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The map label for this gene is nadA

Identifier: 41407387

GI number: 41407387

Start: 1378000

End: 1379049

Strand: Direct

Name: nadA

Synonym: MAP1289

Alternate gene names: 41407387

Gene position: 1378000-1379049 (Clockwise)

Preceding gene: 41407385

Following gene: 41407388

Centisome position: 28.53

GC content: 68.48

Gene sequence:

>1050_bases
ATGACGGTGCTCAATCGCATGGACACGCTCGCTGAAGACATGGTTGCCGACATCACCGACTCGCCCACCGGTTACACCGG
TGTGGACGGCGATGCGCAGTGGGCCGCCGAGGTTCGCCGCCTGGCGAAGTTGCGCGGCGCCACCATCCTGGCGCACAACT
ACCAGCTGCCCGAGATCCAAGACGTGGCCGACCACGTGGGCGACTCGCTGGCGCTGTCGCGGATCGCCGCCGAGGCACCC
GAGGACACCATCGTGTTCTGCGGGGTGCACTTCATGGCCGAGACCGCCAAGATCCTCAGCCCCGACAAGACGGTGCTGAT
CCCCGACCAGCGCGCCGGCTGCTCGCTGGCCGACTCCATCACGCCCGAGGACCTGCGCGCCTGGAAGGACGAACACCCCG
GCGCGGTCGTCGTCTCCTACTTCAACACCACCGCGGCGGTCAAGGCGCTCACCGACATCTGCTGCACCTCGTCCAATGCG
GTCGACGTGGTGGCGTCCATCGACCCCGACCGCGAGGTGCTGTTCTGCCCCGACCAGTTCCTGGGCGCGCACGTGCGCCG
GATGACGGGCCGGGAAAACCTGCACGTGTGGGCCGGCGAATGCCACGTGCACGCCGGCATCAACGGCGACGAACTGGGTG
AGCGGGCGCGCGCCAACCCCGATGCCGAGCTATTCGTCCATCCCGAATGCGGTTGTGCCACTTCGGCTTTGTACCTTGCG
GGGGAGGGCGCCTTCCCCGCGGAACGGGTCAAGATCCTGTCCACCGGCGGCATGCTGGACGCCGCGAACACCACCAGCGC
GCGCAAGGTGCTGGTGGCCACCGAGGTCGGCATGCTCTACCAATTGCGCCGGGCCGCACCGCAAGTCGATTTCCAGGCCG
TCAACGACCGCGCCTCCTGCCGGTACATGAAGATGATCACCCCGGCGGCTCTGCTGCGCTGCCTGGTCGAGGGCGCCGAC
GAGGTGCACGTCGATCCCGGCATCGCGGCTGCCGGCCGGCGCAGCGTGCAGCGCATGATCGAGATCGGCCAGCCGGGCGG
TGGCGAATGA

Upstream 100 bases:

>100_bases
GCGAACCTGGAACACGACCGCGAGCACTTCGTGCGCGGTGCTACCATGGGCCATGTTTTCGATTATAAGTCGAAAACCTC
CTGGCCGGAAAGGAGCCGCC

Downstream 100 bases:

>100_bases
TCGCCCGTCCCCAGTGGACACACAGCGCCGACGTCGTCGTGATCGGCACCGGCGTCGCCGGATTGGCCGCCGCGCTGGCC
GCCCACCGCGCCGGCCGCAG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTVLNRMDTLAEDMVADITDSPTGYTGVDGDAQWAAEVRRLAKLRGATILAHNYQLPEIQDVADHVGDSLALSRIAAEAP
EDTIVFCGVHFMAETAKILSPDKTVLIPDQRAGCSLADSITPEDLRAWKDEHPGAVVVSYFNTTAAVKALTDICCTSSNA
VDVVASIDPDREVLFCPDQFLGAHVRRMTGRENLHVWAGECHVHAGINGDELGERARANPDAELFVHPECGCATSALYLA
GEGAFPAERVKILSTGGMLDAANTTSARKVLVATEVGMLYQLRRAAPQVDFQAVNDRASCRYMKMITPAALLRCLVEGAD
EVHVDPGIAAAGRRSVQRMIEIGQPGGGE

Sequences:

>Translated_349_residues
MTVLNRMDTLAEDMVADITDSPTGYTGVDGDAQWAAEVRRLAKLRGATILAHNYQLPEIQDVADHVGDSLALSRIAAEAP
EDTIVFCGVHFMAETAKILSPDKTVLIPDQRAGCSLADSITPEDLRAWKDEHPGAVVVSYFNTTAAVKALTDICCTSSNA
VDVVASIDPDREVLFCPDQFLGAHVRRMTGRENLHVWAGECHVHAGINGDELGERARANPDAELFVHPECGCATSALYLA
GEGAFPAERVKILSTGGMLDAANTTSARKVLVATEVGMLYQLRRAAPQVDFQAVNDRASCRYMKMITPAALLRCLVEGAD
EVHVDPGIAAAGRRSVQRMIEIGQPGGGE
>Mature_348_residues
TVLNRMDTLAEDMVADITDSPTGYTGVDGDAQWAAEVRRLAKLRGATILAHNYQLPEIQDVADHVGDSLALSRIAAEAPE
DTIVFCGVHFMAETAKILSPDKTVLIPDQRAGCSLADSITPEDLRAWKDEHPGAVVVSYFNTTAAVKALTDICCTSSNAV
DVVASIDPDREVLFCPDQFLGAHVRRMTGRENLHVWAGECHVHAGINGDELGERARANPDAELFVHPECGCATSALYLAG
EGAFPAERVKILSTGGMLDAANTTSARKVLVATEVGMLYQLRRAAPQVDFQAVNDRASCRYMKMITPAALLRCLVEGADE
VHVDPGIAAAGRRSVQRMIEIGQPGGGE

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=333, Percent_Identity=34.8348348348348, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37381; Mature: 37250

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLNRMDTLAEDMVADITDSPTGYTGVDGDAQWAAEVRRLAKLRGATILAHNYQLPEIQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHH
DVADHVGDSLALSRIAAEAPEDTIVFCGVHFMAETAKILSPDKTVLIPDQRAGCSLADSI
HHHHHCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCCCEEEECCCCCCCCHHCCC
TPEDLRAWKDEHPGAVVVSYFNTTAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQF
CHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCHHH
LGAHVRRMTGRENLHVWAGECHVHAGINGDELGERARANPDAELFVHPECGCATSALYLA
HHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEE
GEGAFPAERVKILSTGGMLDAANTTSARKVLVATEVGMLYQLRRAAPQVDFQAVNDRASC
CCCCCCHHHEEEEECCCCEECCCCCCHHEEEEEHHHHHHHHHHHHCCCCCCEECCCCHHH
RYMKMITPAALLRCLVEGADEVHVDPGIAAAGRRSVQRMIEIGQPGGGE
HHHHHHCHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TVLNRMDTLAEDMVADITDSPTGYTGVDGDAQWAAEVRRLAKLRGATILAHNYQLPEIQ
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHH
DVADHVGDSLALSRIAAEAPEDTIVFCGVHFMAETAKILSPDKTVLIPDQRAGCSLADSI
HHHHHCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCCCEEEECCCCCCCCHHCCC
TPEDLRAWKDEHPGAVVVSYFNTTAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQF
CHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCHHH
LGAHVRRMTGRENLHVWAGECHVHAGINGDELGERARANPDAELFVHPECGCATSALYLA
HHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEE
GEGAFPAERVKILSTGGMLDAANTTSARKVLVATEVGMLYQLRRAAPQVDFQAVNDRASC
CCCCCCHHHEEEEECCCCEECCCCCCHHEEEEEHHHHHHHHHHHHCCCCCCEECCCCHHH
RYMKMITPAALLRCLVEGADEVHVDPGIAAAGRRSVQRMIEIGQPGGGE
HHHHHHCHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA