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The map label for this gene is bioD

Identifier: 41407374

GI number: 41407374

Start: 1363319

End: 1364026

Strand: Direct

Name: bioD

Synonym: MAP1276

Alternate gene names: 41407374

Gene position: 1363319-1364026 (Clockwise)

Preceding gene: 41407373

Following gene: 41407375

Centisome position: 28.23

GC content: 75.85

Gene sequence:

>708_bases
ATGTGCTCGCCGGGCTCGGCTGAGGCCGTGACGGTTCTGGTCGTCACCGGCACCGACACCGGGGTCGGAAAGACGGTCGC
CACGGCGGCGCTGGCGTGTCATGCCCGTCAGGCCGGCATCGACGTGGCGGTGTGCAAACCGGTGCAGACCGGCACCGACG
ACGGCGACGACGACCTCGCCGAGGTGGCCCGGCTGTCCGGGGTGACCGAGCTGGCCGGGCTGGCCCGCTACCCGCGGCCG
CTGGCGCCGGTGGCCGCCGCCGCCGCGGCGGGGATGGCCTTGCCCAGCCGCGAGCAGCTGCTGGGGTTCATCGGCGAGCT
GGACCGGCCGGGGCGGCTGACGCTGGTCGAGGGCGCCGGGGGACTGCTGGTCGAGCTCGGCGAAAACGGTGTCACCGCAC
GCGATCTCGCCGTCGCGCTGGGCGCGGCGGTGCTGGTCGTGGTCCGGCCGGCGCTGGGCACCCTCAACCACACCGCGCTG
ACCCTGGAAGCGCTTGCCGCGCAGGGCCTTTCGTGTGCCGGGCTGGTGATCGGCGCCTGGCCCGAACATCCCGGCCCGGT
CGAGACGTCGAATCGGCCCGCGCTCGAAGCGCTTGCCCCGGTGCGCGCCGTGCTGCCCGCGGGGGCGGCGGCGCTGGCCG
CCGCCGAGTTCGAGGCCGTGAGCGCCGGCGCATTCGACCGCGACTGGGTCACCGCGCTGGCCGGCTGA

Upstream 100 bases:

>100_bases
CGTCCCCCGACGGTGCCCGCCGGGACGTCGCGGCTACGGCTGACCGCCCGCGCGTCGCTGGACGACGCCGAACTGGAGGT
CGCGCGCCGGGTGCTCACCG

Downstream 100 bases:

>100_bases
TGGTCCACTCGATCGAGCTGGTCTTCGACCCGGACACCGAGGCGGCCATCCGGCAGACCTGGAAAGCGTTGGCGGCGGCC
GGAATTCCCAGCCAGGCGCC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MCSPGSAEAVTVLVVTGTDTGVGKTVATAALACHARQAGIDVAVCKPVQTGTDDGDDDLAEVARLSGVTELAGLARYPRP
LAPVAAAAAAGMALPSREQLLGFIGELDRPGRLTLVEGAGGLLVELGENGVTARDLAVALGAAVLVVVRPALGTLNHTAL
TLEALAAQGLSCAGLVIGAWPEHPGPVETSNRPALEALAPVRAVLPAGAAALAAAEFEAVSAGAFDRDWVTALAG

Sequences:

>Translated_235_residues
MCSPGSAEAVTVLVVTGTDTGVGKTVATAALACHARQAGIDVAVCKPVQTGTDDGDDDLAEVARLSGVTELAGLARYPRP
LAPVAAAAAAGMALPSREQLLGFIGELDRPGRLTLVEGAGGLLVELGENGVTARDLAVALGAAVLVVVRPALGTLNHTAL
TLEALAAQGLSCAGLVIGAWPEHPGPVETSNRPALEALAPVRAVLPAGAAALAAAEFEAVSAGAFDRDWVTALAG
>Mature_235_residues
MCSPGSAEAVTVLVVTGTDTGVGKTVATAALACHARQAGIDVAVCKPVQTGTDDGDDDLAEVARLSGVTELAGLARYPRP
LAPVAAAAAAGMALPSREQLLGFIGELDRPGRLTLVEGAGGLLVELGENGVTARDLAVALGAAVLVVVRPALGTLNHTAL
TLEALAAQGLSCAGLVIGAWPEHPGPVETSNRPALEALAPVRAVLPAGAAALAAAEFEAVSAGAFDRDWVTALAG

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=172, Percent_Identity=34.3023255813954, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 23247; Mature: 23247

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSPGSAEAVTVLVVTGTDTGVGKTVATAALACHARQAGIDVAVCKPVQTGTDDGDDDLA
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHH
EVARLSGVTELAGLARYPRPLAPVAAAAAAGMALPSREQLLGFIGELDRPGRLTLVEGAG
HHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCC
GLLVELGENGVTARDLAVALGAAVLVVVRPALGTLNHTALTLEALAAQGLSCAGLVIGAW
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECC
PEHPGPVETSNRPALEALAPVRAVLPAGAAALAAAEFEAVSAGAFDRDWVTALAG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MCSPGSAEAVTVLVVTGTDTGVGKTVATAALACHARQAGIDVAVCKPVQTGTDDGDDDLA
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHH
EVARLSGVTELAGLARYPRPLAPVAAAAAAGMALPSREQLLGFIGELDRPGRLTLVEGAG
HHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCC
GLLVELGENGVTARDLAVALGAAVLVVVRPALGTLNHTALTLEALAAQGLSCAGLVIGAW
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECC
PEHPGPVETSNRPALEALAPVRAVLPAGAAALAAAEFEAVSAGAFDRDWVTALAG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA