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The map label for this gene is yngJ [H]

Identifier: 41407556

GI number: 41407556

Start: 1596222

End: 1597400

Strand: Direct

Name: yngJ [H]

Synonym: MAP1458

Alternate gene names: 41407556

Gene position: 1596222-1597400 (Clockwise)

Preceding gene: 41407555

Following gene: 41407557

Centisome position: 33.05

GC content: 69.04

Gene sequence:

>1179_bases
ATGGATTTCGAACTCGACGCGGGGCAGCGCGCCTGGCTGGCCGAGATTCGCGAATTCCTGCGCGACAACGTCACCGAGGA
GTTGCGGGCCGAGCTCGCCCAACACGATCTCGAGTTTCCCGACGGCGAAGTGGCCCGGTTCCGGCGCAAGATCGGCGCCA
AGGGCTGGTTCGGGCTGAACTGGCCCCGCGAGTACGGCGGCCTGGGGCTGGGCGCGGTGCACCTGCACCTGCTGATGAGC
GAATTCGAATACTGGGGCGTGCCGGGCCCCGACCTGACCGTGACGTCGGTGGCGCCGATGATCATGCGGCACGGCACCGA
ACGCAACAAAACCGAATGGCTGCCGCTGATCGCCAAGGGCGAAATGATCTGTGCGGTCGGCTATTCCGAGCCCGACGCGG
GAACCGACCTGGCCAACCTGCGCACCAGCGCCGTGCGCGACGGCGAGGAGTGGGTGATCAACGGCACCAAGATCTGGAAC
AGCGGGGCGCAGCGGGCGACGCACGAATGGCTCTGTGTGCGCACCGATCCCACCGGCACCCGGCATCGCGGCATCTCGGT
CGTCATCGTCCCCATCGACAGCCCCGGGATCGACATCCGCCCGCTGTACGCGTGGTCGGGCTACCGCACCAACGAGGTGC
ACTTCCATGACGTGCGGGTGCCGGTCACCAATCTGATCGGCGAAGTCAACCACGGCTGGACCTACATCACCGGCGCGCTC
GATCTCGAACGGGGAGCCCTGACCAACGCGGGCGACCTGCGCCGCGCCGTCGAGGAACTGCACGAGCTGGCGCGGCGGCC
GCGCCGCGACCGGACGGTGCCCGCCGACGACCCGTGGCTGTGCCGCCGGCTGGCGCAGGCCGAAGCCGACGTGGCGGTGG
CCACCCTGATGGGCTACGAGGCGGCGTCGATCCTGGACAGCGGCGTCATCCCGACCGTCGAGGTCAGCGTCGAAAAGATC
TTCACCAGCGAGCTGCGTCAGCGCATCGCGGATCTGGCGCTCGACCTGCTCGGAGTGGACGGGCTGCTGGCGCATCGCAG
CGAAAACGCCCCGCTGGCAGGCAAATTCGAGCGGCTCTACCGGGCGGCCCCGCTGATGCGCTTCGGCGGGGGCGCCAACG
AGGTGCTGCGCGACATCATCGCCCAGCGCGGGCACGCCATGCCGAGCTACGGACGCTGA

Upstream 100 bases:

>100_bases
CCGGGCGCATTCTCGCCGTGGCGTTACGCTGGCGCTGCTCGGTGTAAGGCTCGGTCTGAGGCCGACGGAAAGGCACCCGC
AGAAAGGCACAGGCGCCGGA

Downstream 100 bases:

>100_bases
CCCGGACCCGACCACCCAGATGAAACTGACGCCGACCGCCGAACAGCGCGACTTCGCGGCGTCGCTGCGCGCGCTGCTGG
CCGCCGAGAACCCGCTGCAC

Product: hypothetical protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MDFELDAGQRAWLAEIREFLRDNVTEELRAELAQHDLEFPDGEVARFRRKIGAKGWFGLNWPREYGGLGLGAVHLHLLMS
EFEYWGVPGPDLTVTSVAPMIMRHGTERNKTEWLPLIAKGEMICAVGYSEPDAGTDLANLRTSAVRDGEEWVINGTKIWN
SGAQRATHEWLCVRTDPTGTRHRGISVVIVPIDSPGIDIRPLYAWSGYRTNEVHFHDVRVPVTNLIGEVNHGWTYITGAL
DLERGALTNAGDLRRAVEELHELARRPRRDRTVPADDPWLCRRLAQAEADVAVATLMGYEAASILDSGVIPTVEVSVEKI
FTSELRQRIADLALDLLGVDGLLAHRSENAPLAGKFERLYRAAPLMRFGGGANEVLRDIIAQRGHAMPSYGR

Sequences:

>Translated_392_residues
MDFELDAGQRAWLAEIREFLRDNVTEELRAELAQHDLEFPDGEVARFRRKIGAKGWFGLNWPREYGGLGLGAVHLHLLMS
EFEYWGVPGPDLTVTSVAPMIMRHGTERNKTEWLPLIAKGEMICAVGYSEPDAGTDLANLRTSAVRDGEEWVINGTKIWN
SGAQRATHEWLCVRTDPTGTRHRGISVVIVPIDSPGIDIRPLYAWSGYRTNEVHFHDVRVPVTNLIGEVNHGWTYITGAL
DLERGALTNAGDLRRAVEELHELARRPRRDRTVPADDPWLCRRLAQAEADVAVATLMGYEAASILDSGVIPTVEVSVEKI
FTSELRQRIADLALDLLGVDGLLAHRSENAPLAGKFERLYRAAPLMRFGGGANEVLRDIIAQRGHAMPSYGR
>Mature_392_residues
MDFELDAGQRAWLAEIREFLRDNVTEELRAELAQHDLEFPDGEVARFRRKIGAKGWFGLNWPREYGGLGLGAVHLHLLMS
EFEYWGVPGPDLTVTSVAPMIMRHGTERNKTEWLPLIAKGEMICAVGYSEPDAGTDLANLRTSAVRDGEEWVINGTKIWN
SGAQRATHEWLCVRTDPTGTRHRGISVVIVPIDSPGIDIRPLYAWSGYRTNEVHFHDVRVPVTNLIGEVNHGWTYITGAL
DLERGALTNAGDLRRAVEELHELARRPRRDRTVPADDPWLCRRLAQAEADVAVATLMGYEAASILDSGVIPTVEVSVEKI
FTSELRQRIADLALDLLGVDGLLAHRSENAPLAGKFERLYRAAPLMRFGGGANEVLRDIIAQRGHAMPSYGR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=393, Percent_Identity=29.0076335877863, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4557231, Length=394, Percent_Identity=27.1573604060914, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI187960098, Length=394, Percent_Identity=27.1573604060914, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4501857, Length=389, Percent_Identity=26.4781491002571, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=26.6318537859008, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226958412, Length=391, Percent_Identity=26.0869565217391, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4501859, Length=348, Percent_Identity=27.0114942528736, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226958414, Length=353, Percent_Identity=26.9121813031161, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI76496475, Length=348, Percent_Identity=28.1609195402299, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4557235, Length=348, Percent_Identity=28.1609195402299, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI38505218, Length=293, Percent_Identity=29.0102389078498, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI48976061, Length=405, Percent_Identity=28.1481481481481, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI211971008, Length=405, Percent_Identity=28.1481481481481, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7656849, Length=387, Percent_Identity=25.0645994832041, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=24.4094488188976, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081958, Length=384, Percent_Identity=24.21875, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=395, Percent_Identity=27.3417721518987, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17569725, Length=348, Percent_Identity=26.4367816091954, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17570075, Length=394, Percent_Identity=24.6192893401015, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=25.4010695187166, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=343, Percent_Identity=25.0728862973761, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=343, Percent_Identity=26.8221574344023, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=384, Percent_Identity=25, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=349, Percent_Identity=26.0744985673352, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=25.9786476868327, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=343, Percent_Identity=23.6151603498542, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=201, Percent_Identity=28.8557213930348, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=296, Percent_Identity=25.6756756756757, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=211, Percent_Identity=28.9099526066351, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562446, Length=376, Percent_Identity=26.3297872340426, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=169, Percent_Identity=28.9940828402367, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281363737, Length=348, Percent_Identity=27.2988505747126, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355753, Length=385, Percent_Identity=24.9350649350649, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646207, Length=389, Percent_Identity=27.7634961439589, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24666513, Length=340, Percent_Identity=26.4705882352941, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=25.7978723404255, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=27.012987012987, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 43696; Mature: 43696

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFELDAGQRAWLAEIREFLRDNVTEELRAELAQHDLEFPDGEVARFRRKIGAKGWFGLN
CCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
WPREYGGLGLGAVHLHLLMSEFEYWGVPGPDLTVTSVAPMIMRHGTERNKTEWLPLIAKG
CCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCEEEECC
EMICAVGYSEPDAGTDLANLRTSAVRDGEEWVINGTKIWNSGAQRATHEWLCVRTDPTGT
CEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCCCCCCCCCEEEEECCCCCC
RHRGISVVIVPIDSPGIDIRPLYAWSGYRTNEVHFHDVRVPVTNLIGEVNHGWTYITGAL
CCCCEEEEEEECCCCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHCCCCCEEEEEEEE
DLERGALTNAGDLRRAVEELHELARRPRRDRTVPADDPWLCRRLAQAEADVAVATLMGYE
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AASILDSGVIPTVEVSVEKIFTSELRQRIADLALDLLGVDGLLAHRSENAPLAGKFERLY
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHH
RAAPLMRFGGGANEVLRDIIAQRGHAMPSYGR
HHCCHHHCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDFELDAGQRAWLAEIREFLRDNVTEELRAELAQHDLEFPDGEVARFRRKIGAKGWFGLN
CCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
WPREYGGLGLGAVHLHLLMSEFEYWGVPGPDLTVTSVAPMIMRHGTERNKTEWLPLIAKG
CCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCEEEECC
EMICAVGYSEPDAGTDLANLRTSAVRDGEEWVINGTKIWNSGAQRATHEWLCVRTDPTGT
CEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCCCCCCCCCEEEEECCCCCC
RHRGISVVIVPIDSPGIDIRPLYAWSGYRTNEVHFHDVRVPVTNLIGEVNHGWTYITGAL
CCCCEEEEEEECCCCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHCCCCCEEEEEEEE
DLERGALTNAGDLRRAVEELHELARRPRRDRTVPADDPWLCRRLAQAEADVAVATLMGYE
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AASILDSGVIPTVEVSVEKIFTSELRQRIADLALDLLGVDGLLAHRSENAPLAGKFERLY
HHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHH
RAAPLMRFGGGANEVLRDIIAQRGHAMPSYGR
HHCCHHHCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]