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17538396, Length=322, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=354, Percent_Identity=25.1412429378531, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=295, Percent_Identity=25.7627118644068, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=336, Percent_Identity=24.4047619047619, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=358, Percent_Identity=25.1396648044693, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17505929, Length=352, Percent_Identity=25.5681818181818, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32563615, Length=238, Percent_Identity=26.0504201680672, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71985184, Length=276, Percent_Identity=24.2753623188406, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=328, Percent_Identity=24.0853658536585, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355753, Length=365, Percent_Identity=25.4794520547945, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=24.8663101604278, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356377, Length=327, Percent_Identity=27.217125382263, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646207, Length=326, Percent_Identity=25.7668711656442, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24660351, Length=287, Percent_Identity=26.1324041811847, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281363737, Length=361, Percent_Identity=21.3296398891967, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 39731; Mature: 39731

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTPTAEQRDFAASLRALLAAENPLHLVRALNEPDADRRTPALWKALSGAGVFGLAIAE
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEHHHHHH
EYGGSGGSLDDLAVFYTEAGRALCPTTVHNSVQAALAVDRLGSRDAKARWLPPLVSGSLR
HHCCCCCCHHHHHHEEECCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCH
ATTALWNARDAALVSPVLRADRVEAPASQWRVNGTVDYVADADVADLVVASAAAAGRTLV
HHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEECCEEEEECCCCHHHHHHHHHHCCCCEEE
FLVDPHTEGVSLAPLDMAGGHRAFAVRFDDVAIGDDAVLDAVAAGVIPTALRRLANTAVA
EEECCCCCCCEECCEECCCCCEEEEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLDLVGVGQAVLDRTVDYTKLRHQFGRSIASFQAAQHVVANMHIALAAARLAAHAAVF
HCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
WLGRGRTASRETAVARMHAATAARLITLDAHQLHGGMGYVTETDLHLWSERARLGSTLGG
EEECCCCCCHHHHHHHHHHHHHHHEEEEEHHHHCCCCCCEEECHHHHHHHHHHHCCCCCC
GADVAASWLEQTWEEIGE
CHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLTPTAEQRDFAASLRALLAAENPLHLVRALNEPDADRRTPALWKALSGAGVFGLAIAE
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEHHHHHH
EYGGSGGSLDDLAVFYTEAGRALCPTTVHNSVQAALAVDRLGSRDAKARWLPPLVSGSLR
HHCCCCCCHHHHHHEEECCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCH
ATTALWNARDAALVSPVLRADRVEAPASQWRVNGTVDYVADADVADLVVASAAAAGRTLV
HHHHHHCCCHHHHHHHHHHHHHCCCCHHHEEECCEEEEECCCCHHHHHHHHHHCCCCEEE
FLVDPHTEGVSLAPLDMAGGHRAFAVRFDDVAIGDDAVLDAVAAGVIPTALRRLANTAVA
EEECCCCCCCEECCEECCCCCEEEEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGSLDLVGVGQAVLDRTVDYTKLRHQFGRSIASFQAAQHVVANMHIALAAARLAAHAAVF
HCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
WLGRGRTASRETAVARMHAATAARLITLDAHQLHGGMGYVTETDLHLWSERARLGSTLGG
EEECCCCCCHHHHHHHHHHHHHHHEEEEEHHHHCCCCCCEEECHHHHHHHHHHHCCCCCC
GADVAASWLEQTWEEIGE
CHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]