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The map label for this gene is 41407493

Identifier: 41407493

GI number: 41407493

Start: 1508676

End: 1509293

Strand: Direct

Name: 41407493

Synonym: MAP1395

Alternate gene names: NA

Gene position: 1508676-1509293 (Clockwise)

Preceding gene: 41407488

Following gene: 41407494

Centisome position: 31.24

GC content: 76.38

Gene sequence:

>618_bases
TTGCGCGACGCTGCCGAGCAGCTGCTGGTCGACCCGGTCGAGGCTGCCCGCCGGCTGCTGGGCGCCACCCTGACCGGACG
GGGCGTGAGCGGGGTCATCGTCGAGGTCGAGGCGTACGGGGGAGTCCCCGACGGGCCCTGGCCCGACGCCGCGGCGCACT
CCTACAAGGGGCTGCGGGCCCGCAACTTCGTCATGTTCGGCCCGCCCGGGCGGCTCTACACCTACCGCAGCCACGGCATC
CACGTCTGCGCCAACGTGTCCTGCGGGCCCGACGGGACCGCCGCCGCCGTGCTGCTGCGGGCCGCCGCCCTCGAGGACGG
CACCGACGTCGCGCGCGGCCGCCGCGGCGAGTTGGTGCACACCGCGGCGCTGGCCCGCGGCCCGGGCAACCTGTGCGCCG
CCATGGGAATCACCATGGCGGACAACGGAATCGACCTTTTCGACCCGGACTCGCCGGTGACCCTGCGGCTGCACGAGCCG
CTGACCGCGGTGTGCGGGCCGCGGGTCGGGGTCAGCCAGGCCGCCGACCGGCCGTGGCGGCTGTGGCTGCCCGGGCGCCC
GGAGGTGTCGGCCTACCGGCGAAGTCCGCGGGCGCCCGCCCCCGGGACCAGCGACTAA

Upstream 100 bases:

>100_bases
CCTTGGGGTCCCGGGACACCGGGATATTGCCATGTTCGGGCTGCCGGTAGGTTCGTTGGGTTGCTGAAAGGGATCTGACG
TGGTCGAGGCGGGACGACGG

Downstream 100 bases:

>100_bases
AGTCGGCGGCGATGTCTTCCGGGATCCTCGACGAGCTGGGCTGGCGCGGCCTGATCGCGCAGTCCACCGACCTCGACGCG
CTGGCCGCCGAAGCCCGGCC

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MRDAAEQLLVDPVEAARRLLGATLTGRGVSGVIVEVEAYGGVPDGPWPDAAAHSYKGLRARNFVMFGPPGRLYTYRSHGI
HVCANVSCGPDGTAAAVLLRAAALEDGTDVARGRRGELVHTAALARGPGNLCAAMGITMADNGIDLFDPDSPVTLRLHEP
LTAVCGPRVGVSQAADRPWRLWLPGRPEVSAYRRSPRAPAPGTSD

Sequences:

>Translated_205_residues
MRDAAEQLLVDPVEAARRLLGATLTGRGVSGVIVEVEAYGGVPDGPWPDAAAHSYKGLRARNFVMFGPPGRLYTYRSHGI
HVCANVSCGPDGTAAAVLLRAAALEDGTDVARGRRGELVHTAALARGPGNLCAAMGITMADNGIDLFDPDSPVTLRLHEP
LTAVCGPRVGVSQAADRPWRLWLPGRPEVSAYRRSPRAPAPGTSD
>Mature_205_residues
MRDAAEQLLVDPVEAARRLLGATLTGRGVSGVIVEVEAYGGVPDGPWPDAAAHSYKGLRARNFVMFGPPGRLYTYRSHGI
HVCANVSCGPDGTAAAVLLRAAALEDGTDVARGRRGELVHTAALARGPGNLCAAMGITMADNGIDLFDPDSPVTLRLHEP
LTAVCGPRVGVSQAADRPWRLWLPGRPEVSAYRRSPRAPAPGTSD

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=148, Percent_Identity=38.5135135135135, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI62632771, Length=148, Percent_Identity=38.5135135135135, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI62632765, Length=148, Percent_Identity=38.5135135135135, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_MYCPA (Q740F6)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_960329.1
- HSSP:   P29372
- ProteinModelPortal:   Q740F6
- SMR:   Q740F6
- EnsemblBacteria:   EBMYCT00000037602
- GeneID:   2719480
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP1395
- NMPDR:   fig|262316.1.peg.1395
- GeneTree:   EBGT00050000017493
- HOGENOM:   HBG664239
- OMA:   LCSGPGK
- ProtClustDB:   PRK00802
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 21539; Mature: 21539

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDAAEQLLVDPVEAARRLLGATLTGRGVSGVIVEVEAYGGVPDGPWPDAAAHSYKGLRA
CCCHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHCCCCCCC
RNFVMFGPPGRLYTYRSHGIHVCANVSCGPDGTAAAVLLRAAALEDGTDVARGRRGELVH
CCEEEECCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCEEE
TAALARGPGNLCAAMGITMADNGIDLFDPDSPVTLRLHEPLTAVCGPRVGVSQAADRPWR
EHHHHCCCCCEEHHHCEEEECCCCCCCCCCCCEEEEECCCHHHHCCCCCCCHHHCCCCEE
LWLPGRPEVSAYRRSPRAPAPGTSD
EEECCCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRDAAEQLLVDPVEAARRLLGATLTGRGVSGVIVEVEAYGGVPDGPWPDAAAHSYKGLRA
CCCHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHCCCCCCC
RNFVMFGPPGRLYTYRSHGIHVCANVSCGPDGTAAAVLLRAAALEDGTDVARGRRGELVH
CCEEEECCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCEEE
TAALARGPGNLCAAMGITMADNGIDLFDPDSPVTLRLHEPLTAVCGPRVGVSQAADRPWR
EHHHHCCCCCEEHHHCEEEECCCCCCCCCCCCEEEEECCCHHHHCCCCCCCHHHCCCCEE
LWLPGRPEVSAYRRSPRAPAPGTSD
EEECCCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA